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Page 1
A 4-gene prognostic index for enhancing acute myeloid leukaemia survival prediction.
Ortiz Rojas CA, Pereira-Martins DA, Bellido More CC, Sternadt D, Weinhäuser I, Hilberink JR, Coelho-Silva JL, Thomé CH, Ferreira GA, Ammatuna E, Huls G, Valk PJ, Schuringa JJ, Rego EM. Ortiz Rojas CA, et al. Among authors: rego em. Br J Haematol. 2024 Jun;204(6):2287-2300. doi: 10.1111/bjh.19472. Epub 2024 Apr 23. Br J Haematol. 2024. PMID: 38651345
The expression of DeltaNTP73, TATP73 and TP53 genes in acute myeloid leukaemia is associated with recurrent cytogenetic abnormalities and in vitro susceptibility to cytarabine cytotoxicity.
Lucena-Araujo AR, Panepucci RA, dos Santos GA, Jácomo RH, Santana-Lemos BA, Lima AS, Garcia AB, Araújo AG, Falcão RP, Rego EM. Lucena-Araujo AR, et al. Among authors: rego em. Br J Haematol. 2008 Jul;142(1):74-8. doi: 10.1111/j.1365-2141.2008.07160.x. Epub 2008 Apr 17. Br J Haematol. 2008. PMID: 18422993 Free article.
The presence of CD56/CD16 in T-cell acute lymphoblastic leukaemia correlates with the expression of cytotoxic molecules and is associated with worse response to treatment.
Dalmazzo LF, Jácomo RH, Marinato AF, Figueiredo-Pontes LL, Cunha RL, Garcia AB, Rego EM, Falcão RP. Dalmazzo LF, et al. Among authors: rego em. Br J Haematol. 2009 Jan;144(2):223-9. doi: 10.1111/j.1365-2141.2008.07457.x. Epub 2008 Nov 11. Br J Haematol. 2009. PMID: 19016721 Free article.
Halofuginone has anti-proliferative effects in acute promyelocytic leukemia by modulating the transforming growth factor beta signaling pathway.
de Figueiredo-Pontes LL, Assis PA, Santana-Lemos BA, Jácomo RH, Lima AS, Garcia AB, Thomé CH, Araújo AG, Panepucci RA, Zago MA, Nagler A, Falcão RP, Rego EM. de Figueiredo-Pontes LL, et al. Among authors: rego em. PLoS One. 2011;6(10):e26713. doi: 10.1371/journal.pone.0026713. Epub 2011 Oct 28. PLoS One. 2011. PMID: 22053203 Free PMC article.
Linker for activation of T-cell family member2 (LAT2) a lipid raft adaptor protein for AKT signaling, is an early mediator of alkylphospholipid anti-leukemic activity.
Thomé CH, dos Santos GA, Ferreira GA, Scheucher PS, Izumi C, Leopoldino AM, Simão AM, Ciancaglini P, de Oliveira KT, Chin A, Hanash SM, Falcão RP, Rego EM, Greene LJ, Faça VM. Thomé CH, et al. Among authors: rego em. Mol Cell Proteomics. 2012 Dec;11(12):1898-912. doi: 10.1074/mcp.M112.019661. Epub 2012 Sep 22. Mol Cell Proteomics. 2012. PMID: 23001822 Free PMC article.
Disrupting membrane raft domains by alkylphospholipids.
Gomide AB, Thomé CH, dos Santos GA, Ferreira GA, Faça VM, Rego EM, Greene LJ, Stabeli RG, Ciancaglini P, Itri R. Gomide AB, et al. Among authors: rego em. Biochim Biophys Acta. 2013 May;1828(5):1384-9. doi: 10.1016/j.bbamem.2013.01.017. Epub 2013 Feb 1. Biochim Biophys Acta. 2013. PMID: 23376656 Free article.
Prognostic impact of KMT2E transcript levels on outcome of patients with acute promyelocytic leukaemia treated with all-trans retinoic acid and anthracycline-based chemotherapy: an International Consortium on Acute Promyelocytic Leukaemia study.
Lucena-Araujo AR, Kim HT, Jacomo RH, Melo RA, Bittencourt R, Pasquini R, Pagnano K, Fagundes EM, de Lourdes Chauffaille M, Chiattone CS, Lima AS, Kwaan HC, Gallagher R, Niemeyer CM, Schrier SL, Tallman MS, Grimwade D, Ganser A, Berliner N, Ribeiro RC, Lo-Coco F, Löwenberg B, Sanz MA, Rego EM. Lucena-Araujo AR, et al. Among authors: rego em. Br J Haematol. 2014 Aug;166(4):540-9. doi: 10.1111/bjh.12921. Epub 2014 May 3. Br J Haematol. 2014. PMID: 24796963 Free article.
High ΔNp73/TAp73 ratio is associated with poor prognosis in acute promyelocytic leukemia.
Lucena-Araujo AR, Kim HT, Thomé C, Jacomo RH, Melo RA, Bittencourt R, Pasquini R, Pagnano K, Glória AB, Chauffaille Mde L, Athayde M, Chiattone CS, Mito I, Bendlin R, Souza C, Bortolheiro C, Coelho-Silva JL, Schrier SL, Tallman MS, Grimwade D, Ganser A, Berliner N, Ribeiro RC, Lo-Coco F, Löwenberg B, Sanz MA, Rego EM. Lucena-Araujo AR, et al. Among authors: rego em. Blood. 2015 Nov 12;126(20):2302-6. doi: 10.1182/blood-2015-01-623330. Epub 2015 Oct 1. Blood. 2015. PMID: 26429976 Free PMC article. Clinical Trial.
200 results