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A culture method with berbamine, a plant alkaloid, enhances CAR-T cell efficacy through modulating cellular metabolism.
Takayanagi SI, Chuganji S, Tanaka M, Wang B, Hasegawa S, Fukumoto K, Wasano N, Kakitani M, Ochiai N, Kawai Y, Ueda T, Ishikawa A, Kurimoto Y, Fukui A, Kamibayashi S, Imai E, Kunisato A, Nozawa H, Kaneko S. Takayanagi SI, et al. Among authors: chuganji s. Commun Biol. 2024 Jun 4;7(1):685. doi: 10.1038/s42003-024-06297-0. Commun Biol. 2024. PMID: 38834758 Free PMC article.
Mini-TCRs: Truncated T cell receptors to generate T cells from induced pluripotent stem cells.
Takayanagi SI, Wang B, Hasegawa S, Nishikawa S, Fukumoto K, Nakano K, Chuganji S, Kato Y, Kamibayashi S, Minagawa A, Kunisato A, Nozawa H, Kaneko S. Takayanagi SI, et al. Among authors: chuganji s. Mol Ther Methods Clin Dev. 2023 Sep 16;31:101109. doi: 10.1016/j.omtm.2023.101109. eCollection 2023 Dec 14. Mol Ther Methods Clin Dev. 2023. PMID: 37822720 Free PMC article.