Prabhu N - Search Results

1

Identification of an inhibitory pocket in falcilysin provides a new avenue for malaria drug development.

Wirjanata G, Lin J, Dziekan JM, El Sahili A, Chung Z, Tjia S, Binte Zulkifli NE, Boentoro J, Tham R, Jia LS, Go KD, Yu H, Partridge A, Olsen D, Prabhu N, Sobota RM, Nordlund P, Lescar J, Bozdech Z. Wirjanata G, et al. Among authors: prabhu n. Cell Chem Biol. 2024 Apr 18;31(4):743-759.e8. doi: 10.1016/j.chembiol.2024.03.002. Epub 2024 Apr 8. Cell Chem Biol. 2024. PMID: 38593807

2

Dual blockade of the lipid kinase PIP4Ks and mitotic pathways leads to cancer-selective lethality.

Kitagawa M, Liao PJ, Lee KH, Wong J, Shang SC, Minami N, Sampetrean O, Saya H, Lingyun D, Prabhu N, Diam GK, Sobota R, Larsson A, Nordlund P, McCormick F, Ghosh S, Epstein DM, Dymock BW, Lee SH. Kitagawa M, et al. Among authors: prabhu n. Nat Commun. 2017 Dec 19;8(1):2200. doi: 10.1038/s41467-017-02287-5. Nat Commun. 2017. PMID: 29259156 Free PMC article.

3

Thermal proximity coaggregation for system-wide profiling of protein complex dynamics in cells.

Tan CSH, Go KD, Bisteau X, Dai L, Yong CH, Prabhu N, Ozturk MB, Lim YT, Sreekumar L, Lengqvist J, Tergaonkar V, Kaldis P, Sobota RM, Nordlund P. Tan CSH, et al. Among authors: prabhu n. Science. 2018 Mar 9;359(6380):1170-1177. doi: 10.1126/science.aan0346. Epub 2018 Feb 8. Science. 2018. PMID: 29439025

4

Modulation of Protein-Interaction States through the Cell Cycle.

Dai L, Zhao T, Bisteau X, Sun W, Prabhu N, Lim YT, Sobota RM, Kaldis P, Nordlund P. Dai L, et al. Among authors: prabhu n. Cell. 2018 May 31;173(6):1481-1494.e13. doi: 10.1016/j.cell.2018.03.065. Epub 2018 Apr 26. Cell. 2018. PMID: 29706543 Free article.

5

An efficient proteome-wide strategy for discovery and characterization of cellular nucleotide-protein interactions.

Lim YT, Prabhu N, Dai L, Go KD, Chen D, Sreekumar L, Egeblad L, Eriksson S, Chen L, Veerappan S, Teo HL, Tan CSH, Lengqvist J, Larsson A, Sobota RM, Nordlund P. Lim YT, et al. Among authors: prabhu n. PLoS One. 2018 Dec 6;13(12):e0208273. doi: 10.1371/journal.pone.0208273. eCollection 2018. PLoS One. 2018. PMID: 30521565 Free PMC article.

6

Identifying purine nucleoside phosphorylase as the target of quinine using cellular thermal shift assay.

Dziekan JM, Yu H, Chen D, Dai L, Wirjanata G, Larsson A, Prabhu N, Sobota RM, Bozdech Z, Nordlund P. Dziekan JM, et al. Among authors: prabhu n. Sci Transl Med. 2019 Jan 2;11(473):eaau3174. doi: 10.1126/scitranslmed.aau3174. Sci Transl Med. 2019. PMID: 30602534

7

Monitoring structural modulation of redox-sensitive proteins in cells with MS-CETSA.

Sun W, Dai L, Yu H, Puspita B, Zhao T, Li F, Tan JL, Lim YT, Chen MW, Sobota RM, Tenen DG, Prabhu N, Nordlund P. Sun W, et al. Among authors: prabhu n. Redox Biol. 2019 Jun;24:101168. doi: 10.1016/j.redox.2019.101168. Epub 2019 Mar 14. Redox Biol. 2019. PMID: 30925293 Free PMC article.

8

Horizontal Cell Biology: Monitoring Global Changes of Protein Interaction States with the Proteome-Wide Cellular Thermal Shift Assay (CETSA).

Dai L, Prabhu N, Yu LY, Bacanu S, Ramos AD, Nordlund P. Dai L, et al. Among authors: prabhu n. Annu Rev Biochem. 2019 Jun 20;88:383-408. doi: 10.1146/annurev-biochem-062917-012837. Epub 2019 Apr 2. Annu Rev Biochem. 2019. PMID: 30939043 Review.

9

CETSA in integrated proteomics studies of cellular processes.

Prabhu N, Dai L, Nordlund P. Prabhu N, et al. Curr Opin Chem Biol. 2020 Feb;54:54-62. doi: 10.1016/j.cbpa.2019.11.004. Epub 2019 Dec 12. Curr Opin Chem Biol. 2020. PMID: 31838273 Review.

10

Cellular thermal shift assay for the identification of drug-target interactions in the Plasmodium falciparum proteome.

Dziekan JM, Wirjanata G, Dai L, Go KD, Yu H, Lim YT, Chen L, Wang LC, Puspita B, Prabhu N, Sobota RM, Nordlund P, Bozdech Z. Dziekan JM, et al. Among authors: prabhu n. Nat Protoc. 2020 Jun;15(6):1881-1921. doi: 10.1038/s41596-020-0310-z. Epub 2020 Apr 27. Nat Protoc. 2020. PMID: 32341577

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