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Page 1
Patient-derived organoid biobank identifies epigenetic dysregulation of intestinal epithelial MHC-I as a novel mechanism in severe Crohn's Disease.
Dennison TW, Edgar RD, Payne F, Nayak KM, Ross ADB, Cenier A, Glemas C, Giachero F, Foster AR, Harris R, Kraiczy J, Salvestrini C, Stavrou G, Torrente F, Brook K, Trayers C, Elmentaite R, Youssef G, Tél B, Winton DJ, Skoufou-Papoutsaki N, Adler S, Bufler P, Azabdaftari A, Jenke A, G N, Thomas N, Miele E, Al-Mohammad A, Guarda G, Kugathasan S, Venkateswaran S, Clatworthy MR, Castro-Dopico T, Suchanek O, Strisciuglio C, Gasparetto M, Lee S, Xu X, Bello E, Han N, Zerbino DR, Teichmann SA, Nys J, Heuschkel R, Perrone F, Zilbauer M. Dennison TW, et al. Among authors: edgar rd. Gut. 2024 Aug 8;73(9):1464-1477. doi: 10.1136/gutjnl-2024-332043. Gut. 2024. PMID: 38857990 Free PMC article.
Transcription and DNA Methylation Patterns of Blood-Derived CD8+ T Cells Are Associated With Age and Inflammatory Bowel Disease But Do Not Predict Prognosis.
Gasparetto M, Payne F, Nayak K, Kraiczy J, Glemas C, Philip-McKenzie Y, Ross A, Edgar RD, Zerbino DR, Salvestrini C, Torrente F, Ventham NT, Kalla R, Satsangi J, Sarkies P, Heuschkel R, Zilbauer M. Gasparetto M, et al. Among authors: edgar rd. Gastroenterology. 2021 Jan;160(1):232-244.e7. doi: 10.1053/j.gastro.2020.08.017. Epub 2020 Aug 16. Gastroenterology. 2021. PMID: 32814113 Free PMC article.
Culture-Associated DNA Methylation Changes Impact on Cellular Function of Human Intestinal Organoids.
Edgar RD, Perrone F, Foster AR, Payne F, Lewis S, Nayak KM, Kraiczy J, Cenier A, Torrente F, Salvestrini C, Heuschkel R, Hensel KO, Harris R, Jones DL, Zerbino DR, Zilbauer M. Edgar RD, et al. Cell Mol Gastroenterol Hepatol. 2022;14(6):1295-1310. doi: 10.1016/j.jcmgh.2022.08.008. Epub 2022 Aug 28. Cell Mol Gastroenterol Hepatol. 2022. PMID: 36038072 Free PMC article.
The PedBE clock accurately estimates DNA methylation age in pediatric buccal cells.
McEwen LM, O'Donnell KJ, McGill MG, Edgar RD, Jones MJ, MacIsaac JL, Lin DTS, Ramadori K, Morin A, Gladish N, Garg E, Unternaehrer E, Pokhvisneva I, Karnani N, Kee MZL, Klengel T, Adler NE, Barr RG, Letourneau N, Giesbrecht GF, Reynolds JN, Czamara D, Armstrong JM, Essex MJ, de Weerth C, Beijers R, Tollenaar MS, Bradley B, Jovanovic T, Ressler KJ, Steiner M, Entringer S, Wadhwa PD, Buss C, Bush NR, Binder EB, Boyce WT, Meaney MJ, Horvath S, Kobor MS. McEwen LM, et al. Among authors: edgar rd. Proc Natl Acad Sci U S A. 2020 Sep 22;117(38):23329-23335. doi: 10.1073/pnas.1820843116. Epub 2019 Oct 14. Proc Natl Acad Sci U S A. 2020. PMID: 31611402 Free PMC article.
DNA methylation signature of human fetal alcohol spectrum disorder.
Portales-Casamar E, Lussier AA, Jones MJ, MacIsaac JL, Edgar RD, Mah SM, Barhdadi A, Provost S, Lemieux-Perreault LP, Cynader MS, Chudley AE, Dubé MP, Reynolds JN, Pavlidis P, Kobor MS. Portales-Casamar E, et al. Among authors: edgar rd. Epigenetics Chromatin. 2016 Jun 29;9:25. doi: 10.1186/s13072-016-0074-4. eCollection 2016. Epigenetics Chromatin. 2016. PMID: 27358653 Free PMC article.
Systems Biology Methods Applied to Blood and Tissue for a Comprehensive Analysis of Immune Response to Hepatitis B Vaccine in Adults.
Ben-Othman R, Cai B, Liu AC, Varankovich N, He D, Blimkie TM, Lee AH, Gill EE, Novotny M, Aevermann B, Drissler S, Shannon CP, McCann S, Marty K, Bjornson G, Edgar RD, Lin DTS, Gladish N, Maclsaac J, Amenyogbe N, Chan Q, Llibre A, Collin J, Landais E, Le K, Reiss SM, Koff WC, Havenar-Daughton C, Heran M, Sangha B, Walt D, Krajden M, Crotty S, Sok D, Briney B, Burton DR, Duffy D, Foster LJ, Mohn WW, Kobor MS, Tebbutt SJ, Brinkman RR, Scheuermann RH, Hancock REW, Kollmann TR, Sadarangani M. Ben-Othman R, et al. Among authors: edgar rd. Front Immunol. 2020 Nov 4;11:580373. doi: 10.3389/fimmu.2020.580373. eCollection 2020. Front Immunol. 2020. PMID: 33250895 Free PMC article. Clinical Trial.
Brain DNA Methylation Patterns in CLDN5 Associated With Cognitive Decline.
Hüls A, Robins C, Conneely KN, Edgar R, De Jager PL, Bennett DA, Wingo AP, Epstein MP, Wingo TS. Hüls A, et al. Biol Psychiatry. 2022 Feb 15;91(4):389-398. doi: 10.1016/j.biopsych.2021.01.015. Epub 2021 Feb 3. Biol Psychiatry. 2022. PMID: 33838873 Free PMC article.
Impacts of the COVID-19 pandemic on hepatitis C elimination in Canada: Where do we go from here?
Atif J, Udhesister STP, Abdelnabi MN, D'Souza S, Hung JH, Edgar RD, Gobran ST, Gomez-Escobar E, Greenwald ZR, Gallardo-Flores CE, Fontaine G, Jeong D, Lanièce-Delaunay C, Lawton D, Makuza JD, Masterman C, Marathe G, Mortazhejri S, Li J, Palmer M, Passos-Castilho AM, Sag M, Shengir M, Wallace HL, Mendlowitz AB; 2022–2023 trainees of the Canadian Network on Hepatitis C. Atif J, et al. Among authors: edgar rd. Can Liver J. 2022 Nov 7;5(4):441-444. doi: 10.3138/canlivj-2022-0035. eCollection 2022 Nov. Can Liver J. 2022. PMID: 38144406 Free PMC article. No abstract available.
18 results