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Multiomic profiling of human clonal hematopoiesis reveals genotype and cell-specific inflammatory pathway activation.
Heimlich JB, Bhat P, Parker AC, Jenkins MT, Vlasschaert C, Ulloa J, Van Amburg JC, Potts CR, Olson S, Silver AJ, Ahmad A, Sharber B, Brown D, Hu N, van Galen P, Savona MR, Bick AG, Ferrell PB. Heimlich JB, et al. Among authors: silver aj. Blood Adv. 2024 Jul 23;8(14):3665-3678. doi: 10.1182/bloodadvances.2023011445. Blood Adv. 2024. PMID: 38507736 Free PMC article.
Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease.
Jaiswal S, Natarajan P, Silver AJ, Gibson CJ, Bick AG, Shvartz E, McConkey M, Gupta N, Gabriel S, Ardissino D, Baber U, Mehran R, Fuster V, Danesh J, Frossard P, Saleheen D, Melander O, Sukhova GK, Neuberg D, Libby P, Kathiresan S, Ebert BL. Jaiswal S, et al. Among authors: silver aj. N Engl J Med. 2017 Jul 13;377(2):111-121. doi: 10.1056/NEJMoa1701719. Epub 2017 Jun 21. N Engl J Med. 2017. PMID: 28636844 Free PMC article.
Clonal hematopoiesis: Pre-cancer PLUS.
Silver AJ, Jaiswal S. Silver AJ, et al. Adv Cancer Res. 2019;141:85-128. doi: 10.1016/bs.acr.2018.12.003. Epub 2019 Jan 14. Adv Cancer Res. 2019. PMID: 30691686 Review.
Germline risk of clonal haematopoiesis.
Silver AJ, Bick AG, Savona MR. Silver AJ, et al. Nat Rev Genet. 2021 Sep;22(9):603-617. doi: 10.1038/s41576-021-00356-6. Epub 2021 May 13. Nat Rev Genet. 2021. PMID: 33986496 Free PMC article. Review.
High burden of clonal hematopoiesis in first responders exposed to the World Trade Center disaster.
Jasra S, Giricz O, Zeig-Owens R, Pradhan K, Goldfarb DG, Barreto-Galvez A, Silver AJ, Chen J, Sahu S, Gordon-Mitchell S, Choudhary GS, Aluri S, Bhagat TD, Shastri A, Bejan CA, Stockton SS, Spaulding TP, Thiruthuvanathan V, Goto H, Gerhardt J, Haider SH, Veerappan A, Bartenstein M, Nwankwo G, Landgren O, Weiden MD, Lekostaj J, Bender R, Fletcher F, Greenberger L, Ebert BL, Steidl U, Will B, Nolan A, Madireddy A, Savona MR, Prezant DJ, Verma A. Jasra S, et al. Among authors: silver aj. Nat Med. 2022 Mar;28(3):468-471. doi: 10.1038/s41591-022-01708-3. Epub 2022 Mar 7. Nat Med. 2022. PMID: 35256801 Free PMC article.
Patient-specific comorbidities as prognostic variables for survival in myelofibrosis.
Sochacki AL, Bejan CA, Zhao S, Patel A, Kishtagari A, Spaulding TP, Silver AJ, Stockton SS, Pugh K, Dorand RD, Bhatta M, Strayer N, Zhang S, Snider CA, Stricker T, Nazha A, Bick AG, Xu Y, Savona MR. Sochacki AL, et al. Among authors: silver aj. Blood Adv. 2023 Mar 14;7(5):756-767. doi: 10.1182/bloodadvances.2021006318. Blood Adv. 2023. PMID: 35420683 Free PMC article.
Cost-effective and scalable clonal hematopoiesis assay provides insight into clonal dynamics.
Mack T, Vlasschaert C, von Beck K, Silver AJ, Heimlich JB, Poisner H, Condon HR, Ulloa J, Sochacki AL, Spaulding TP, Kishtagari A, Bejan CA, Xu Y, Savona MR, Jones A, Bick A. Mack T, et al. Among authors: silver aj. medRxiv [Preprint]. 2023 Nov 9:2023.11.08.23298270. doi: 10.1101/2023.11.08.23298270. medRxiv. 2023. Update in: J Mol Diagn. 2024 Jul;26(7):563-573. doi: 10.1016/j.jmoldx.2024.03.007. PMID: 37986782 Free PMC article. Updated. Preprint.
Driver mutation zygosity is a critical factor in predicting clonal hematopoiesis transformation risk.
Kishtagari A, Khan MAW, Li Y, Vlasschaert C, Marneni N, Silver AJ, von Beck K, Spaulding T, Stockton S, Snider C, Sochacki A, Dorand D, Mack TM, Ferrell PB Jr, Xu Y, Bejan CA, Savona MR, Bick AG. Kishtagari A, et al. Among authors: silver aj. Blood Cancer J. 2024 Jan 15;14(1):6. doi: 10.1038/s41408-023-00974-9. Blood Cancer J. 2024. PMID: 38225345 Free PMC article.
87 results