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Statin-mediated reduction in mitochondrial cholesterol primes an anti-inflammatory response in macrophages by upregulating Jmjd3.
Salloum Z, Dauner K, Li YF, Verma N, Valdivieso-González D, Almendro-Vedia V, Zhang JD, Nakka K, Chen MX, McDonald J, Corley CD, Sorisky A, Song BL, López-Montero I, Luo J, Dilworth JF, Zha X. Salloum Z, et al. Among authors: chen mx. Elife. 2024 Apr 11;13:e85964. doi: 10.7554/eLife.85964. Elife. 2024. PMID: 38602170 Free PMC article.
The palmitoylation of gasdermin D directs its membrane translocation and pore formation during pyroptosis.
Balasubramanian A, Hsu AY, Ghimire L, Tahir M, Devant P, Fontana P, Du G, Liu X, Fabin D, Kambara H, Xie X, Liu F, Hasegawa T, Xu R, Yu H, Chen M, Kolakowski S, Trauger S, Larsen MR, Wei W, Wu H, Kagan JC, Lieberman J, Luo HR. Balasubramanian A, et al. Sci Immunol. 2024 Apr 12;9(94):eadn1452. doi: 10.1126/sciimmunol.adn1452. Epub 2024 Apr 12. Sci Immunol. 2024. PMID: 38530158
466 results