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Mucus production, host-microbiome interactions, hormone sensitivity, and innate immune responses modeled in human cervix chips.
Izadifar Z, Cotton J, Chen S, Horvath V, Stejskalova A, Gulati A, LoGrande NT, Budnik B, Shahriar S, Doherty ER, Xie Y, To T, Gilpin SE, Sesay AM, Goyal G, Lebrilla CB, Ingber DE. Izadifar Z, et al. Among authors: to t. Nat Commun. 2024 May 29;15(1):4578. doi: 10.1038/s41467-024-48910-0. Nat Commun. 2024. PMID: 38811586 Free PMC article.
Vaginal microbiome-host interactions modeled in a human vagina-on-a-chip.
Mahajan G, Doherty E, To T, Sutherland A, Grant J, Junaid A, Gulati A, LoGrande N, Izadifar Z, Timilsina SS, Horváth V, Plebani R, France M, Hood-Pishchany I, Rakoff-Nahoum S, Kwon DS, Goyal G, Prantil-Baun R, Ravel J, Ingber DE. Mahajan G, et al. Among authors: to t. Microbiome. 2022 Nov 26;10(1):201. doi: 10.1186/s40168-022-01400-1. Microbiome. 2022. PMID: 36434666 Free PMC article.
Adoptive T cell transfer and host antigen-presenting cell recruitment with cryogel scaffolds promotes long-term protection against solid tumors.
Adu-Berchie K, Brockman JM, Liu Y, To TW, Zhang DKY, Najibi AJ, Binenbaum Y, Stafford A, Dimitrakakis N, Sobral MC, Dellacherie MO, Mooney DJ. Adu-Berchie K, et al. Nat Commun. 2023 Jun 15;14(1):3546. doi: 10.1038/s41467-023-39330-7. Nat Commun. 2023. PMID: 37322053 Free PMC article.
Although adoptive T cell therapy provides the T cell pool needed for immediate tumor debulking, the infused T cells generally have a narrow repertoire for antigen recognition and limited ability for long-term protection. Here, we present a hydrogel that local …
Although adoptive T cell therapy provides the T cell pool needed for immediate tumor debulking, the infused T cells gen …
Surface-Functionalized Microgels as Artificial Antigen-Presenting Cells to Regulate Expansion of T Cells.
Lou J, Meyer C, Vitner EB, Adu-Berchie K, Dacus MT, Bovone G, Chen A, To T, Weitz DA, Mooney DJ. Lou J, et al. Among authors: to t. Adv Mater. 2024 Aug;36(31):e2309860. doi: 10.1002/adma.202309860. Epub 2024 May 29. Adv Mater. 2024. PMID: 38615189
Artificial antigen-presenting cells (aAPCs) are currently used to manufacture T cells for adoptive therapy in cancer treatment, but a readily tunable and modular system can enable both rapid T cell expansion and control over T cell phenotype. Here, it …
Artificial antigen-presenting cells (aAPCs) are currently used to manufacture T cells for adoptive therapy in cancer treatment …
Canadian Spine Society: 24th Annual Scientific Conference, Wednesday, February 28 - Saturday, March 2, Fairmont Chateau Whistler, Whistler, B.C., Canada.
Dionne A, Al-Zakri M, Labelle H, Joncas J, Parent S, Mac-Thiong JM, Miyanji F, Lonner B, Eren A, Cahill P, Parent S, Newton P, Dermott JA, Jaakkimainen L, To T, Bouchard M, Howard A, Lebel DE, Hardy S, Malhotra AK, Dermott J, Thevarajah D, Mathias KDA, Yoon S, Sakhrekar R, Lebel DE, Kim DJ, Hadi A, Doria A, Mitani A, Dermott J, Howard A, Lebel D, Yoon S, Mathias K, Dermott J, Lebel D, Miyanji F, Newton P, Lonner B, Bastrom T, Samdani A, Roy-Beaudry M, Beauséjour M, Imbeault R, Dufresne J, Parent S, Romeo J, Livock H, Smit K, Jarvis J, Tice A, Chan VK, Cho R, Poon S, Skaggs DL, Shumilak GK, Rocos B, Sardi JP, Charalampidis A, Gum J, Lewis SJ, Tretiakov PS, Onafowokan O, Mir J, Das A, Williamson T, Dave P, Imbo B, Lebovic J, Jankowski P, Passias PG, Lewis S, Aljamaan Y, Lenke LG, Smith J, Varshney VP, Sahjpaul R, Paquette S, Osborn J, Pelletier-Roy R, Asmussen M, Birk M, Ludwig T, Nicholls F, Zohar A, Loomans J, Pellise F, Smith JS, Kato S, Sardar Z, Lenke L, Lewis SJ, Abbas A, Toor J, Sahi G, Kovacevic D, Lex J, Miyanji F, Rampersaud R, Perruccio AV, Mahomed N, Canizares M; CSORN Investigators; Rizkallah M, Lebreton MA, Boubez G, Shen J, AlShakfa F, Kamel Y, Osman G, Wang Z,… See abstract for full author list ➔ Dionne A, et al. Among authors: to t. Can J Surg. 2024 Nov 13;67(6suppl1):S17-S76. doi: 10.1503/cjs.011424. Print 2024 Nov-Dec. Can J Surg. 2024. PMID: 39537311 Free PMC article. No abstract available.
An iron-rich subset of macrophages promotes tumor growth through a Bach1-Ednrb axis.
Folkert IW, Molina Arocho WA, To TKJ, Devalaraja S, Molina IS, Shoush J, Mohei H, Zhai L, Akhtar MN, Kochat V, Arslan E, Lazar AJ, Wani K, Israel WP, Zhang Z, Chaluvadi VS, Norgard RJ, Liu Y, Fuller AM, Dang MT, Roses RE, Karakousis GC, Miura JT, Fraker DL, Eisinger-Mathason TSK, Simon MC, Weber K, Tan K, Fan Y, Rai K, Haldar M. Folkert IW, et al. Among authors: to tkj. J Exp Med. 2024 Oct 7;221(10):e20230420. doi: 10.1084/jem.20230420. Epub 2024 Sep 30. J Exp Med. 2024. PMID: 39347789
Sex-related differences in pulmonary vascular volume distribution.
Wright SP, Kirby M, Singh GV, Tan WC, Bourbeau J, Eves ND; CanCOLD Collaborative Research Group. Wright SP, et al. Pulm Circ. 2024 Sep 12;14(3):e12436. doi: 10.1002/pul2.12436. eCollection 2024 Jul. Pulm Circ. 2024. PMID: 39268397 Free PMC article.
844 results