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Multiparametric senescent cell phenotyping reveals CD24 osteolineage cells as targets of senolytic therapy in the aged murine skeleton.
Doolittle ML, Saul D, Kaur J, Rowsey JL, Vos SJ, Pavelko KD, Farr JN, Monroe DG, Khosla S. Doolittle ML, et al. Among authors: khosla s. bioRxiv [Preprint]. 2023 Jan 13:2023.01.12.523760. doi: 10.1101/2023.01.12.523760. bioRxiv. 2023. Update in: Nat Commun. 2023 Jul 31;14(1):4587. doi: 10.1038/s41467-023-40393-9. PMID: 36711531 Free PMC article. Updated. Preprint.
Reference Intervals for Bone Impact Microindentation in Healthy Adults: A Multi-Centre International Study.
Rufus-Membere P, Holloway-Kew KL, Diez-Perez A, Appelman-Dijkstra NM, Bouxsein ML, Eriksen EF, Farr JN, Khosla S, Kotowicz MA, Nogues X, Rubin M, Pasco JA. Rufus-Membere P, et al. Among authors: khosla s. Calcif Tissue Int. 2023 Mar;112(3):338-349. doi: 10.1007/s00223-022-01047-y. Epub 2023 Feb 2. Calcif Tissue Int. 2023. PMID: 36729139 Free PMC article.
Local senolysis in aged mice only partially replicates the benefits of systemic senolysis.
Farr JN, Saul D, Doolittle ML, Kaur J, Rowsey JL, Vos SJ, Froemming MN, Lagnado AB, Zhu Y, Weivoda M, Ikeno Y, Pignolo RJ, Niedernhofer LJ, Robbins PD, Jurk D, Passos JF, LeBrasseur NK, Tchkonia T, Kirkland JL, Monroe DG, Khosla S. Farr JN, et al. Among authors: khosla s. J Clin Invest. 2023 Apr 17;133(8):e162519. doi: 10.1172/JCI162519. J Clin Invest. 2023. PMID: 36809340 Free PMC article.
In vitro and in vivo effects of zoledronic acid on senescence and senescence-associated secretory phenotype markers.
Samakkarnthai P, Saul D, Zhang L, Aversa Z, Doolittle ML, Sfeir JG, Kaur J, Atkinson EJ, Edwards JR, Russell GG, Pignolo RJ, Kirkland JL, Tchkonia T, Niedernhofer LJ, Monroe DG, Lebrasseur NK, Farr JN, Robbins PD, Khosla S. Samakkarnthai P, et al. Among authors: khosla s. Aging (Albany NY). 2023 May 7;15(9):3331-3355. doi: 10.18632/aging.204701. Epub 2023 May 7. Aging (Albany NY). 2023. PMID: 37154858 Free PMC article.
Senotherapeutic drug treatment ameliorates chemotherapy-induced cachexia.
Englund DA, Jolliffe AM, Hanson GJ, Aversa Z, Zhang X, Jiang X, White TA, Zhang L, Monroe DG, Robbins PD, Niedernhofer LJ, Kamenecka TM, Khosla S, LeBrasseur NK. Englund DA, et al. Among authors: khosla s. JCI Insight. 2024 Jan 23;9(2):e169512. doi: 10.1172/jci.insight.169512. JCI Insight. 2024. PMID: 38051584 Free PMC article.
Marrow Adipocyte Senescence in the Pathogenesis of Bone Loss.
Froemming MN, Khosla S, Farr JN. Froemming MN, et al. Among authors: khosla s. Curr Osteoporos Rep. 2024 Aug;22(4):378-386. doi: 10.1007/s11914-024-00875-1. Epub 2024 Jun 3. Curr Osteoporos Rep. 2024. PMID: 38829487 Review.
Guidelines for minimal information on cellular senescence experimentation in vivo.
Ogrodnik M, Carlos Acosta J, Adams PD, d'Adda di Fagagna F, Baker DJ, Bishop CL, Chandra T, Collado M, Gil J, Gorgoulis V, Gruber F, Hara E, Jansen-Dürr P, Jurk D, Khosla S, Kirkland JL, Krizhanovsky V, Minamino T, Niedernhofer LJ, Passos JF, Ring NAR, Redl H, Robbins PD, Rodier F, Scharffetter-Kochanek K, Sedivy JM, Sikora E, Witwer K, von Zglinicki T, Yun MH, Grillari J, Demaria M. Ogrodnik M, et al. Among authors: khosla s. Cell. 2024 Aug 8;187(16):4150-4175. doi: 10.1016/j.cell.2024.05.059. Cell. 2024. PMID: 39121846 Free article. Review.
957 results