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Page 1
Synaptic gene expression changes in frontotemporal dementia due to the MAPT 10+16 mutation.
Dando O, McGeachan R, McQueen J, Baxter P, Rockley N, McAlister H, Prasad A, He X, King D, Rose J, Jones PB, Tulloch J, Chandran S, Smith C, Hardingham G, Spires-Jones TL. Dando O, et al. Among authors: spires jones tl. medRxiv [Preprint]. 2024 Apr 12:2024.04.09.24305501. doi: 10.1101/2024.04.09.24305501. medRxiv. 2024. Update in: Neuropathol Appl Neurobiol. 2024 Aug;50(4):e13006. doi: 10.1111/nan.13006. PMID: 38645146 Free PMC article. Updated. Preprint.
Tau pathophysiology in neurodegeneration: a tangled issue.
Spires-Jones TL, Stoothoff WH, de Calignon A, Jones PB, Hyman BT. Spires-Jones TL, et al. Trends Neurosci. 2009 Mar;32(3):150-9. doi: 10.1016/j.tins.2008.11.007. Epub 2009 Jan 21. Trends Neurosci. 2009. PMID: 19162340 Review.
Amyloid Beta and Tau Cooperate to Cause Reversible Behavioral and Transcriptional Deficits in a Model of Alzheimer's Disease.
Pickett EK, Herrmann AG, McQueen J, Abt K, Dando O, Tulloch J, Jain P, Dunnett S, Sohrabi S, Fjeldstad MP, Calkin W, Murison L, Jackson RJ, Tzioras M, Stevenson A, d'Orange M, Hooley M, Davies C, Colom-Cadena M, Anton-Fernandez A, King D, Oren I, Rose J, McKenzie CA, Allison E, Smith C, Hardt O, Henstridge CM, Hardingham GE, Spires-Jones TL. Pickett EK, et al. Cell Rep. 2019 Dec 10;29(11):3592-3604.e5. doi: 10.1016/j.celrep.2019.11.044. Cell Rep. 2019. PMID: 31825838 Free PMC article.
Comparative profiling of the synaptic proteome from Alzheimer's disease patients with focus on the APOE genotype.
Hesse R, Hurtado ML, Jackson RJ, Eaton SL, Herrmann AG, Colom-Cadena M, Tzioras M, King D, Rose J, Tulloch J, McKenzie CA, Smith C, Henstridge CM, Lamont D, Wishart TM, Spires-Jones TL. Hesse R, et al. Acta Neuropathol Commun. 2019 Dec 20;7(1):214. doi: 10.1186/s40478-019-0847-7. Acta Neuropathol Commun. 2019. PMID: 31862015 Free PMC article.
Reactive astrocytes acquire neuroprotective as well as deleterious signatures in response to Tau and Aß pathology.
Jiwaji Z, Tiwari SS, Avilés-Reyes RX, Hooley M, Hampton D, Torvell M, Johnson DA, McQueen J, Baxter P, Sabari-Sankar K, Qiu J, He X, Fowler J, Febery J, Gregory J, Rose J, Tulloch J, Loan J, Story D, McDade K, Smith AM, Greer P, Ball M, Kind PC, Matthews PM, Smith C, Dando O, Spires-Jones TL, Johnson JA, Chandran S, Hardingham GE. Jiwaji Z, et al. Nat Commun. 2022 Jan 10;13(1):135. doi: 10.1038/s41467-021-27702-w. Nat Commun. 2022. PMID: 35013236 Free PMC article.
154 results