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106 results

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LOAd703, an oncolytic virus-based immunostimulatory gene therapy, combined with chemotherapy for unresectable or metastatic pancreatic cancer (LOKON001): results from arm 1 of a non-randomised, single-centre, phase 1/2 study.
Musher BL, Rowinsky EK, Smaglo BG, Abidi W, Othman M, Patel K, Jawaid S, Jing J, Brisco A, Leen AM, Wu M, Sandin LC, Wenthe J, Eriksson E, Ullenhag GJ, Grilley B, Leja-Jarblad J, Hilsenbeck SG, Brenner MK, Loskog ASI. Musher BL, et al. Among authors: leen am. Lancet Oncol. 2024 Apr;25(4):488-500. doi: 10.1016/S1470-2045(24)00079-2. Lancet Oncol. 2024. PMID: 38547893 Clinical Trial.
Targeting IDH2R140Q and other neoantigens in acute myeloid leukemia.
Leung WK, Torres Chavez AG, French-Kim M, Shafer P, Mamonkin M, Hill LC, Kuvalekar M, Velazquez Y, Watanabe A, Watanabe N, Hoyos V, Lulla P, Leen AM. Leung WK, et al. Among authors: leen am. Blood. 2024 Apr 25;143(17):1726-1737. doi: 10.1182/blood.2023021979. Blood. 2024. PMID: 38241630
Therapy With Allogeneic Severe Acute Respiratory Syndrome Coronavirus-2-Specific T Cells for Persistent Coronavirus Disease 2019 in Immunocompromised Patients.
Haidar G, Jacobs JL, Kramer KH, Naqvi A, Heaps A, Parikh U, McCormick KD, Sobolewski MD, Agha M, Bogdanovich T, Bushunow V, Farah R, Hensley M, Hsu YS, Johnson B, Klamar-Blain C, Kozar J, Lendermon E, Macatangay BJC, Marino CC, Raptis A, Salese E, Silveira FP, Leen AM, Marshall WL, Miller M, Patel B, Atillasoy E, Mellors JW. Haidar G, et al. Among authors: leen am. Clin Infect Dis. 2023 Sep 11;77(5):696-702. doi: 10.1093/cid/ciad233. Clin Infect Dis. 2023. PMID: 37078720 Free PMC article.
A dual-luciferase bioluminescence system for the assessment of cellular therapies.
Torres Chavez AG, McKenna MK, Balasubramanian K, Riffle L, Patel NL, Kalen JD, St Croix B, Leen AM, Bajgain P. Torres Chavez AG, et al. Among authors: leen am. Mol Ther Oncol. 2024 Jan 10;32(1):200763. doi: 10.1016/j.omton.2024.200763. eCollection 2024 Mar 21. Mol Ther Oncol. 2024. PMID: 38596291 Free PMC article.
Incongruity between T cell receptor recognition of breast cancer hotspot mutations ESR1 Y537S and D538G following exogenous peptide loading versus endogenous antigen processing.
Shafer P, Leung WK, Woods M, Choi JM, Rodriguez-Plata CM, Maknojia A, Mosquera A, Somes LK, Joubert J, Manliguez A, Ranjan R, Burt B, Lee HS, Zhang B, Fuqua S, Rooney C, Leen AM, Hoyos V. Shafer P, et al. Among authors: leen am. Cytotherapy. 2024 Mar;26(3):266-275. doi: 10.1016/j.jcyt.2023.12.002. Epub 2024 Jan 15. Cytotherapy. 2024. PMID: 38231165 Free article.
Posoleucel, an Allogeneic, Off-the-Shelf Multivirus-Specific T-Cell Therapy, for the Treatment of Refractory Viral Infections in the Post-HCT Setting.
Pfeiffer T, Tzannou I, Wu M, Ramos C, Sasa G, Martinez C, Lulla P, Krance RA, Scherer L, Ruderfer D, Naik S, Bocchini C, Fraser IP, Patel B, Ward D, Wang T, Heslop HE, Leen AM, Omer B. Pfeiffer T, et al. Among authors: leen am. Clin Cancer Res. 2023 Jan 17;29(2):324-330. doi: 10.1158/1078-0432.CCR-22-2415. Clin Cancer Res. 2023. PMID: 36628536 Free PMC article. Clinical Trial.
106 results