Heydt C - Search Results

1

Multinational proficiency tests for EGFR exon 20 insertions reveal that the assay design matters.

Ihle MA, Heydt C, Schultheis AM, Stöhr R, Haller F, Herold S, Aust D, Dietmaier W, Evert M, Eszlinger M, Haak A, Laßmann S, Vorholt D, Breitenbücher F, Werner M, Streubel A, Mairinger T, Grassow-Narlik M, Merkelbach-Bruse S. Ihle MA, et al. Among authors: heydt c. Sci Rep. 2024 Jun 6;14(1):13069. doi: 10.1038/s41598-024-63821-2. Sci Rep. 2024. PMID: 38844820 Free PMC article.

2

The impact of sequencing on diagnosis and treatment of malignant melanoma.

Castiglione R, Ihle MA, Heydt C, Schultheis AM, Merkelbach-Bruse S, Mauch C, Büttner R. Castiglione R, et al. Among authors: heydt c. Expert Rev Mol Diagn. 2016;16(4):423-33. doi: 10.1586/14737159.2016.1147958. Epub 2016 Feb 19. Expert Rev Mol Diagn. 2016. PMID: 26822148 Review.

3

Mutational spectrum of acquired resistance to reversible versus irreversible EGFR tyrosine kinase inhibitors.

Wagener-Ryczek S, Heydt C, Süptitz J, Michels S, Falk M, Alidousty C, Fassunke J, Ihle MA, Tiemann M, Heukamp L, Wolf J, Büttner R, Merkelbach-Bruse S. Wagener-Ryczek S, et al. Among authors: heydt c. BMC Cancer. 2020 May 12;20(1):408. doi: 10.1186/s12885-020-06920-3. BMC Cancer. 2020. PMID: 32397977 Free PMC article.

4

Analysis of tumor mutational burden: correlation of five large gene panels with whole exome sequencing.

Heydt C, Rehker J, Pappesch R, Buhl T, Ball M, Siebolts U, Haak A, Lohneis P, Büttner R, Hillmer AM, Merkelbach-Bruse S. Heydt C, et al. Sci Rep. 2020 Jul 9;10(1):11387. doi: 10.1038/s41598-020-68394-4. Sci Rep. 2020. PMID: 32647293 Free PMC article.

5

Overview of Molecular Detection Technologies for MET in Lung Cancer.

Heydt C, Ihle MA, Merkelbach-Bruse S. Heydt C, et al. Cancers (Basel). 2023 May 26;15(11):2932. doi: 10.3390/cancers15112932. Cancers (Basel). 2023. PMID: 37296895 Free PMC article. Review.

6

Comparison of pre-analytical FFPE sample preparation methods and their impact on massively parallel sequencing in routine diagnostics.

Heydt C, Fassunke J, Künstlinger H, Ihle MA, König K, Heukamp LC, Schildhaus HU, Odenthal M, Büttner R, Merkelbach-Bruse S. Heydt C, et al. PLoS One. 2014 Aug 8;9(8):e104566. doi: 10.1371/journal.pone.0104566. eCollection 2014. PLoS One. 2014. PMID: 25105902 Free PMC article.

7

Massively parallel sequencing fails to detect minor resistant subclones in tissue samples prior to tyrosine kinase inhibitor therapy.

Heydt C, Kumm N, Fassunke J, Künstlinger H, Ihle MA, Scheel A, Schildhaus HU, Haller F, Büttner R, Odenthal M, Wardelmann E, Merkelbach-Bruse S. Heydt C, et al. BMC Cancer. 2015 Apr 15;15:291. doi: 10.1186/s12885-015-1311-0. BMC Cancer. 2015. PMID: 25886408 Free PMC article.

8

Comparison of in Situ and Extraction-Based Methods for the Detection of ROS1 Rearrangements in Solid Tumors.

Heydt C, Ruesseler V, Pappesch R, Wagener S, Haak A, Siebolts U, Riedel R, Michels S, Wolf J, Schultheis AM, Rehker J, Buettner R, Merkelbach-Bruse S. Heydt C, et al. J Mol Diagn. 2019 Nov;21(6):971-984. doi: 10.1016/j.jmoldx.2019.06.006. Epub 2019 Aug 2. J Mol Diagn. 2019. PMID: 31382035 Free article.

9

Predictive molecular pathology of lung cancer in Germany with focus on gene fusion testing: Methods and quality assurance.

Siemanowski J, Heydt C, Merkelbach-Bruse S. Siemanowski J, et al. Among authors: heydt c. Cancer Cytopathol. 2020 Sep;128(9):611-621. doi: 10.1002/cncy.22293. Cancer Cytopathol. 2020. PMID: 32885916 Free article. Review.

10

Detection of gene fusions using targeted next-generation sequencing: a comparative evaluation.

Heydt C, Wölwer CB, Velazquez Camacho O, Wagener-Ryczek S, Pappesch R, Siemanowski J, Rehker J, Haller F, Agaimy A, Worm K, Herold T, Pfarr N, Weichert W, Kirchner T, Jung A, Kumbrink J, Goering W, Esposito I, Buettner R, Hillmer AM, Merkelbach-Bruse S. Heydt C, et al. BMC Med Genomics. 2021 Feb 27;14(1):62. doi: 10.1186/s12920-021-00909-y. BMC Med Genomics. 2021. PMID: 33639937 Free PMC article.

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