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Page 1
Precision immuno-oncology approach for four malignant tumors in siblings with constitutional mismatch repair deficiency syndrome.
Palova H, Das A, Pokorna P, Bajciova V, Pavelka Z, Jezova M, Pal K, Dimayacyac JR, Negm L, Stengs L, Bianchi V, Vejmelkova K, Noskova K, Jarosova M, Mejstrikova S, Mudry P, Kyr M, Merta T, Tinka P, Drabova K, Aulicka S, Jugas R, Tabori U, Slaby O, Sterba J. Palova H, et al. Among authors: slaby o. NPJ Precis Oncol. 2024 May 21;8(1):110. doi: 10.1038/s41698-024-00597-8. NPJ Precis Oncol. 2024. PMID: 38773265 Free PMC article.
Targeted treatment of severe vascular malformations harboring PIK3CA and TEK mutations with alpelisib is highly effective with limited toxicity.
Sterba M, Pokorna P, Faberova R, Pinkova B, Skotakova J, Seehofnerova A, Blatny J, Janigova L, Koskova O, Palova H, Mahdal M, Pazourek L, Jabandziev P, Slaby O, Mudry P, Sterba J. Sterba M, et al. Among authors: slaby o. Sci Rep. 2023 Jun 28;13(1):10499. doi: 10.1038/s41598-023-37468-4. Sci Rep. 2023. PMID: 37380669 Free PMC article.
Optimized procedure for high-throughput transcriptome profiling of small extracellular vesicles isolated from low volume serum samples.
Vychytilova-Faltejskova P, Vilmanova S, Pifkova L, Catela Ivković T, Mᶏdrzyk M, Jugas R, Machackova T, Kotoucek J, Sachlova M, Bohovicova L, Stanek T, Halamkova J, Kiss I, Slaby O. Vychytilova-Faltejskova P, et al. Among authors: slaby o. Clin Chem Lab Med. 2023 Jul 31;62(1):157-167. doi: 10.1515/cclm-2023-0610. Print 2024 Jan 26. Clin Chem Lab Med. 2023. PMID: 37505924 Free article.
Tazemetostat in the therapy of pediatric INI1-negative malignant rhabdoid tumors.
Vejmelkova K, Pokorna P, Noskova K, Faustmannova A, Drabova K, Pavelka Z, Bajciova V, Broz M, Tinka P, Jezova M, Palova H, Kren L, Valik D, Slaby O, Sterba J. Vejmelkova K, et al. Among authors: slaby o. Sci Rep. 2023 Dec 7;13(1):21623. doi: 10.1038/s41598-023-48774-2. Sci Rep. 2023. PMID: 38062114 Free PMC article.
PredictONCO: a web tool supporting decision-making in precision oncology by extending the bioinformatics predictions with advanced computing and machine learning.
Stourac J, Borko S, Khan RT, Pokorna P, Dobias A, Planas-Iglesias J, Mazurenko S, Pinto G, Szotkowska V, Sterba J, Slaby O, Damborsky J, Bednar D. Stourac J, et al. Among authors: slaby o. Brief Bioinform. 2023 Nov 22;25(1):bbad441. doi: 10.1093/bib/bbad441. Brief Bioinform. 2023. PMID: 38066711 Free PMC article.
Personalized dendritic cell vaccine in multimodal individualized combination therapy improves survival in high-risk pediatric cancer patients.
Kyr M, Mudry P, Polaskova K, Dubska LZ, Demlova R, Kubatova J, Hlavackova E, Pilatova KC, Mazanek P, Vejmelkova K, Dusek V, Tinka P, Balaz M, Merta T, Kuttnerova Z, Turekova T, Pavelka Z, Pokorna P, Palova H, Mlnarikova M, Jezova M, Kellnerova R, Kozakova S, Slaby O, Valik D, Sterba J. Kyr M, et al. Among authors: slaby o. Int J Cancer. 2024 Oct 15;155(8):1443-1454. doi: 10.1002/ijc.35062. Epub 2024 Jul 3. Int J Cancer. 2024. PMID: 38958237
A computational workflow for analysis of missense mutations in precision oncology.
Khan RT, Pokorna P, Stourac J, Borko S, Arefiev I, Planas-Iglesias J, Dobias A, Pinto G, Szotkowska V, Sterba J, Slaby O, Damborsky J, Mazurenko S, Bednar D. Khan RT, et al. Among authors: slaby o. J Cheminform. 2024 Jul 29;16(1):86. doi: 10.1186/s13321-024-00876-3. J Cheminform. 2024. PMID: 39075588 Free PMC article.
Real-world performance of integrative clinical genomics in pediatric precision oncology.
Pokorna P, Palova H, Adamcova S, Jugas R, Al Tukmachi D, Kyr M, Knoflickova D, Kozelkova K, Bystry V, Mejstrikova S, Merta T, Trachtova K, Podlipna E, Mudry P, Pavelka Z, Bajciova V, Tinka P, Jarosova M, Ivkovic TC, Madlener S, Pal K, Stepien N, Mayr L, Tichy B, Drabova K, Jezova M, Kozakova S, Vanackova J, Radova L, Steininger K, Haberler C, Gojo J, Sterba J, Slaby O. Pokorna P, et al. Among authors: slaby o. Lab Invest. 2024 Oct 21:102161. doi: 10.1016/j.labinv.2024.102161. Online ahead of print. Lab Invest. 2024. PMID: 39442669 Free article.
359 results