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Page 1
Evaluation of Gremlin-1 as a therapeutic target in metabolic dysfunction-associated steatohepatitis.
Horn P, Norlin J, Almholt K, Viuff BM, Galsgaard ED, Hald A, Zosel F, Demuth H, Poulsen S, Norby PL, Rasch MG, Vyberg M, Fleckner J, Werge MP, Gluud LL, Rink MR, Shepherd E, Northall E, Lalor PF, Weston CJ, Fog-Tonnesen M, Newsome PN. Horn P, et al. Among authors: werge mp. Elife. 2024 Oct 3;13:RP95185. doi: 10.7554/eLife.95185. Elife. 2024. PMID: 39361025 Free PMC article.
Hepatic steatosis and not type 2 diabetes, body mass index, or hepatic fibrosis associates with hyperglucagonemia in individuals with steatotic liver disease.
Kjeldsen SAS, Werge MP, Grandt J, Richter MM, Thing M, Hetland LE, Rashu EB, Jensen AH, Winther-Sørensen M, Kellemann JS, Holst JJ, Junker AE, Serizawa RR, Vyberg M, Gluud LL, Wewer Albrechtsen NJ. Kjeldsen SAS, et al. Among authors: werge mp. Am J Physiol Gastrointest Liver Physiol. 2024 Oct 1;327(4):G558-G570. doi: 10.1152/ajpgi.00147.2024. Epub 2024 Aug 6. Am J Physiol Gastrointest Liver Physiol. 2024. PMID: 39104323
Development of a novel non-invasive biomarker panel for hepatic fibrosis in MASLD.
Verschuren L, Mak AL, van Koppen A, Özsezen S, Difrancesco S, Caspers MPM, Snabel J, van der Meer D, van Dijk AM, Rashu EB, Nabilou P, Werge MP, van Son K, Kleemann R, Kiliaan AJ, Hazebroek EJ, Boonstra A, Brouwer WP, Doukas M, Gupta S, Kluft C, Nieuwdorp M, Verheij J, Gluud LL, Holleboom AG, Tushuizen ME, Hanemaaijer R. Verschuren L, et al. Among authors: werge mp. Nat Commun. 2024 May 29;15(1):4564. doi: 10.1038/s41467-024-48956-0. Nat Commun. 2024. PMID: 38811591 Free PMC article.
Patients with autoimmune liver disease have glucose disturbances that mechanistically differ from steatotic liver disease.
Jensen AH, Ytting H, Werge MP, Rashu EB, Hetland LE, Thing M, Nabilou P, Burisch J, Bojsen-Møller KN, Junker AE, Hobolth L, Mortensen C, Tofteng F, Bendtsen F, Møller S, Vyberg M, Serizawa RR, Gluud LL, Wewer Albrechtsen NJ. Jensen AH, et al. Among authors: werge mp. Am J Physiol Gastrointest Liver Physiol. 2024 Jun 1;326(6):G736-G746. doi: 10.1152/ajpgi.00047.2024. Epub 2024 Apr 16. Am J Physiol Gastrointest Liver Physiol. 2024. PMID: 38625142
Neprilysin activity is increased in metabolic dysfunction-associated steatotic liver disease and normalizes after bariatric surgery or GLP-1 therapy.
Kjeldsen SAS, Gluud LL, Werge MP, Pedersen JS, Bendtsen F, Alexiadou K, Tan T, Torekov SS, Iepsen EW, Jensen NJ, Richter MM, Goetze JP, Rungby J, Hartmann B, Holst JJ, Holst B, Holt J, Gustafsson F, Madsbad S, Svane MS, Bojsen-Møller KN, Wewer Albrechtsen NJ. Kjeldsen SAS, et al. Among authors: werge mp. iScience. 2023 Oct 12;26(11):108190. doi: 10.1016/j.isci.2023.108190. eCollection 2023 Nov 17. iScience. 2023. PMID: 37953952 Free PMC article.
21 results