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Page 1
NLRC5: back to innate immunity.
Guerra J, Guarda G. Guerra J, et al. Among authors: guarda g. Trends Immunol. 2024 Aug;45(8):571-573. doi: 10.1016/j.it.2024.07.002. Epub 2024 Jul 31. Trends Immunol. 2024. PMID: 39089973 Free article.
A Ménage à trois: NLRC5, immunity, and metabolism.
Brunschwiler F, Nakka S, Guerra J, Guarda G. Brunschwiler F, et al. Among authors: guarda g. Front Immunol. 2024 Jul 5;15:1426620. doi: 10.3389/fimmu.2024.1426620. eCollection 2024. Front Immunol. 2024. PMID: 39035010 Free PMC article. Review.
A first-in-class Wiskott-Aldrich syndrome protein activator with antitumor activity in hematologic cancers.
Spriano F, Sartori G, Sgrignani J, Barnabei L, Arribas AJ, Guala M, Del Amor AMC, Tomasso MR, Tarantelli C, Cascione L, Golino G, Riveiro ME, Bortolozzi R, Lupia A, Paduano F, Huguet S, Rezai K, Rinaldi A, Margheriti F, Ventura P, Guarda G, Costa G, Rocca R, Furlan A, Verdonk LM, Innocenti P, Martin NI, Viola G, Driessen C, Zucca E, Stathis A, Gahtory D, Van den Nieuwboer M, Bornhauser B, Alcaro S, Trapasso F, Cristobal S, Padrick SB, Pazzi N, Cavalli F, Cavalli A, Gaudio E, Bertoni F. Spriano F, et al. Among authors: guarda g. Haematologica. 2024 Nov 1;109(11):3602-3614. doi: 10.3324/haematol.2022.282672. Haematologica. 2024. PMID: 38899342 Free PMC article.
Patient-derived organoid biobank identifies epigenetic dysregulation of intestinal epithelial MHC-I as a novel mechanism in severe Crohn's Disease.
Dennison TW, Edgar RD, Payne F, Nayak KM, Ross ADB, Cenier A, Glemas C, Giachero F, Foster AR, Harris R, Kraiczy J, Salvestrini C, Stavrou G, Torrente F, Brook K, Trayers C, Elmentaite R, Youssef G, Tél B, Winton DJ, Skoufou-Papoutsaki N, Adler S, Bufler P, Azabdaftari A, Jenke A, G N, Thomas N, Miele E, Al-Mohammad A, Guarda G, Kugathasan S, Venkateswaran S, Clatworthy MR, Castro-Dopico T, Suchanek O, Strisciuglio C, Gasparetto M, Lee S, Xu X, Bello E, Han N, Zerbino DR, Teichmann SA, Nys J, Heuschkel R, Perrone F, Zilbauer M. Dennison TW, et al. Among authors: guarda g. Gut. 2024 Aug 8;73(9):1464-1477. doi: 10.1136/gutjnl-2024-332043. Gut. 2024. PMID: 38857990 Free PMC article.
The bacterial lysate OM-85 engages Toll-like receptors 2 and 4 triggering an immunomodulatory gene signature in human myeloid cells.
Khameneh HJ, Bolis M, Ventura PMO, Cassanmagnago GA, Fischer BA, Zenobi A, Guerra J, Buzzago I, Bernasconi M, Zaman GJR, Rinaldi A, Moro SG, Sallusto F, Baulier E, Pasquali C, Guarda G. Khameneh HJ, et al. Among authors: guarda g. Mucosal Immunol. 2024 Jun;17(3):346-358. doi: 10.1016/j.mucimm.2024.02.010. Epub 2024 Mar 4. Mucosal Immunol. 2024. PMID: 38447907 Free article.
Retinoic acid receptor activation reprograms senescence response and enhances anti-tumor activity of natural killer cells.
Colucci M, Zumerle S, Bressan S, Gianfanti F, Troiani M, Valdata A, D'Ambrosio M, Pasquini E, Varesi A, Cogo F, Mosole S, Dongilli C, Desbats MA, Contu L, Revankdar A, Chen J, Kalathur M, Perciato ML, Basilotta R, Endre L, Schauer S, Othman A, Guccini I, Saponaro M, Maraccani L, Bancaro N, Lai P, Liu L, Pernigoni N, Mele F, Merler S, Trotman LC, Guarda G, Calì B, Montopoli M, Alimonti A. Colucci M, et al. Among authors: guarda g. Cancer Cell. 2024 Apr 8;42(4):646-661.e9. doi: 10.1016/j.ccell.2024.02.004. Epub 2024 Feb 29. Cancer Cell. 2024. PMID: 38428412 Free PMC article.
Myc controls NK cell development, IL-15-driven expansion, and translational machinery.
Khameneh HJ, Fonta N, Zenobi A, Niogret C, Ventura P, Guerra C, Kwee I, Rinaldi A, Pecoraro M, Geiger R, Cavalli A, Bertoni F, Vivier E, Trumpp A, Guarda G. Khameneh HJ, et al. Among authors: guarda g. Life Sci Alliance. 2023 Apr 27;6(7):e202302069. doi: 10.26508/lsa.202302069. Print 2023 Jul. Life Sci Alliance. 2023. PMID: 37105715 Free PMC article.
SHP-1 localization to the activating immune synapse promotes NK cell tolerance in MHC class I deficiency.
Schmied L, Luu TT, Søndergaard JN, Hald SH, Meinke S, Mohammad DK, Singh SB, Mayer C, Perinetti Casoni G, Chrobok M, Schlums H, Rota G, Truong HM, Westerberg LS, Guarda G, Alici E, Wagner AK, Kadri N, Bryceson YT, Saeed MB, Höglund P. Schmied L, et al. Among authors: guarda g. Sci Signal. 2023 Apr 11;16(780):eabq0752. doi: 10.1126/scisignal.abq0752. Epub 2023 Apr 11. Sci Signal. 2023. PMID: 37040441
FOXC2 controls adult lymphatic endothelial specialization, function, and gut lymphatic barrier preventing multiorgan failure.
González-Loyola A, Bovay E, Kim J, Lozano TW, Sabine A, Renevey F, Arroz-Madeira S, Rapin A, Wypych TP, Rota G, Durot S, Velin D, Marsland B, Guarda G, Delorenzi M, Zamboni N, Luther SA, Petrova TV. González-Loyola A, et al. Among authors: guarda g. Sci Adv. 2021 Jul 16;7(29):eabf4335. doi: 10.1126/sciadv.abf4335. Print 2021 Jul. Sci Adv. 2021. PMID: 34272244 Free PMC article.
51 results