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459 results

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Page 1
Exploring Integrin α5β1 as a Potential Therapeutic Target for Pulmonary Arterial Hypertension: Insights from Comprehensive Multicenter Preclinical Studies.
Lemay SE, Montesinos MS, Grobs Y, Yokokawa T, Shimauchi T, Romanet C, Sauvaget M, Breuils-Bonnet S, Bourgeois A, Théberge C, Pelletier A, El Kabbout R, Martineau S, Yamamoto K, Ray AS, Lippa B, Goodwin B, Lin FY, Wang H, Dowling JE, Lu M, Qiao Q, McTeague TA, Moy TI, Potus F, Provencher S, Boucherat O, Bonnet S. Lemay SE, et al. Among authors: bourgeois a. bioRxiv [Preprint]. 2024 Jun 1:2024.05.27.596052. doi: 10.1101/2024.05.27.596052. bioRxiv. 2024. PMID: 38854025 Free PMC article. Preprint.
Preclinical Investigation of Trifluoperazine as a Novel Therapeutic Agent for the Treatment of Pulmonary Arterial Hypertension.
Grobs Y, Awada C, Lemay SE, Romanet C, Bourgeois A, Toro V, Nadeau V, Shimauchi K, Orcholski M, Breuils-Bonnet S, Tremblay E, Provencher S, Paulin R, Boucherat O, Bonnet S. Grobs Y, et al. Among authors: bourgeois a. Int J Mol Sci. 2021 Mar 13;22(6):2919. doi: 10.3390/ijms22062919. Int J Mol Sci. 2021. PMID: 33805714 Free PMC article.
Hypusine Signaling Promotes Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension.
Lemay SE, Grobs Y, Romanet C, Martineau S, Salem M, Shimauchi T, Breuils-Bonnet S, Bourgeois A, Théberge C, Pelletier A, Potus F, Provencher S, Bonnet S, Boucherat O. Lemay SE, et al. Among authors: bourgeois a. Am J Respir Crit Care Med. 2024 Jun 1;209(11):1376-1391. doi: 10.1164/rccm.202305-0909OC. Am J Respir Crit Care Med. 2024. PMID: 38261723
Potential for inhibition of checkpoint kinases 1/2 in pulmonary fibrosis and secondary pulmonary hypertension.
Wu WH, Bonnet S, Shimauchi T, Toro V, Grobs Y, Romanet C, Bourgeois A, Vitry G, Omura J, Tremblay E, Nadeau V, Orcholski M, Breuils-Bonnet S, Martineau S, Ferraro P, Potus F, Paulin R, Provencher S, Boucherat O. Wu WH, et al. Among authors: bourgeois a. Thorax. 2022 Mar;77(3):247-258. doi: 10.1136/thoraxjnl-2021-217377. Epub 2021 Jul 5. Thorax. 2022. PMID: 34226205
HDAC6: A Novel Histone Deacetylase Implicated in Pulmonary Arterial Hypertension.
Boucherat O, Chabot S, Paulin R, Trinh I, Bourgeois A, Potus F, Lampron MC, Lambert C, Breuils-Bonnet S, Nadeau V, Paradis R, Goncharova EA, Provencher S, Bonnet S. Boucherat O, et al. Among authors: bourgeois a. Sci Rep. 2017 Jul 3;7(1):4546. doi: 10.1038/s41598-017-04874-4. Sci Rep. 2017. PMID: 28674407 Free PMC article.
Multicenter Preclinical Validation of BET Inhibition for the Treatment of Pulmonary Arterial Hypertension.
Van der Feen DE, Kurakula K, Tremblay E, Boucherat O, Bossers GPL, Szulcek R, Bourgeois A, Lampron MC, Habbout K, Martineau S, Paulin R, Kulikowski E, Jahagirdar R, Schalij I, Bogaard HJ, Bartelds B, Provencher S, Berger RMF, Bonnet S, Goumans MJ. Van der Feen DE, et al. Among authors: bourgeois a. Am J Respir Crit Care Med. 2019 Oct 1;200(7):910-920. doi: 10.1164/rccm.201812-2275OC. Am J Respir Crit Care Med. 2019. PMID: 31042405
Inhibition of CHK 1 (Checkpoint Kinase 1) Elicits Therapeutic Effects in Pulmonary Arterial Hypertension.
Bourgeois A, Bonnet S, Breuils-Bonnet S, Habbout K, Paradis R, Tremblay E, Lampron MC, Orcholski ME, Potus F, Bertero T, Peterlini T, Chan SY, Norris KA, Paulin R, Provencher S, Boucherat O. Bourgeois A, et al. Arterioscler Thromb Vasc Biol. 2019 Aug;39(8):1667-1681. doi: 10.1161/ATVBAHA.119.312537. Epub 2019 May 16. Arterioscler Thromb Vasc Biol. 2019. PMID: 31092016 Free PMC article.
Oxidized DNA Precursors Cleanup by NUDT1 Contributes to Vascular Remodeling in Pulmonary Arterial Hypertension.
Vitry G, Paulin R, Grobs Y, Lampron MC, Shimauchi T, Lemay SE, Tremblay E, Habbout K, Awada C, Bourgeois A, Nadeau V, Paradis R, Breuils-Bonnet S, Roux-Dalvai F, Orcholski M, Potus F, Provencher S, Boucherat O, Bonnet S. Vitry G, et al. Among authors: bourgeois a. Am J Respir Crit Care Med. 2021 Mar 1;203(5):614-627. doi: 10.1164/rccm.202003-0627OC. Am J Respir Crit Care Med. 2021. PMID: 33021405
459 results