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Purine nucleotide depletion prompts cell migration by stimulating the serine synthesis pathway.
Soflaee MH, Kesavan R, Sahu U, Tasdogan A, Villa E, Djabari Z, Cai F, Tran DH, Vu HS, Ali ES, Rion H, O'Hara BP, Kelekar S, Hallett JH, Martin M, Mathews TP, Gao P, Asara JM, Manning BD, Ben-Sahra I, Hoxhaj G. Soflaee MH, et al. Among authors: o hara bp. Nat Commun. 2022 May 16;13(1):2698. doi: 10.1038/s41467-022-30362-z. Nat Commun. 2022. PMID: 35577785 Free PMC article.
C16orf72/HAPSTR1 is a molecular rheostat in an integrated network of stress response pathways.
Amici DR, Ansel DJ, Metz KA, Smith RS, Phoumyvong CM, Gayatri S, Chamera T, Edwards SL, O'Hara BP, Srivastava S, Brockway S, Takagishi SR, Cho BK, Goo YA, Kelleher NL, Ben-Sahra I, Foltz DR, Li J, Mendillo ML. Amici DR, et al. Among authors: o hara bp. Proc Natl Acad Sci U S A. 2022 Jul 5;119(27):e2111262119. doi: 10.1073/pnas.2111262119. Epub 2022 Jul 1. Proc Natl Acad Sci U S A. 2022. PMID: 35776542 Free PMC article.
Dual Covalent Inhibition of PKM and IMPDH Targets Metabolism in Cutaneous Metastatic Melanoma.
Zerhouni M, Martin AR, Furstoss N, Gutierrez VS, Jaune E, Tekaya N, Beranger GE, Abbe P, Regazzetti C, Amdouni H, Driowya M, Dubreuil P, Luciano F, Jacquel A, Tulic MK, Cluzeau T, O'Hara BP, Ben-Sahra I, Passeron T, Benhida R, Robert G, Auberger P, Rocchi S. Zerhouni M, et al. Among authors: o hara bp. Cancer Res. 2021 Jul 15;81(14):3806-3821. doi: 10.1158/0008-5472.CAN-20-2114. Epub 2021 Jun 7. Cancer Res. 2021. PMID: 34099492
Mechano-dependent sorbitol accumulation supports biomolecular condensate.
Torrino S, Oldham WM, Tejedor AR, Burgos IS, Rachedi N, Fraissard K, Chauvet C, Sbai C, O'Hara BP, Abélanet S, Brau F, Clavel S, Collepardo-Guevara R, Espinosa JR, Ben-Sahra I, Bertero T. Torrino S, et al. Among authors: o hara bp. bioRxiv [Preprint]. 2023 Jul 25:2023.07.24.550444. doi: 10.1101/2023.07.24.550444. bioRxiv. 2023. PMID: 37546967 Free PMC article. Preprint.
ETV7 is an essential component of a rapamycin-insensitive mTOR complex in cancer.
Harwood FC, Klein Geltink RI, O'Hara BP, Cardone M, Janke L, Finkelstein D, Entin I, Paul L, Houghton PJ, Grosveld GC. Harwood FC, et al. Among authors: o hara bp. Sci Adv. 2018 Sep 12;4(9):eaar3938. doi: 10.1126/sciadv.aar3938. eCollection 2018 Sep. Sci Adv. 2018. PMID: 30258985 Free PMC article.
23 results