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Correction: A novel oncogenic BTK isoform is overexpressed in colon cancers and required for RAS-mediated transformation.
Grassilli E, Pisano F, Cialdella A, Bonomo S, Missaglia C, Cerrito MG, Masiero L, Ianzano L, Giordano F, Cicirelli V, Narloch R, D'Amato F, Noli B, Ferri GL, Leone BE, Stanta G, Bonin S, Helin K, Giovannoni R, Lavitrano M. Grassilli E, et al. Among authors: helin k. Oncogene. 2024 May;43(22):1726. doi: 10.1038/s41388-024-03037-w. Oncogene. 2024. PMID: 38637670 Free PMC article. No abstract available.
Inhibition of TOPORS ubiquitin ligase augments the efficacy of DNA hypomethylating agents through DNMT1 stabilization.
Kaito S, Aoyama K, Oshima M, Tsuchiya A, Miyota M, Yamashita M, Koide S, Nakajima-Takagi Y, Kozuka-Hata H, Oyama M, Yogo T, Yabushita T, Ito R, Ueno M, Hirao A, Tohyama K, Li C, Kawabata KC, Yamaguchi K, Furukawa Y, Kosako H, Yoshimi A, Goyama S, Nannya Y, Ogawa S, Agger K, Helin K, Yamazaki S, Koseki H, Doki N, Harada Y, Harada H, Nishiyama A, Nakanishi M, Iwama A. Kaito S, et al. Among authors: helin k. Nat Commun. 2024 Aug 28;15(1):7359. doi: 10.1038/s41467-024-50498-4. Nat Commun. 2024. PMID: 39198387 Free PMC article.
Epigenetic and oncogenic inhibitors cooperatively drive differentiation and kill KRAS-mutant colorectal cancers.
Loi P, Schade AE, Rodriguez CL, Krishnan A, Perurena N, Nguyen VTM, Xu Y, Watanabe M, Davis RA, Gardner A, Pilla NF, Mattioli K, Popow O, Gunduz N, Lannagan TRM, Fitzgerald S, Sicinska ET, Lin JR, Tan W, Brais LK, Haigis KM, Giannakis M, Ng K, Santagata S, Helin K, Sansom OJ, Cichowski K. Loi P, et al. Among authors: helin k. Cancer Discov. 2024 Aug 12. doi: 10.1158/2159-8290.CD-23-0866. Online ahead of print. Cancer Discov. 2024. PMID: 39121480
Roles of H3K4 methylation in biology and disease.
Wang H, Helin K. Wang H, et al. Among authors: helin k. Trends Cell Biol. 2024 Jun 21:S0962-8924(24)00115-6. doi: 10.1016/j.tcb.2024.06.001. Online ahead of print. Trends Cell Biol. 2024. PMID: 38909006 Free article. Review.
TAK1 inhibition leads to RIPK1-dependent apoptosis in immune-activated cancers.
Damhofer H, Tatar T, Southgate B, Scarneo S, Agger K, Shlyueva D, Uhrbom L, Morrison GM, Hughes PF, Haystead T, Pollard SM, Helin K. Damhofer H, et al. Among authors: helin k. Cell Death Dis. 2024 Apr 17;15(4):273. doi: 10.1038/s41419-024-06654-1. Cell Death Dis. 2024. PMID: 38632238 Free PMC article.
RIO-kinase 2 is essential for hematopoiesis.
Messling JE, Peña-Rømer I, Moroni AS, Bruestl S, Helin K. Messling JE, et al. Among authors: helin k. PLoS One. 2024 Apr 2;19(4):e0300623. doi: 10.1371/journal.pone.0300623. eCollection 2024. PLoS One. 2024. PMID: 38564577 Free PMC article.
311 results