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Alzheimer's disease protective allele of Clusterin modulates neuronal excitability through lipid-droplet-mediated neuron-glia communication.
Zhao X, Li Y, Zhang S, Sudwarts A, Zhang H, Kozlova A, Moulton MJ, Goodman LD, Pang ZP, Sanders AR, Bellen HJ, Thinakaran G, Duan J. Zhao X, et al. Among authors: sudwarts a. medRxiv [Preprint]. 2024 Aug 15:2024.08.14.24312009. doi: 10.1101/2024.08.14.24312009. medRxiv. 2024. PMID: 39185522 Free PMC article. Preprint.
Alzheimer's disease risk allele of PICALM causes detrimental lipid droplets in microglia.
Kozlova A, Zhang S, Sudwarts A, Zhang H, Smirnou S, Sun X, Stephenson K, Zhao X, Jamison B, Ponnusamy M, He X, Pang ZP, Sanders AR, Bellen HJ, Thinakaran G, Duan J. Kozlova A, et al. Among authors: sudwarts a. Res Sq [Preprint]. 2024 May 24:rs.3.rs-4407146. doi: 10.21203/rs.3.rs-4407146/v1. Res Sq. 2024. PMID: 38826437 Free PMC article. Preprint.
Neuronal BIN1 Regulates Presynaptic Neurotransmitter Release and Memory Consolidation.
De Rossi P, Nomura T, Andrew RJ, Masse NY, Sampathkumar V, Musial TF, Sudwarts A, Recupero AJ, Le Metayer T, Hansen MT, Shim HN, Krause SV, Freedman DJ, Bindokas VP, Kasthuri N, Nicholson DA, Contractor A, Thinakaran G. De Rossi P, et al. Among authors: sudwarts a. Cell Rep. 2020 Mar 10;30(10):3520-3535.e7. doi: 10.1016/j.celrep.2020.02.026. Cell Rep. 2020. PMID: 32160554 Free PMC article.