Increased plasma MMP9 in integrin alpha1-null mice enhances lung metastasis of colon carcinoma cells.
Chen X, Su Y, Fingleton B, Acuff H, Matrisian LM, Zent R, Pozzi A.
Chen X, et al. Among authors: pozzi a.
Int J Cancer. 2005 Aug 10;116(1):52-61. doi: 10.1002/ijc.20997.
Int J Cancer. 2005.
PMID: 15756690
To determine which effect of elevated MMP levels dominates in the progression of metastatic cancer, experimental lung metastasis assays were performed in integrin alpha1-null mice, a genetic model for increased plasma levels of MMP9 and MMP9-generated angiostatin (Pozzi …
To determine which effect of elevated MMP levels dominates in the progression of metastatic cancer, experimental lung metastasis assays were …