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Position-specific N- and O-glycosylation of the reactive center loop impacts neutrophil elastase-mediated proteolysis of corticosteroid-binding globulin.
Chernykh A, Abrahams JL, Grant OC, Kambanis L, Sumer-Bayraktar Z, Ugonotti J, Kawahara R, Corcilius L, Payne RJ, Woods RJ, Thaysen-Andersen M. Chernykh A, et al. Among authors: payne rj. J Biol Chem. 2024 Jan;300(1):105519. doi: 10.1016/j.jbc.2023.105519. Epub 2023 Nov 30. J Biol Chem. 2024. PMID: 38042488 Free PMC article.
Serum albumin binding knob domains engineered within a VH framework III bispecific antibody format and as chimeric peptides.
Adams R, Joyce C, Kuravskiy M, Harrison K, Ahdash Z, Balmforth M, Chia K, Marceddu C, Coates M, Snowden J, Goursaud E, Ménochet K, van den Elsen J, Payne RJ, Lawson ADG, Scott-Tucker A, Macpherson A. Adams R, et al. Among authors: payne rj. Front Immunol. 2023 May 12;14:1170357. doi: 10.3389/fimmu.2023.1170357. eCollection 2023. Front Immunol. 2023. PMID: 37251411 Free PMC article.
Clp-targeting BacPROTACs impair mycobacterial proteostasis and survival.
Hoi DM, Junker S, Junk L, Schwechel K, Fischel K, Podlesainski D, Hawkins PME, van Geelen L, Kaschani F, Leodolter J, Morreale FE, Kleine S, Guha S, Rumpel K, Schmiedel VM, Weinstabl H, Meinhart A, Payne RJ, Kaiser M, Hartl M, Boehmelt G, Kazmaier U, Kalscheuer R, Clausen T. Hoi DM, et al. Among authors: payne rj. Cell. 2023 May 11;186(10):2176-2192.e22. doi: 10.1016/j.cell.2023.04.009. Epub 2023 May 2. Cell. 2023. PMID: 37137307 Free article.
Exploiting Hydrophobic Amino Acid Scanning to Develop Cyclic Peptide Inhibitors of the SARS-CoV-2 Main Protease with Antiviral Activity.
Harrison K, Carlos PW, Ullrich S, Aggarwal A, Johansen-Leete J, Sasi VM, Barter I, Maxwell JWC, Bedding MJ, Larance M, Turville S, Norman A, Jackson CJ, Nitsche C, Payne RJ. Harrison K, et al. Among authors: payne rj. Chemistry. 2024 Aug 6;30(44):e202401606. doi: 10.1002/chem.202401606. Epub 2024 Jul 17. Chemistry. 2024. PMID: 38801240
388 results