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Low TGF-β1 plasma levels are associated with cognitive decline in Down syndrome.
Grasso M, Fidilio A, L'Episcopo F, Recupero M, Barone C, Bacalini MG, Benatti C, Giambirtone MC, Caruso G, Greco D, Di Nuovo S, Romano C, Ferri R, Buono S, Cuello AC, Blom JMC, Tascedda F, Piazza PV, De La Torre R, Caraci F. Grasso M, et al. Among authors: piazza pv. Front Pharmacol. 2024 Mar 21;15:1379965. doi: 10.3389/fphar.2024.1379965. eCollection 2024. Front Pharmacol. 2024. PMID: 38576478 Free PMC article.
Signaling-specific inhibition of the CB1 receptor for cannabis use disorder: phase 1 and phase 2a randomized trials.
Haney M, Vallée M, Fabre S, Collins Reed S, Zanese M, Campistron G, Arout CA, Foltin RW, Cooper ZD, Kearney-Ramos T, Metna M, Justinova Z, Schindler C, Hebert-Chatelain E, Bellocchio L, Cathala A, Bari A, Serrat R, Finlay DB, Caraci F, Redon B, Martín-García E, Busquets-Garcia A, Matias I, Levin FR, Felpin FX, Simon N, Cota D, Spampinato U, Maldonado R, Shaham Y, Glass M, Thomsen LL, Mengel H, Marsicano G, Monlezun S, Revest JM, Piazza PV. Haney M, et al. Among authors: piazza pv. Nat Med. 2023 Jun;29(6):1487-1499. doi: 10.1038/s41591-023-02381-w. Epub 2023 Jun 8. Nat Med. 2023. PMID: 37291212 Free PMC article. Clinical Trial.
Differential expression of the neuronal CB1 cannabinoid receptor in the hippocampus of male Ts65Dn Down syndrome mouse model.
Di Franco N, Drutel G, Roullot-Lacarrière V, Julio-Kalajzic F, Lalanne V, Grel A, Leste-Lasserre T, Matias I, Cannich A, Gonzales D, Simon V, Cota D, Marsicano G, Piazza PV, Vallée M, Revest JM. Di Franco N, et al. Among authors: piazza pv. Mol Cell Neurosci. 2022 Mar;119:103705. doi: 10.1016/j.mcn.2022.103705. Epub 2022 Feb 11. Mol Cell Neurosci. 2022. PMID: 35158060 Free article.
Glucose metabolism links astroglial mitochondria to cannabinoid effects.
Jimenez-Blasco D, Busquets-Garcia A, Hebert-Chatelain E, Serrat R, Vicente-Gutierrez C, Ioannidou C, Gómez-Sotres P, Lopez-Fabuel I, Resch-Beusher M, Resel E, Arnouil D, Saraswat D, Varilh M, Cannich A, Julio-Kalajzic F, Bonilla-Del Río I, Almeida A, Puente N, Achicallende S, Lopez-Rodriguez ML, Jollé C, Déglon N, Pellerin L, Josephine C, Bonvento G, Panatier A, Lutz B, Piazza PV, Guzmán M, Bellocchio L, Bouzier-Sore AK, Grandes P, Bolaños JP, Marsicano G. Jimenez-Blasco D, et al. Among authors: piazza pv. Nature. 2020 Jul;583(7817):603-608. doi: 10.1038/s41586-020-2470-y. Epub 2020 Jul 8. Nature. 2020. PMID: 32641832
Cannabinoid type-1 receptor blockade restores neurological phenotypes in two models for Down syndrome.
Navarro-Romero A, Vázquez-Oliver A, Gomis-González M, Garzón-Montesinos C, Falcón-Moya R, Pastor A, Martín-García E, Pizarro N, Busquets-Garcia A, Revest JM, Piazza PV, Bosch F, Dierssen M, de la Torre R, Rodríguez-Moreno A, Maldonado R, Ozaita A. Navarro-Romero A, et al. Among authors: piazza pv. Neurobiol Dis. 2019 May;125:92-106. doi: 10.1016/j.nbd.2019.01.014. Epub 2019 Jan 25. Neurobiol Dis. 2019. PMID: 30685352
179 results