Wu A - Search Results

1

Discovery and mechanistic study of Imperatorin that inhibits HBsAg expression and cccDNA transcription.

Ren F, Zhao S, He X, Lo H, Wong VKW, Law BYK, Wu A, Zhang J. Ren F, et al. Among authors: wu a. J Med Virol. 2024 May;96(5):e29669. doi: 10.1002/jmv.29669. J Med Virol. 2024. PMID: 38773784

2

Onjisaponin B derived from Radix Polygalae enhances autophagy and accelerates the degradation of mutant α-synuclein and huntingtin in PC-12 cells.

Wu AG, Wong VK, Xu SW, Chan WK, Ng CI, Liu L, Law BY. Wu AG, et al. Int J Mol Sci. 2013 Nov 15;14(11):22618-41. doi: 10.3390/ijms141122618. Int J Mol Sci. 2013. PMID: 24248062 Free PMC article.

3

Identification of novel autophagic Radix Polygalae fraction by cell membrane chromatography and UHPLC-(Q)TOF-MS for degradation of neurodegenerative disease proteins.

Wu AG, Wong VK, Zeng W, Liu L, Law BY. Wu AG, et al. Sci Rep. 2015 Nov 24;5:17199. doi: 10.1038/srep17199. Sci Rep. 2015. PMID: 26598009 Free PMC article.

4

Hederagenin and α-hederin promote degradation of proteins in neurodegenerative diseases and improve motor deficits in MPTP-mice.

Wu AG, Zeng W, Wong VK, Zhu YZ, Lo AC, Liu L, Law BY. Wu AG, et al. Pharmacol Res. 2017 Jan;115:25-44. doi: 10.1016/j.phrs.2016.11.002. Epub 2016 Nov 9. Pharmacol Res. 2017. PMID: 27838509

5

The New Application of UHPLC-DAD-TOF/MS in Identification of Inhibitors on β-Amyloid Fibrillation From Scutellaria baicalensis.

Yu L, Wu AG, Wong VK, Qu LQ, Zhang N, Qin DL, Zeng W, Tang B, Wang HM, Wang Q, Law BY. Yu L, et al. Front Pharmacol. 2019 Mar 18;10:194. doi: 10.3389/fphar.2019.00194. eCollection 2019. Front Pharmacol. 2019. PMID: 30936829 Free PMC article.

6

Polyphyllin VI, a saponin from Trillium tschonoskii Maxim. induces apoptotic and autophagic cell death via the ROS triggered mTOR signaling pathway in non-small cell lung cancer.

Teng JF, Qin DL, Mei QB, Qiu WQ, Pan R, Xiong R, Zhao Y, Law BY, Wong VK, Tang Y, Yu CL, Zhang F, Wu JM, Wu AG. Teng JF, et al. Pharmacol Res. 2019 Sep;147:104396. doi: 10.1016/j.phrs.2019.104396. Epub 2019 Aug 9. Pharmacol Res. 2019. PMID: 31404628

7

Novel steroidal saponin isolated from Trillium tschonoskii maxim. exhibits anti-oxidative effect via autophagy induction in cellular and Caenorhabditis elegans models.

Wu AG, Teng JF, Wong VK, Zhou XG, Qiu WQ, Tang Y, Wu JM, Xiong R, Pan R, Wang YL, Tang B, Ding TY, Yu L, Zeng W, Qin DL, Law BY. Wu AG, et al. Phytomedicine. 2019 Dec;65:153088. doi: 10.1016/j.phymed.2019.153088. Epub 2019 Sep 16. Phytomedicine. 2019. PMID: 31627105

8

Bavachin Protects Human Aortic Smooth Muscle Cells Against β-Glycerophosphate-Mediated Vascular Calcification and Apoptosis via Activation of mTOR-Dependent Autophagy and Suppression of β-Catenin Signaling.

He HQ, Law BYK, Zhang N, Qiu CL, Qu YQ, Wu AG, Han Y, Song Q, Zheng WL, Liu Y, He YZ, Wong VKW. He HQ, et al. Front Pharmacol. 2019 Dec 19;10:1427. doi: 10.3389/fphar.2019.01427. eCollection 2019. Front Pharmacol. 2019. PMID: 31920640 Free PMC article.

9

Polyphyllin VI Induces Caspase-1-Mediated Pyroptosis via the Induction of ROS/NF-κB/NLRP3/GSDMD Signal Axis in Non-Small Cell Lung Cancer.

Teng JF, Mei QB, Zhou XG, Tang Y, Xiong R, Qiu WQ, Pan R, Law BY, Wong VK, Yu CL, Long HA, Xiao XL, Zhang F, Wu JM, Qin DL, Wu AG. Teng JF, et al. Cancers (Basel). 2020 Jan 13;12(1):193. doi: 10.3390/cancers12010193. Cancers (Basel). 2020. PMID: 31941010 Free PMC article.

10

SERCA and P-glycoprotein inhibition and ATP depletion are necessary for celastrol-induced autophagic cell death and collateral sensitivity in multidrug-resistant tumor cells.

Xu SW, Law BYK, Qu SLQ, Hamdoun S, Chen J, Zhang W, Guo JR, Wu AG, Mok SWF, Zhang DW, Xia C, Sugimoto Y, Efferth T, Liu L, Wong VKW. Xu SW, et al. Pharmacol Res. 2020 Mar;153:104660. doi: 10.1016/j.phrs.2020.104660. Epub 2020 Jan 23. Pharmacol Res. 2020. PMID: 31982489

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