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BTK drives neutrophil activation for sterilizing antifungal immunity.
Desai JV, Zarakas MA, Wishart AL, Roschewski M, Aufiero MA, Donkó Á, Wigerblad G, Shlezinger N, Plate M, James MR, Lim JK, Uzel G, Bergerson JR, Fuss I, Cramer RA, Franco LM, Clark ES, Khan WN, Yamanaka D, Chamilos G, El-Benna J, Kaplan MJ, Staudt LM, Leto TL, Holland SM, Wilson WH, Hohl TM, Lionakis MS. Desai JV, et al. Among authors: el benna j. J Clin Invest. 2024 May 2;134(12):e176142. doi: 10.1172/JCI176142. Online ahead of print. J Clin Invest. 2024. PMID: 38696257 Free PMC article.
AMPK activation by metformin protects against pulmonary hypertension in rats and relaxes isolated human pulmonary artery.
Abdelazeem H, Tu L, Thuillet R, Ottaviani M, Boulfrad A, Beck T, Senbel A, Mani S, Castier Y, Guyard A, Tran-Dinh A, El-Benna J, Longrois D, Silverstein AM, Guignabert C, Norel X. Abdelazeem H, et al. Among authors: el benna j. Eur J Pharmacol. 2023 May 5;946:175579. doi: 10.1016/j.ejphar.2023.175579. Epub 2023 Mar 11. Eur J Pharmacol. 2023. PMID: 36914083
Constitutive and induced forms of membrane-bound proteinase 3 interact with antineutrophil cytoplasmic antibodies and promote immune activation of neutrophils.
Carla Guarino, Seren S, Lemoine R, Hummel AM, Margotin JE, El-Benna J, Hoarau C, Specks U, Jenne DE, Korkmaz B. Carla Guarino, et al. Among authors: el benna j. J Biol Chem. 2023 Apr;299(4):103072. doi: 10.1016/j.jbc.2023.103072. Epub 2023 Feb 26. J Biol Chem. 2023. PMID: 36849007 Free PMC article.
182 results