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Structural transitions enable interleukin-18 maturation and signaling.
Dong Y, Bonin JP, Devant P, Liang Z, Sever AIM, Mintseris J, Aramini JM, Du G, Gygi SP, Kagan JC, Kay LE, Wu H. Dong Y, et al. Among authors: mintseris j. Immunity. 2024 Jul 9;57(7):1533-1548.e10. doi: 10.1016/j.immuni.2024.04.015. Epub 2024 May 10. Immunity. 2024. PMID: 38733997
Large-scale characterization of drug mechanism of action using proteome-wide thermal shift assays.
Van Vranken JG, Li J, Mintseris J, Wei TY, Sniezek CM, Gadzuk-Shea M, Gygi SP, Schweppe DK. Van Vranken JG, et al. Among authors: mintseris j. bioRxiv [Preprint]. 2024 Aug 14:2024.01.26.577428. doi: 10.1101/2024.01.26.577428. bioRxiv. 2024. Update in: Elife. 2024 Nov 11;13:RP95595. doi: 10.7554/eLife.95595 PMID: 38328090 Free PMC article. Updated. Preprint.
The relaxin receptor RXFP1 signals through a mechanism of autoinhibition.
Erlandson SC, Rawson S, Osei-Owusu J, Brock KP, Liu X, Paulo JA, Mintseris J, Gygi SP, Marks DS, Cong X, Kruse AC. Erlandson SC, et al. Among authors: mintseris j. Nat Chem Biol. 2023 Aug;19(8):1013-1021. doi: 10.1038/s41589-023-01321-6. Epub 2023 Apr 20. Nat Chem Biol. 2023. PMID: 37081311 Free PMC article.
DPP9 sequesters the C terminus of NLRP1 to repress inflammasome activation.
Hollingsworth LR, Sharif H, Griswold AR, Fontana P, Mintseris J, Dagbay KB, Paulo JA, Gygi SP, Bachovchin DA, Wu H. Hollingsworth LR, et al. Among authors: mintseris j. Nature. 2021 Apr;592(7856):778-783. doi: 10.1038/s41586-021-03350-4. Epub 2021 Mar 17. Nature. 2021. PMID: 33731932 Free PMC article.
Improved Monoisotopic Mass Estimation for Deeper Proteome Coverage.
Rad R, Li J, Mintseris J, O'Connell J, Gygi SP, Schweppe DK. Rad R, et al. Among authors: mintseris j. J Proteome Res. 2021 Jan 1;20(1):591-598. doi: 10.1021/acs.jproteome.0c00563. Epub 2020 Nov 16. J Proteome Res. 2021. PMID: 33190505
37 results