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Spatial transcriptomic analysis reveals local effects of intratumoral fusobacterial infection on DNA damage and immune signaling in rectal cancer.
Duggan WP, Kisakol B, Woods I, Azimi M, Dussmann H, Fay J, O'Grady T, Maguire B, Reynolds IS, Salvucci M, Slade DJ, McNamara DA, Burke JP, Prehn JHM. Duggan WP, et al. Gut Microbes. 2024 Jan-Dec;16(1):2350149. doi: 10.1080/19490976.2024.2350149. Epub 2024 May 6. Gut Microbes. 2024. PMID: 38709233 Free PMC article.
Multiplexed Immunofluorescence Imaging Reveals an Immune-Rich Tumor Microenvironment in Mucinous Rectal Cancer Characterized by Increased Lymphocyte Infiltration and Enhanced Programmed Cell Death Protein 1 Expression.
Duggan WP, Kisakol B, O'Connell E, Matveeva A, O'Grady T, McDonough E, Lindner AU, McNamara D, Longley D, Ginty F, Burke JP, Prehn JHM. Duggan WP, et al. Dis Colon Rectum. 2023 Jul 1;66(7):914-922. doi: 10.1097/DCR.0000000000002624. Epub 2022 Nov 17. Dis Colon Rectum. 2023. PMID: 36525395 Free PMC article.
Increased Fusobacterium tumoural abundance affects immunogenicity in mucinous colorectal cancer and may be associated with improved clinical outcome.
Duggan WP, Salvucci M, Kisakol B, Lindner AU, Reynolds IS, Dussmann H, Fay J, O'Grady T, Longley DB, Ginty F, Mc Donough E, Slade DJ, Burke JP, Prehn JHM. Duggan WP, et al. J Mol Med (Berl). 2023 Jul;101(7):829-841. doi: 10.1007/s00109-023-02324-5. Epub 2023 May 12. J Mol Med (Berl). 2023. PMID: 37171483 Free PMC article.
23 results