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Inhibition of MALT1 and BCL2 Induces Synergistic Antitumor Activity in Models of B-Cell Lymphoma.
Plotnik JP, Richardson AE, Yang H, Rojas E, Bontcheva V, Dowell C, Parsons S, Wilson A, Ravanmehr V, Will C, Jung P, Zhu H, Partha SK, Panchal SC, Mali RS, Kohlhapp FJ, McClure RA, Ramathal CY, George MD, Jhala M, Elsen NL, Qiu W, Judge RA, Pan C, Mastracchio A, Henderson J, Meulbroek JA, Green MR, Pappano WN. Plotnik JP, et al. Among authors: kohlhapp fj. Mol Cancer Ther. 2024 Jul 2;23(7):949-960. doi: 10.1158/1535-7163.MCT-23-0518. Mol Cancer Ther. 2024. PMID: 38507740 Free PMC article.
Venetoclax Increases Intratumoral Effector T Cells and Antitumor Efficacy in Combination with Immune Checkpoint Blockade.
Kohlhapp FJ, Haribhai D, Mathew R, Duggan R, Ellis PA, Wang R, Lasater EA, Shi Y, Dave N, Riehm JJ, Robinson VA, Do AD, Li Y, Orr CJ, Sampath D, Raval A, Merchant M, Bhathena A, Salem AH, Hamel KM, Leverson JD, Donawho C, Pappano WN, Uziel T. Kohlhapp FJ, et al. Cancer Discov. 2021 Jan;11(1):68-79. doi: 10.1158/2159-8290.CD-19-0759. Epub 2020 Sep 4. Cancer Discov. 2021. PMID: 32887697
Intratumoral injection of the seasonal flu shot converts immunologically cold tumors to hot and serves as an immunotherapy for cancer.
Newman JH, Chesson CB, Herzog NL, Bommareddy PK, Aspromonte SM, Pepe R, Estupinian R, Aboelatta MM, Buddhadev S, Tarabichi S, Lee M, Li S, Medina DJ, Giurini EF, Gupta KH, Guevara-Aleman G, Rossi M, Nowicki C, Abed A, Goldufsky JW, Broucek JR, Redondo RE, Rotter D, Jhawar SR, Wang SJ, Kohlhapp FJ, Kaufman HL, Thomas PG, Gupta V, Kuzel TM, Reiser J, Paras J, Kane MP, Singer EA, Malhotra J, Denzin LK, Sant'Angelo DB, Rabson AB, Lee LY, Lasfar A, Langenfeld J, Schenkel JM, Fidler MJ, Ruiz ES, Marzo AL, Rudra JS, Silk AW, Zloza A. Newman JH, et al. Among authors: kohlhapp fj. Proc Natl Acad Sci U S A. 2020 Jan 14;117(2):1119-1128. doi: 10.1073/pnas.1904022116. Epub 2019 Dec 30. Proc Natl Acad Sci U S A. 2020. PMID: 31888983 Free PMC article.
Oncolytic Viruses-Natural and Genetically Engineered Cancer Immunotherapies.
Jhawar SR, Thandoni A, Bommareddy PK, Hassan S, Kohlhapp FJ, Goyal S, Schenkel JM, Silk AW, Zloza A. Jhawar SR, et al. Among authors: kohlhapp fj. Front Oncol. 2017 Sep 11;7:202. doi: 10.3389/fonc.2017.00202. eCollection 2017. Front Oncol. 2017. PMID: 28955655 Free PMC article. Review.
Non-oncogenic Acute Viral Infections Disrupt Anti-cancer Responses and Lead to Accelerated Cancer-Specific Host Death.
Kohlhapp FJ, Huelsmann EJ, Lacek AT, Schenkel JM, Lusciks J, Broucek JR, Goldufsky JW, Hughes T, Zayas JP, Dolubizno H, Sowell RT, Kühner R, Burd S, Kubasiak JC, Nabatiyan A, Marshall S, Bommareddy PK, Li S, Newman JH, Monken CE, Shafikhani SH, Marzo AL, Guevara-Patino JA, Lasfar A, Thomas PG, Lattime EC, Kaufman HL, Zloza A. Kohlhapp FJ, et al. Cell Rep. 2016 Oct 18;17(4):957-965. doi: 10.1016/j.celrep.2016.09.068. Cell Rep. 2016. PMID: 27760326 Free PMC article.
Oncolytic viruses: a new class of immunotherapy drugs.
Kaufman HL, Kohlhapp FJ, Zloza A. Kaufman HL, et al. Among authors: kohlhapp fj. Nat Rev Drug Discov. 2016 Aug 30;15(9):660. doi: 10.1038/nrd.2016.178. Nat Rev Drug Discov. 2016. PMID: 30907381 Free PMC article.
25 results