Holtzman DM - Search Results

1

Co-aggregation with Apolipoprotein E modulates the function of Amyloid-β in Alzheimer's disease.

Xia Z, Prescott EE, Urbanek A, Wareing HE, King MC, Olerinyova A, Dakin H, Leah T, Barnes KA, Matuszyk MM, Dimou E, Hidari E, Zhang YP, Lam JYL, Danial JSH, Strickland MR, Jiang H, Thornton P, Crowther DC, Ohtonen S, Gómez-Budia M, Bell SM, Ferraiuolo L, Mortiboys H, Higginbottom A, Wharton SB, Holtzman DM, Malm T, Ranasinghe RT, Klenerman D, De S. Xia Z, et al. Among authors: holtzman dm. Nat Commun. 2024 Jun 1;15(1):4695. doi: 10.1038/s41467-024-49028-z. Nat Commun. 2024. PMID: 38824138 Free PMC article.

2

High density lipoprotein decreases beta-amyloid toxicity in cortical cell culture.

Farhangrazi ZS, Ying H, Bu G, Dugan LL, Fagan AM, Choi DW, Holtzman DM. Farhangrazi ZS, et al. Among authors: holtzman dm. Neuroreport. 1997 Mar 24;8(5):1127-30. doi: 10.1097/00001756-199703240-00013. Neuroreport. 1997. PMID: 9175098

3

Expression of human apolipoprotein E reduces amyloid-beta deposition in a mouse model of Alzheimer's disease.

Holtzman DM, Bales KR, Wu S, Bhat P, Parsadanian M, Fagan AM, Chang LK, Sun Y, Paul SM. Holtzman DM, et al. J Clin Invest. 1999 Mar;103(6):R15-R21. doi: 10.1172/JCI6179. J Clin Invest. 1999. PMID: 10079115 Free PMC article.

4

Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease.

Holtzman DM, Bales KR, Tenkova T, Fagan AM, Parsadanian M, Sartorius LJ, Mackey B, Olney J, McKeel D, Wozniak D, Paul SM. Holtzman DM, et al. Proc Natl Acad Sci U S A. 2000 Mar 14;97(6):2892-7. doi: 10.1073/pnas.050004797. Proc Natl Acad Sci U S A. 2000. PMID: 10694577 Free PMC article.

5

Apolipoprotein E facilitates neuritic and cerebrovascular plaque formation in an Alzheimer's disease model.

Holtzman DM, Fagan AM, Mackey B, Tenkova T, Sartorius L, Paul SM, Bales K, Ashe KH, Irizarry MC, Hyman BT. Holtzman DM, et al. Ann Neurol. 2000 Jun;47(6):739-47. Ann Neurol. 2000. PMID: 10852539

6

Differences in the Abeta40/Abeta42 ratio associated with cerebrospinal fluid lipoproteins as a function of apolipoprotein E genotype.

Fagan AM, Younkin LH, Morris JC, Fryer JD, Cole TG, Younkin SG, Holtzman DM. Fagan AM, et al. Among authors: holtzman dm. Ann Neurol. 2000 Aug;48(2):201-10. Ann Neurol. 2000. PMID: 10939571

7

Expression of human apolipoprotein E downregulates amyloid precursor protein-induced ischemic susceptibility.

Koistinaho M, Kettunen MI, Holtzman DM, Kauppinen RA, Higgins LS, Koistinaho J. Koistinaho M, et al. Among authors: holtzman dm. Stroke. 2002 Jul;33(7):1905-10. doi: 10.1161/01.str.0000020124.61998.bc. Stroke. 2002. PMID: 12105373

8

Apolipoprotein E4 influences amyloid deposition but not cell loss after traumatic brain injury in a mouse model of Alzheimer's disease.

Hartman RE, Laurer H, Longhi L, Bales KR, Paul SM, McIntosh TK, Holtzman DM. Hartman RE, et al. Among authors: holtzman dm. J Neurosci. 2002 Dec 1;22(23):10083-7. doi: 10.1523/JNEUROSCI.22-23-10083.2002. J Neurosci. 2002. PMID: 12451108 Free PMC article.

9

Apolipoprotein E markedly facilitates age-dependent cerebral amyloid angiopathy and spontaneous hemorrhage in amyloid precursor protein transgenic mice.

Fryer JD, Taylor JW, DeMattos RB, Bales KR, Paul SM, Parsadanian M, Holtzman DM. Fryer JD, et al. Among authors: holtzman dm. J Neurosci. 2003 Aug 27;23(21):7889-96. doi: 10.1523/JNEUROSCI.23-21-07889.2003. J Neurosci. 2003. PMID: 12944519 Free PMC article.

10

Apolipoprotein E, amyloid, and Alzheimer disease.

Bales KR, Dodart JC, DeMattos RB, Holtzman DM, Paul SM. Bales KR, et al. Among authors: holtzman dm. Mol Interv. 2002 Oct;2(6):363-75, 339. doi: 10.1124/mi.2.6.363. Mol Interv. 2002. PMID: 14993413 Review.

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