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Androgen loss weakens anti-tumor immunity and accelerates brain tumor growth.
Lee J, Chung YM, Curtin L, Silver DJ, Hao Y, Li C, Volovetz J, Hong ES, Jarmula J, Wang SZ, Kay KE, Berens M, Nicosia M, Swanson KR, Sharifi N, Lathia JD. Lee J, et al. Among authors: berens m. Res Sq [Preprint]. 2024 Mar 29:rs.3.rs-4014556. doi: 10.21203/rs.3.rs-4014556/v1. Res Sq. 2024. PMID: 38585839 Free PMC article. Preprint.
JAM-A functions as a female microglial tumor suppressor in glioblastoma.
Turaga SM, Silver DJ, Bayik D, Paouri E, Peng S, Lauko A, Alban TJ, Borjini N, Stanko S, Naik UP, Keri RA, Connor JR, Barnholtz-Sloan JS, Rubin JB, Berens M, Davalos D, Lathia JD. Turaga SM, et al. Among authors: berens m. Neuro Oncol. 2020 Nov 26;22(11):1591-1601. doi: 10.1093/neuonc/noaa148. Neuro Oncol. 2020. PMID: 32592484 Free PMC article.
Evaluating the Base Excision Repair Inhibitor TRC102 and Temozolomide for Patients with Recurrent Glioblastoma in the Phase 2 Adult Brain Tumor Consortium Trial BERT.
Ahluwalia MS, Ozair A, Drappatz J, Ye X, Peng S, Lee M, Rath S, Dhruv H, Hao Y, Berens ME, Walbert T, Holdhoff M, Lesser GJ, Cloughesy TF, Sloan AE, Takebe N, Couce M, Peereboom DM, Nabors B, Wen PY, Grossman SA, Rogers LR. Ahluwalia MS, et al. Among authors: berens me. Clin Cancer Res. 2024 Aug 1;30(15):3167-3178. doi: 10.1158/1078-0432.CCR-23-4098. Clin Cancer Res. 2024. PMID: 38836759 Clinical Trial.
Glioblastoma vulnerability to neddylation inhibition is dependent on PTEN status, and dysregulation of the cell cycle and DNA replication.
Taylor B, Tang N, Hao Y, Lee M, Peng S, Bybee R, Hartman L, Garcia-Mansfield K, Sharma R, Pirrotte P, Ma J, Parisian AD, Furnari F, Dhruv HD, Berens ME. Taylor B, et al. Among authors: berens me. Neurooncol Adv. 2024 Jun 20;6(1):vdae104. doi: 10.1093/noajnl/vdae104. eCollection 2024 Jan-Dec. Neurooncol Adv. 2024. PMID: 39119276 Free PMC article.
Females have the survival advantage in glioblastoma.
Ostrom QT, Rubin JB, Lathia JD, Berens ME, Barnholtz-Sloan JS. Ostrom QT, et al. Neuro Oncol. 2018 Mar 27;20(4):576-577. doi: 10.1093/neuonc/noy002. Neuro Oncol. 2018. PMID: 29474647 Free PMC article. No abstract available.
Sex Differences in Cancer Incidence and Survival: A Pan-Cancer Analysis.
Dong M, Cioffi G, Wang J, Waite KA, Ostrom QT, Kruchko C, Lathia JD, Rubin JB, Berens ME, Connor J, Barnholtz-Sloan JS. Dong M, et al. Among authors: berens me. Cancer Epidemiol Biomarkers Prev. 2020 Jul;29(7):1389-1397. doi: 10.1158/1055-9965.EPI-20-0036. Epub 2020 Apr 29. Cancer Epidemiol Biomarkers Prev. 2020. PMID: 32349967
223 results