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Page 1
Mutation and cell state compatibility is required and targetable in Ph+ acute lymphoblastic leukemia minimal residual disease.
Winter PS, Ramseier ML, Navia AW, Saksena S, Strouf H, Senhaji N, DenAdel A, Mirza M, An HH, Bilal L, Dennis P, Leahy CS, Shigemori K, Galves-Reyes J, Zhang Y, Powers F, Mulugeta N, Gupta AJ, Calistri N, Van Scoyk A, Jones K, Liu H, Stevenson KE, Ren S, Luskin MR, Couturier CP, Amini AP, Raghavan S, Kimmerling RJ, Stevens MM, Crawford L, Weinstock DM, Manalis SR, Shalek AK, Murakami MA. Winter PS, et al. Among authors: navia aw. bioRxiv [Preprint]. 2024 Jun 10:2024.06.06.597767. doi: 10.1101/2024.06.06.597767. bioRxiv. 2024. PMID: 38915726 Free PMC article. Preprint.
An enhanced IL17 and muted type I interferon nasal epithelial cell state characterizes severe COVID-19 with fungal coinfection.
Ziegler CGK, Owings AH, Galeas-Pena M, Kazer SW, Miao VN, Navia AW, Tang Y, Bromley JD, Lotfy P, Sloan M, Laird H, Williams HB, George M, Drake RS, Pride Y, Abraham GE 3rd, Senitko M, Robinson TO, Diamond G, Lionakis MS, Shalek AK, Ordovas-Montanes J, Horwitz BH, Glover SC. Ziegler CGK, et al. Among authors: navia aw. Microbiol Spectr. 2024 Jun 4;12(6):e0351623. doi: 10.1128/spectrum.03516-23. Epub 2024 Apr 30. Microbiol Spectr. 2024. PMID: 38687064 Free PMC article.
Spatially Resolved Single-Cell Assessment of Pancreatic Cancer Expression Subtypes Reveals Co-expressor Phenotypes and Extensive Intratumoral Heterogeneity.
Williams HL, Dias Costa A, Zhang J, Raghavan S, Winter PS, Kapner KS, Ginebaugh SP, Väyrynen SA, Väyrynen JP, Yuan C, Navia AW, Wang J, Yang A, Bosse TL, Kalekar RL, Lowder KE, Lau MC, Elganainy D, Morales-Oyarvide V, Rubinson DA, Singh H, Perez K, Cleary JM, Clancy TE, Wang J, Mancias JD, Brais LK, Hill ER, Kozak MM, Linehan DC, Dunne RF, Chang DT, Koong AC, Hezel AF, Hahn WC, Shalek AK, Aguirre AJ, Nowak JA, Wolpin BM. Williams HL, et al. Among authors: navia aw. Cancer Res. 2023 Feb 3;83(3):441-455. doi: 10.1158/0008-5472.CAN-22-3050. Cancer Res. 2023. PMID: 36459568 Free PMC article.
Severe COVID-19 is associated with fungal colonization of the nasopharynx and potent induction of IL-17 responses in the nasal epithelium.
Ziegler CGK, Owings AH, Miao VN, Navia AW, Tang Y, Bromley JD, Lotfy P, Sloan M, Laird H, Williams HB, George M, Drake RS, Pride Y, Abraham GE 3rd, Senitko M, Robinson TO, Lionakis MS, Shalek AK, Ordovas-Montanes J, Horwitz BH, Glover SC. Ziegler CGK, et al. Among authors: navia aw. medRxiv [Preprint]. 2022 Oct 26:2022.10.25.22281528. doi: 10.1101/2022.10.25.22281528. medRxiv. 2022. PMID: 36324802 Free PMC article. Preprint.
Microenvironmental Landscape of Human Melanoma Brain Metastases in Response to Immune Checkpoint Inhibition.
Alvarez-Breckenridge C, Markson SC, Stocking JH, Nayyar N, Lastrapes M, Strickland MR, Kim AE, de Sauvage M, Dahal A, Larson JM, Mora JL, Navia AW, Klein RH, Kuter BM, Gill CM, Bertalan M, Shaw B, Kaplan A, Subramanian M, Jain A, Kumar S, Danish H, White M, Shahid O, Pauken KE, Miller BC, Frederick DT, Hebert C, Shaw M, Martinez-Lage M, Frosch M, Wang N, Gerstner E, Nahed BV, Curry WT, Carter B, Cahill DP, Boland GM, Izar B, Davies MA, Sharpe AH, Suvà ML, Sullivan RJ, Brastianos PK, Carter SL. Alvarez-Breckenridge C, et al. Among authors: navia aw. Cancer Immunol Res. 2022 Aug 3;10(8):996-1012. doi: 10.1158/2326-6066.CIR-21-0870. Cancer Immunol Res. 2022. PMID: 35706413 Free PMC article.
Microenvironment drives cell state, plasticity, and drug response in pancreatic cancer.
Raghavan S, Winter PS, Navia AW, Williams HL, DenAdel A, Lowder KE, Galvez-Reyes J, Kalekar RL, Mulugeta N, Kapner KS, Raghavan MS, Borah AA, Liu N, Väyrynen SA, Costa AD, Ng RWS, Wang J, Hill EK, Ragon DY, Brais LK, Jaeger AM, Spurr LF, Li YY, Cherniack AD, Booker MA, Cohen EF, Tolstorukov MY, Wakiro I, Rotem A, Johnson BE, McFarland JM, Sicinska ET, Jacks TE, Sullivan RJ, Shapiro GI, Clancy TE, Perez K, Rubinson DA, Ng K, Cleary JM, Crawford L, Manalis SR, Nowak JA, Wolpin BM, Hahn WC, Aguirre AJ, Shalek AK. Raghavan S, et al. Among authors: navia aw. Cell. 2021 Dec 9;184(25):6119-6137.e26. doi: 10.1016/j.cell.2021.11.017. Cell. 2021. PMID: 34890551 Free PMC article.
Author Correction: Genomic and transcriptomic correlates of immunotherapy response within the tumor microenvironment of leptomeningeal metastases.
Prakadan SM, Alvarez-Breckenridge CA, Markson SC, Kim AE, Klein RH, Nayyar N, Navia AW, Kuter BM, Kolb KE, Bihun I, Mora JL, Bertalan MS, Shaw B, White M, Kaplan A, Stocking JH, Wadsworth MH 2nd, Lee EQ, Chukwueke U, Wang N, Subramanian M, Rotem D, Cahill DP, Adalsteinsson VA, Miller JW, Sullivan RJ, Carter SL, Brastianos PK, Shalek AK. Prakadan SM, et al. Among authors: navia aw. Nat Commun. 2021 Nov 25;12(1):7007. doi: 10.1038/s41467-021-27207-6. Nat Commun. 2021. PMID: 34824235 Free PMC article. No abstract available.
Enteric Coronavirus Infection and Treatment Modeled With an Immunocompetent Human Intestine-On-A-Chip.
Bein A, Kim S, Goyal G, Cao W, Fadel C, Naziripour A, Sharma S, Swenor B, LoGrande N, Nurani A, Miao VN, Navia AW, Ziegler CGK, Montañes JO, Prabhala P, Kim MS, Prantil-Baun R, Rodas M, Jiang A, O'Sullivan L, Tillya G, Shalek AK, Ingber DE. Bein A, et al. Among authors: navia aw. Front Pharmacol. 2021 Oct 25;12:718484. doi: 10.3389/fphar.2021.718484. eCollection 2021. Front Pharmacol. 2021. PMID: 34759819 Free PMC article.
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