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The Peptidoglycan Recognition Protein 1 confers immune evasive properties on pancreatic cancer stem cells.
López-Gil JC, García-Silva S, Ruiz-Cañas L, Navarro D, Palencia-Campos A, Giráldez-Trujillo A, Earl J, Dorado J, Gómez-López G, Monfort-Vengut A, Alcalá S, Gaida MM, García-Mulero S, Cabezas-Sáinz P, Batres-Ramos S, Barreto E, Sánchez-Tomero P, Vallespinós M, Ambler L, Lin ML, Aicher A, García García de Paredes A, de la Pinta C, Sanjuanbenito A, Ruz-Caracuel I, Rodríguez-Garrote M, Guerra C, Carrato A, de Cárcer G, Sánchez L, Nombela-Arrieta C, Espinet E, Sanchez-Arevalo Lobo VJ, Heeschen C, Sainz B Jr. López-Gil JC, et al. Among authors: heeschen c. Gut. 2024 Aug 8;73(9):1489-1508. doi: 10.1136/gutjnl-2023-330995. Gut. 2024. PMID: 38754953 Free PMC article.
LAMC2 marks a tumor-initiating cell population with an aggressive signature in pancreatic cancer.
Cave DD, Buonaiuto S, Sainz B Jr, Fantuz M, Mangini M, Carrer A, Di Domenico A, Iavazzo TT, Andolfi G, Cortina C, Sevillano M, Heeschen C, Colonna V, Corona M, Cucciardi A, Di Guida M, Batlle E, De Luca A, Lonardo E. Cave DD, et al. Among authors: heeschen c. J Exp Clin Cancer Res. 2022 Oct 26;41(1):315. doi: 10.1186/s13046-022-02516-w. J Exp Clin Cancer Res. 2022. PMID: 36289544 Free PMC article.
Bispecific T cell-engager targeting oncofetal chondroitin sulfate induces complete tumor regression and protective immune memory in mice.
Skeltved N, Nordmaj MA, Berendtsen NT, Dagil R, Stormer EMR, Al-Nakouzi N, Jiang K, Aicher A, Heeschen C, Gustavsson T, Choudhary S, Gögenur I, Christensen JP, Theander TG, Daugaard M, Salanti A, Nielsen MA. Skeltved N, et al. Among authors: heeschen c. J Exp Clin Cancer Res. 2023 Apr 28;42(1):106. doi: 10.1186/s13046-023-02655-8. J Exp Clin Cancer Res. 2023. PMID: 37118819 Free PMC article.
A Self-Assembled 3D Model Demonstrates How Stiffness Educates Tumor Cell Phenotypes and Therapy Resistance in Pancreatic Cancer.
Liu Y, Okesola BO, Osuna de la Peña D, Li W, Lin ML, Trabulo S, Tatari M, Lawlor RT, Scarpa A, Wang W, Knight M, Loessner D, Heeschen C, Mata A, Pearce OMT. Liu Y, et al. Among authors: heeschen c. Adv Healthc Mater. 2024 Jul;13(17):e2301941. doi: 10.1002/adhm.202301941. Epub 2024 Mar 22. Adv Healthc Mater. 2024. PMID: 38471128 Free PMC article.
CTC-derived pancreatic cancer models serve as research tools and are suitable for precision medicine approaches.
Tang J, Zheng Q, Wang Q, Zhao Y, Ananthanarayanan P, Reina C, Šabanović B, Jiang K, Yang MH, Meny CC, Wang H, Agerbaek MØ, Clausen TM, Gustavsson T, Wen C, Borghi F, Mellano A, Fenocchio E, Gregorc V, Sapino A, Theander TG, Fu D, Aicher A, Salanti A, Shen B, Heeschen C. Tang J, et al. Among authors: heeschen c. Cell Rep Med. 2024 Sep 17;5(9):101692. doi: 10.1016/j.xcrm.2024.101692. Epub 2024 Aug 19. Cell Rep Med. 2024. PMID: 39163864 Free PMC article.
Pharmacological targeting of the receptor ALK inhibits tumorigenicity and overcomes chemoresistance in pancreatic ductal adenocarcinoma.
Parejo-Alonso B, Royo-García A, Espiau-Romera P, Courtois S, Curiel-García Á, Zagorac S, Villaoslada I, Olive KP, Heeschen C, Sancho P. Parejo-Alonso B, et al. Among authors: heeschen c. Biomed Pharmacother. 2023 Feb;158:114162. doi: 10.1016/j.biopha.2022.114162. Epub 2022 Dec 24. Biomed Pharmacother. 2023. PMID: 36571997 Free article.
Dissecting the role of toll-like receptor 7 in pancreatic cancer.
Stark M, Nicolai M, Tatura M, Keber CU, Kaufmann A, Chung HR, Slater EP, Heeschen C, Lawlor RT, Scarpa A, Bartsch DK, Gress TM, Bauer S, Buchholz M. Stark M, et al. Among authors: heeschen c. Cancer Med. 2023 Apr;12(7):8542-8556. doi: 10.1002/cam4.5606. Epub 2023 Jan 5. Cancer Med. 2023. PMID: 36602302 Free PMC article.
158 results