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The ribotoxic stress response drives UV-mediated cell death.
Sinha NK, McKenney C, Yeow ZY, Li JJ, Nam KH, Yaron-Barir TM, Johnson JL, Huntsman EM, Cantley LC, Ordureau A, Regot S, Green R. Sinha NK, et al. Among authors: nam kh. Cell. 2024 Jul 11;187(14):3652-3670.e40. doi: 10.1016/j.cell.2024.05.018. Epub 2024 Jun 5. Cell. 2024. PMID: 38843833 Free article.
NAK-associated protein 1/NAP1 activates TBK1 to ensure accurate mitosis and cytokinesis.
Paul S, Sarraf SA, Nam KH, Zavar L, DeFoor N, Biswas SR, Fritsch LE, Yaron TM, Johnson JL, Huntsman EM, Cantley LC, Ordureau A, Pickrell AM. Paul S, et al. Among authors: nam kh. J Cell Biol. 2024 Feb 5;223(2):e202303082. doi: 10.1083/jcb.202303082. Epub 2023 Dec 7. J Cell Biol. 2024. PMID: 38059900 Free PMC article.
Disruption of lysosomal proteolysis in astrocytes facilitates midbrain organoid proteostasis failure in an early-onset Parkinson's disease model.
Morrone Parfitt G, Coccia E, Goldman C, Whitney K, Reyes R, Sarrafha L, Nam KH, Sohail S, Jones DR, Crary JF, Ordureau A, Blanchard J, Ahfeldt T. Morrone Parfitt G, et al. Among authors: nam kh. Nat Commun. 2024 Jan 10;15(1):447. doi: 10.1038/s41467-024-44732-2. Nat Commun. 2024. PMID: 38200091 Free PMC article.
782 results