KUS121, a VCP modulator, has an ameliorating effect on acute and chronic heart failure without calcium loading via maintenance of intracellular ATP levels.
Tsuji S, Otani C, Horie T, Watanabe S, Baba O, Sowa N, Ide Y, Kashiwa A, Makiyama T, Imai H, Nakashima Y, Yamasaki T, Xu S, Matsushita K, Suzuki K, Zou F, Kume E, Hasegawa K, Kimura T, Kakizuka A, Ono K.
Tsuji S, et al. Among authors: suzuki k.
Biomed Pharmacother. 2024 Jan;170:115850. doi: 10.1016/j.biopha.2023.115850. Epub 2023 Dec 12.
Biomed Pharmacother. 2024.
PMID: 38091636
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