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Structural basis of human NOX5 activation.
Cui C, Jiang M, Jain N, Das S, Lo YH, Kermani AA, Pipatpolkai T, Sun J. Cui C, et al. Among authors: das s. Nat Commun. 2024 May 11;15(1):3994. doi: 10.1038/s41467-024-48467-y. Nat Commun. 2024. PMID: 38734761 Free PMC article.
Selective CK1α degraders exert antiproliferative activity against a broad range of human cancer cell lines.
Nishiguchi G, Mascibroda LG, Young SM, Caine EA, Abdelhamed S, Kooijman JJ, Miller DJ, Das S, McGowan K, Mayasundari A, Shi Z, Barajas JM, Hiltenbrand R, Aggarwal A, Chang Y, Mishra V, Narina S, Thomas M, Loughran AJ, Kalathur R, Yu K, Zhou S, Wang X, High AA, Peng J, Pruett-Miller SM, Daniels DL, Urh M, Shelat AA, Mullighan CG, Riching KM, Zaman GJR, Fischer M, Klco JM, Rankovic Z. Nishiguchi G, et al. Among authors: das s. Nat Commun. 2024 Jan 16;15(1):482. doi: 10.1038/s41467-024-44698-1. Nat Commun. 2024. PMID: 38228616 Free PMC article.
Identification of Potent, Selective, and Orally Bioavailable Small-Molecule GSPT1/2 Degraders from a Focused Library of Cereblon Modulators.
Nishiguchi G, Keramatnia F, Min J, Chang Y, Jonchere B, Das S, Actis M, Price J, Chepyala D, Young B, McGowan K, Slavish PJ, Mayasundari A, Jarusiewicz JA, Yang L, Li Y, Fu X, Garrett SH, Papizan JB, Kodali K, Peng J, Pruett Miller SM, Roussel MF, Mullighan C, Fischer M, Rankovic Z. Nishiguchi G, et al. Among authors: das s. J Med Chem. 2021 Jun 10;64(11):7296-7311. doi: 10.1021/acs.jmedchem.0c01313. Epub 2021 May 27. J Med Chem. 2021. PMID: 34042448 Free PMC article.
Spectinamides: a new class of semisynthetic antituberculosis agents that overcome native drug efflux.
Lee RE, Hurdle JG, Liu J, Bruhn DF, Matt T, Scherman MS, Vaddady PK, Zheng Z, Qi J, Akbergenov R, Das S, Madhura DB, Rathi C, Trivedi A, Villellas C, Lee RB, Rakesh, Waidyarachchi SL, Sun D, McNeil MR, Ainsa JA, Boshoff HI, Gonzalez-Juarrero M, Meibohm B, Böttger EC, Lenaerts AJ. Lee RE, et al. Among authors: das s. Nat Med. 2014 Feb;20(2):152-158. doi: 10.1038/nm.3458. Epub 2014 Jan 26. Nat Med. 2014. PMID: 24464186 Free PMC article.
Synthesis and evaluation of colletoic acid core derivatives.
Ling T, Gautam LN, Griffith E, Das S, Lang W, Shadrick WR, Shelat A, Lee R, Rivas F. Ling T, et al. Among authors: das s. Eur J Med Chem. 2016 Mar 3;110:126-32. doi: 10.1016/j.ejmech.2016.01.027. Epub 2016 Jan 20. Eur J Med Chem. 2016. PMID: 26820555
Novel vitexin-inspired scaffold against leukemia.
Ling T, Lang W, Feng X, Das S, Maier J, Jeffries C, Shelat A, Rivas F. Ling T, et al. Among authors: das s. Eur J Med Chem. 2018 Feb 25;146:501-510. doi: 10.1016/j.ejmech.2018.01.004. Epub 2018 Jan 31. Eur J Med Chem. 2018. PMID: 29407975
Evaluating and evolving a screening library in academia: the St Jude approach.
Nishiguchi G, Das S, Ochoada J, Long H, Lee RE, Rankovic Z, Shelat AA. Nishiguchi G, et al. Among authors: das s. Drug Discov Today. 2021 Apr;26(4):1060-1069. doi: 10.1016/j.drudis.2021.01.005. Epub 2021 Jan 14. Drug Discov Today. 2021. PMID: 33453364 Free PMC article. Review.
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