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Tumor Biomechanics Alters Metastatic Dissemination of Triple Negative Breast Cancer via Rewiring Fatty Acid Metabolism.
Filipe EC, Velayuthar S, Philp A, Nobis M, Latham SL, Parker AL, Murphy KJ, Wyllie K, Major GS, Contreras O, Mok ETY, Enriquez RF, McGowan S, Feher K, Quek LE, Hancock SE, Yam M, Tran E, Setargew YFI, Skhinas JN, Chitty JL, Phimmachanh M, Han JZR, Cadell AL, Papanicolaou M, Mahmodi H, Kiedik B, Junankar S, Ross SE, Lam N, Coulson R, Yang J, Zaratzian A, Da Silva AM, Tayao M, Chin IL, Cazet A, Kansara M, Segara D, Parker A, Hoy AJ, Harvey RP, Bogdanovic O, Timpson P, Croucher DR, Lim E, Swarbrick A, Holst J, Turner N, Choi YS, Kabakova IV, Philp A, Cox TR. Filipe EC, et al. Among authors: yang j. Adv Sci (Weinh). 2024 Jun;11(23):e2307963. doi: 10.1002/advs.202307963. Epub 2024 Apr 11. Adv Sci (Weinh). 2024. PMID: 38602451 Free PMC article.
ID4 controls mammary stem cells and marks breast cancers with a stem cell-like phenotype.
Junankar S, Baker LA, Roden DL, Nair R, Elsworth B, Gallego-Ortega D, Lacaze P, Cazet A, Nikolic I, Teo WS, Yang J, McFarland A, Harvey K, Naylor MJ, Lakhani SR, Simpson PT, Raghavendra A, Saunus J, Madore J, Kaplan W, Ormandy C, Millar EK, O'Toole S, Yun K, Swarbrick A. Junankar S, et al. Among authors: yang j. Nat Commun. 2015 Mar 27;6:6548. doi: 10.1038/ncomms7548. Nat Commun. 2015. PMID: 25813983 Free article.
Targeting stromal remodeling and cancer stem cell plasticity overcomes chemoresistance in triple negative breast cancer.
Cazet AS, Hui MN, Elsworth BL, Wu SZ, Roden D, Chan CL, Skhinas JN, Collot R, Yang J, Harvey K, Johan MZ, Cooper C, Nair R, Herrmann D, McFarland A, Deng N, Ruiz-Borrego M, Rojo F, Trigo JM, Bezares S, Caballero R, Lim E, Timpson P, O'Toole S, Watkins DN, Cox TR, Samuel MS, Martín M, Swarbrick A. Cazet AS, et al. Among authors: yang j. Nat Commun. 2018 Jul 24;9(1):2897. doi: 10.1038/s41467-018-05220-6. Nat Commun. 2018. PMID: 30042390 Free PMC article. Clinical Trial.
Id Proteins Promote a Cancer Stem Cell Phenotype in Mouse Models of Triple Negative Breast Cancer via Negative Regulation of Robo1.
Teo WS, Holliday H, Karthikeyan N, Cazet AS, Roden DL, Harvey K, Konrad CV, Murali R, Varghese BA, Thankamony AP, Chan CL, McFarland A, Junankar S, Ye S, Yang J, Nikolic I, Shah JS, Baker LA, Millar EKA, Naylor MJ, Ormandy CJ, Lakhani SR, Kaplan W, Mellick AS, O'Toole SA, Swarbrick A, Nair R. Teo WS, et al. Among authors: yang j. Front Cell Dev Biol. 2020 Jul 17;8:552. doi: 10.3389/fcell.2020.00552. eCollection 2020. Front Cell Dev Biol. 2020. PMID: 32766238 Free PMC article.
Targeting the Id1-Kif11 Axis in Triple-Negative Breast Cancer Using Combination Therapy.
Thankamony AP, Murali R, Karthikeyan N, Varghese BA, Teo WS, McFarland A, Roden DL, Holliday H, Konrad CV, Cazet A, Dodson E, Yang J, Baker LA, George JT, Levine H, Jolly MK, Swarbrick A, Nair R. Thankamony AP, et al. Among authors: yang j. Biomolecules. 2020 Sep 8;10(9):1295. doi: 10.3390/biom10091295. Biomolecules. 2020. PMID: 32911668 Free PMC article.
Temporally resolved proteomics identifies nidogen-2 as a cotarget in pancreatic cancer that modulates fibrosis and therapy response.
Pereira BA, Ritchie S, Chambers CR, Gordon KA, Magenau A, Murphy KJ, Nobis M, Tyma VM, Liew YF, Lucas MC, Naeini MM, Barkauskas DS, Chacon-Fajardo D, Howell AE, Parker AL, Warren SC, Reed DA, Lee V, Metcalf XL, Lee YK, O'Regan LP, Zhu J, Trpceski M, Fontaine ARM, Stoehr J, Rouet R, Lin X, Chitty JL, Porazinski S, Wu SZ, Filipe EC, Cadell AL, Holliday H, Yang J, Papanicolaou M, Lyons RJ, Zaratzian A, Tayao M, Da Silva A, Vennin C, Yin J, Dew AB, McMillan PJ, Goldstein LD, Deveson IW, Croucher DR, Samuel MS, Sim HW, Batten M, Chantrill L, Grimmond SM, Gill AJ, Samra J, Jeffry Evans TR, Sasaki T, Phan TG, Swarbrick A, Sansom OJ, Morton JP; Australian Pancreatic Cancer Matrix Atlas (APMA); Australian Pancreatic Cancer Genome Initiative (APGI); Pajic M, Parker BL, Herrmann D, Cox TR, Timpson P. Pereira BA, et al. Among authors: yang j. Sci Adv. 2024 Jul 5;10(27):eadl1197. doi: 10.1126/sciadv.adl1197. Epub 2024 Jul 3. Sci Adv. 2024. PMID: 38959305 Free PMC article.
MicroRNA profiling of the pubertal mouse mammary gland identifies miR-184 as a candidate breast tumour suppressor gene.
Phua YW, Nguyen A, Roden DL, Elsworth B, Deng N, Nikolic I, Yang J, Mcfarland A, Russell R, Kaplan W, Cowley MJ, Nair R, Zotenko E, O'Toole S, Tan SX, James DE, Clark SJ, Kouros-Mehr H, Swarbrick A. Phua YW, et al. Among authors: yang j. Breast Cancer Res. 2015 Jun 13;17(1):83. doi: 10.1186/s13058-015-0593-0. Breast Cancer Res. 2015. PMID: 26070602 Free PMC article.
Evaluation of FGFR targeting in breast cancer through interrogation of patient-derived models.
Chew NJ, Lim Kam Sian TCC, Nguyen EV, Shin SY, Yang J, Hui MN, Deng N, McLean CA, Welm AL, Lim E, Gregory P, Nottle T, Lang T, Vereker M, Richardson G, Kerr G, Micati D, Jardé T, Abud HE, Lee RS, Swarbrick A, Daly RJ. Chew NJ, et al. Among authors: yang j. Breast Cancer Res. 2021 Aug 3;23(1):82. doi: 10.1186/s13058-021-01461-4. Breast Cancer Res. 2021. PMID: 34344433 Free PMC article.
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