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Post-GWAS multiomic functional investigation of the TNIP1 locus in Alzheimer's disease highlights a potential role for GPX3.
Panyard DJ, Reus LM, Ali M, Liu J, Deming YK, Lu Q, Kollmorgen G, Carboni M, Wild N, Visser PJ, Bertram L, Zetterberg H, Blennow K, Gobom J, Western D, Sung YJ, Carlsson CM, Johnson SC, Asthana S, Cruchaga C, Tijms BM, Engelman CD, Snyder MP. Panyard DJ, et al. Among authors: lu q. Alzheimers Dement. 2024 Jul;20(7):5044-5053. doi: 10.1002/alz.13848. Epub 2024 May 29. Alzheimers Dement. 2024. PMID: 38809917 Free PMC article.
Genetic variants and functional pathways associated with resilience to Alzheimer's disease.
Dumitrescu L, Mahoney ER, Mukherjee S, Lee ML, Bush WS, Engelman CD, Lu Q, Fardo DW, Trittschuh EH, Mez J, Kaczorowski C, Hernandez Saucedo H, Widaman KF, Buckley R, Properzi M, Mormino E, Yang HS, Harrison T, Hedden T, Nho K, Andrews SJ, Tommet D, Hadad N, Sanders RE, Ruderfer DM, Gifford KA, Moore AM, Cambronero F, Zhong X, Raghavan NS, Vardarajan B; Alzheimer’s Disease Neuroimaging Initiative (ADNI); Alzheimer’s Disease Genetics Consortium (ADGC), A4 Study Team; Pericak-Vance MA, Farrer LA, Wang LS, Cruchaga C, Schellenberg G, Cox NJ, Haines JL, Keene CD, Saykin AJ, Larson EB, Sperling RA, Mayeux R, Bennett DA, Schneider JA, Crane PK, Jefferson AL, Hohman TJ. Dumitrescu L, et al. Among authors: lu q. Brain. 2020 Aug 1;143(8):2561-2575. doi: 10.1093/brain/awaa209. Brain. 2020. PMID: 32844198 Free PMC article.
Sex differences in the genetic architecture of cognitive resilience to Alzheimer's disease.
Eissman JM, Dumitrescu L, Mahoney ER, Smith AN, Mukherjee S, Lee ML, Scollard P, Choi SE, Bush WS, Engelman CD, Lu Q, Fardo DW, Trittschuh EH, Mez J, Kaczorowski CC, Hernandez Saucedo H, Widaman KF, Buckley RF, Properzi MJ, Mormino EC, Yang HS, Harrison TM, Hedden T, Nho K, Andrews SJ, Tommet D, Hadad N, Sanders RE, Ruderfer DM, Gifford KA, Zhong X, Raghavan NS, Vardarajan BN; Alzheimer’s Disease Neuroimaging Initiative (ADNI); Alzheimer’s Disease Genetics Consortium (ADGC); A4 Study Team; Pericak-Vance MA, Farrer LA, Wang LS, Cruchaga C, Schellenberg GD, Cox NJ, Haines JL, Keene CD, Saykin AJ, Larson EB, Sperling RA, Mayeux R, Cuccaro ML, Bennett DA, Schneider JA, Crane PK, Jefferson AL, Hohman TJ. Eissman JM, et al. Among authors: lu q. Brain. 2022 Jul 29;145(7):2541-2554. doi: 10.1093/brain/awac177. Brain. 2022. PMID: 35552371 Free PMC article.
Principal components from untargeted cerebrospinal fluid metabolomics associated with Alzheimer's disease biomarkers.
Dong R, Denier-Fields DN, Lu Q, Suridjan I, Kollmorgen G, Wild N, Betthauser TJ, Carlsson CM, Asthana S, Johnson SC, Zetterberg H, Blennow K, Engelman CD. Dong R, et al. Among authors: lu q. Neurobiol Aging. 2022 Sep;117:12-23. doi: 10.1016/j.neurobiolaging.2022.04.009. Epub 2022 May 3. Neurobiol Aging. 2022. PMID: 35640460 Free PMC article.
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