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Page 1
Whole-genome sequencing uncovers two loci for coronary artery calcification and identifies ARSE as a regulator of vascular calcification.
de Vries PS, Conomos MP, Singh K, Nicholson CJ, Jain D, Hasbani NR, Jiang W, Lee S, Lino Cardenas CL, Lutz SM, Wong D, Guo X, Yao J, Young EP, Tcheandjieu C, Hilliard AT, Bis JC, Bielak LF, Brown MR, Musharoff S, Clarke SL, Terry JG, Palmer ND, Yanek LR, Xu H, Heard-Costa N, Wessel J, Selvaraj MS, Li RH, Sun X, Turner AW, Stilp AM, Khan A, Newman AB, Rasheed A, Freedman BI, Kral BG, McHugh CP, Hodonsky C, Saleheen D, Herrington DM, Jacobs DR Jr, Nickerson DA, Boerwinkle E, Wang FF, Heiss G, Jun G, Kinney GL, Sigurslid HH, Doddapaneni H, Hall IM, Bensenor IM, Broome J, Crapo JD, Wilson JG, Smith JA, Blangero J, Vargas JD, Mosquera JV, Smith JD, Viaud-Martinez KA, Ryan KA, Young KA, Taylor KD, Lange LA, Emery LS, Bittencourt MS, Budoff MJ, Montasser ME, Yu M, Mahaney MC, Mahamdeh MS, Fornage M, Franceschini N, Lotufo PA, Natarajan P, Wong Q, Mathias RA, Gibbs RA, Do R, Mehran R, Tracy RP, Kim RW, Nelson SC, Damrauer SM, Kardia SLR, Rich SS, Fuster V, Napolioni V, Zhao W, Tian W, Yin X, Min YI, Manning AK, Peloso G, Kelly TN, O'Donnell CJ, Morrison AC, Curran JE, Zapol WM, Bowden DW, Becker LC, Correa A, Mitchell BD, Psaty BM, Carr JJ, Pereira AC, Assimes TL, Stitziel NO, Hoka… See abstract for full author list ➔ de Vries PS, et al. Among authors: lino cardenas cl. Nat Cardiovasc Res. 2023 Dec;2(12):1159-1172. doi: 10.1038/s44161-023-00375-y. Epub 2023 Dec 4. Nat Cardiovasc Res. 2023. PMID: 38817323 Free PMC article.
Treatment of calcific arterial disease via enhancement of autophagy using GSK343.
Lino Cardenas CL, Jiang W, Kajuluri LP, Singh K, Ostrom K, Li R, Cherbonneau F, Boerboom S, Birchenough C, Roh K, Chou EL, Shahrooz Z, Nicholson C, Johnson AL, Lee S, Ichinose F, Bloch DB, Nigwekar S, Ellinor PT, Musolino P, Lindsay ME, Dou Z, Miller CL, Malhotra R. Lino Cardenas CL, et al. iScience. 2023 Oct 29;26(11):108360. doi: 10.1016/j.isci.2023.108360. eCollection 2023 Nov 17. iScience. 2023. PMID: 38033629 Free PMC article.
Integrative single-cell meta-analysis reveals disease-relevant vascular cell states and markers in human atherosclerosis.
Mosquera JV, Auguste G, Wong D, Turner AW, Hodonsky CJ, Alvarez-Yela AC, Song Y, Cheng Q, Lino Cardenas CL, Theofilatos K, Bos M, Kavousi M, Peyser PA, Mayr M, Kovacic JC, Björkegren JLM, Malhotra R, Stukenberg PT, Finn AV, van der Laan SW, Zang C, Sheffield NC, Miller CL. Mosquera JV, et al. Among authors: lino cardenas cl. Cell Rep. 2023 Nov 28;42(11):113380. doi: 10.1016/j.celrep.2023.113380. Epub 2023 Nov 10. Cell Rep. 2023. PMID: 37950869 Free article.
Multi-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification.
Kavousi M, Bos MM, Barnes HJ, Lino Cardenas CL, Wong D, Lu H, Hodonsky CJ, Landsmeer LPL, Turner AW, Kho M, Hasbani NR, de Vries PS, Bowden DW, Chopade S, Deelen J, Benavente ED, Guo X, Hofer E, Hwang SJ, Lutz SM, Lyytikäinen LP, Slenders L, Smith AV, Stanislawski MA, van Setten J, Wong Q, Yanek LR, Becker DM, Beekman M, Budoff MJ, Feitosa MF, Finan C, Hilliard AT, Kardia SLR, Kovacic JC, Kral BG, Langefeld CD, Launer LJ, Malik S, Hoesein FAAM, Mokry M, Schmidt R, Smith JA, Taylor KD, Terry JG, van der Grond J, van Meurs J, Vliegenthart R, Xu J, Young KA, Zilhão NR, Zweiker R, Assimes TL, Becker LC, Bos D, Carr JJ, Cupples LA, de Kleijn DPV, de Winther M, den Ruijter HM, Fornage M, Freedman BI, Gudnason V, Hingorani AD, Hokanson JE, Ikram MA, Išgum I, Jacobs DR Jr, Kähönen M, Lange LA, Lehtimäki T, Pasterkamp G, Raitakari OT, Schmidt H, Slagboom PE, Uitterlinden AG, Vernooij MW, Bis JC, Franceschini N, Psaty BM, Post WS, Rotter JI, Björkegren JLM, O'Donnell CJ, Bielak LF, Peyser PA, Malhotra R, van der Laan SW, Miller CL. Kavousi M, et al. Among authors: lino cardenas cl. Nat Genet. 2023 Oct;55(10):1651-1664. doi: 10.1038/s41588-023-01518-4. Epub 2023 Sep 28. Nat Genet. 2023. PMID: 37770635 Free PMC article.
FHL5 Controls Vascular Disease-Associated Gene Programs in Smooth Muscle Cells.
Wong D, Auguste G, Lino Cardenas CL, Turner AW, Chen Y, Song Y, Ma L, Perry RN, Aherrahrou R, Kuppusamy M, Yang C, Mosquera JV, Dube CJ, Khan MD, Palmore M, Kalra J, Kavousi M, Peyser PA, Matic L, Hedin U, Manichaikul A, Sonkusare SK, Civelek M, Kovacic JC, Björkegren JLM, Malhotra R, Miller CL. Wong D, et al. Among authors: lino cardenas cl. Circ Res. 2023 Apr 28;132(9):1144-1161. doi: 10.1161/CIRCRESAHA.122.321692. Epub 2023 Apr 5. Circ Res. 2023. PMID: 37017084 Free PMC article.
Co-occurring pathogenic variants in 6q27 associated with dementia spectrum disorders in a Peruvian family.
Alvarez KLF, Aguilar-Pineda JA, Ortiz-Manrique MM, Paredes-Calderon MF, Cardenas-Quispe BC, Vera-Lopez KJ, Goyzueta-Mamani LD, Chavez-Fumagalli MA, Davila-Del-Carpio G, Peralta-Mestas A, Musolino PL, Lino Cardenas CL. Alvarez KLF, et al. Among authors: lino cardenas cl. Front Mol Neurosci. 2023 Feb 16;16:1104585. doi: 10.3389/fnmol.2023.1104585. eCollection 2023. Front Mol Neurosci. 2023. PMID: 36873109 Free PMC article.
Aortic Cellular Diversity and Quantitative Genome-Wide Association Study Trait Prioritization Through Single-Nuclear RNA Sequencing of the Aneurysmal Human Aorta.
Chou EL, Chaffin M, Simonson B, Pirruccello JP, Akkad AD, Nekoui M, Lino Cardenas CL, Bedi KC Jr, Nash C, Juric D, Stone JR, Isselbacher EM, Margulies KB, Klattenhoff C, Ellinor PT, Lindsay ME. Chou EL, et al. Among authors: lino cardenas cl. Arterioscler Thromb Vasc Biol. 2022 Nov;42(11):1355-1374. doi: 10.1161/ATVBAHA.122.317953. Epub 2022 Sep 29. Arterioscler Thromb Vasc Biol. 2022. PMID: 36172868 Free PMC article.
In Silico Analysis of the Antagonist Effect of Enoxaparin on the ApoE4-Amyloid-Beta (Aβ) Complex at Different pH Conditions.
Aguilar-Pineda JA, Paco-Coralla SG, Febres-Molina C, Gamero-Begazo PL, Shrivastava P, Vera-López KJ, Davila-Del-Carpio G, López-C P, Gómez B, Lino Cardenas CL. Aguilar-Pineda JA, et al. Among authors: lino cardenas cl. Biomolecules. 2022 Mar 25;12(4):499. doi: 10.3390/biom12040499. Biomolecules. 2022. PMID: 35454088 Free PMC article.
44 results