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Page 1
Imaging and Molecular Annotation of Xenographs and Tumours (IMAXT): High throughput data and analysis infrastructure.
González-Solares EA, Dariush A, González-Fernández C, Küpcü Yoldaş A, Molaeinezhad A, Al Sa'd M, Smith L, Whitmarsh T, Millar N, Chornay N, Falciatori I, Fatemi A, Goodwin D, Kuett L, Mulvey CM, Páez Ribes M, Qosaj F, Roth A, Vázquez-García I, Watson SS, Windhager J, Aparicio S, Bodenmiller B, Boyden E, Caldas C, Harris O, Shah SP, Tavaré S; CRUK IMAXT Grand Challenge Team; Bressan D, Hannon GJ, Walton NA. González-Solares EA, et al. Among authors: bressan d. Biol Imaging. 2023 Apr 14;3:e11. doi: 10.1017/S2633903X23000090. eCollection 2023. Biol Imaging. 2023. PMID: 38487685 Free PMC article.
Clonal Decomposition and DNA Replication States Defined by Scaled Single-Cell Genome Sequencing.
Laks E, McPherson A, Zahn H, Lai D, Steif A, Brimhall J, Biele J, Wang B, Masud T, Ting J, Grewal D, Nielsen C, Leung S, Bojilova V, Smith M, Golovko O, Poon S, Eirew P, Kabeer F, Ruiz de Algara T, Lee SR, Taghiyar MJ, Huebner C, Ngo J, Chan T, Vatrt-Watts S, Walters P, Abrar N, Chan S, Wiens M, Martin L, Scott RW, Underhill TM, Chavez E, Steidl C, Da Costa D, Ma Y, Coope RJN, Corbett R, Pleasance S, Moore R, Mungall AJ, Mar C, Cafferty F, Gelmon K, Chia S; CRUK IMAXT Grand Challenge Team; Marra MA, Hansen C, Shah SP, Aparicio S. Laks E, et al. Cell. 2019 Nov 14;179(5):1207-1221.e22. doi: 10.1016/j.cell.2019.10.026. Cell. 2019. PMID: 31730858 Free PMC article.
Landscapes of cellular phenotypic diversity in breast cancer xenografts and their impact on drug response.
Georgopoulou D, Callari M, Rueda OM, Shea A, Martin A, Giovannetti A, Qosaj F, Dariush A, Chin SF, Carnevalli LS, Provenzano E, Greenwood W, Lerda G, Esmaeilishirazifard E, O'Reilly M, Serra V, Bressan D; IMAXT Consortium; Mills GB, Ali HR, Cosulich SS, Hannon GJ, Bruna A, Caldas C. Georgopoulou D, et al. Among authors: bressan d. Nat Commun. 2021 Mar 31;12(1):1998. doi: 10.1038/s41467-021-22303-z. Nat Commun. 2021. PMID: 33790302 Free PMC article.
Clonal fitness inferred from time-series modelling of single-cell cancer genomes.
Salehi S, Kabeer F, Ceglia N, Andronescu M, Williams MJ, Campbell KR, Masud T, Wang B, Biele J, Brimhall J, Gee D, Lee H, Ting J, Zhang AW, Tran H, O'Flanagan C, Dorri F, Rusk N, de Algara TR, Lee SR, Cheng BYC, Eirew P, Kono T, Pham J, Grewal D, Lai D, Moore R, Mungall AJ, Marra MA; IMAXT Consortium; McPherson A, Bouchard-Côté A, Aparicio S, Shah SP. Salehi S, et al. Nature. 2021 Jul;595(7868):585-590. doi: 10.1038/s41586-021-03648-3. Epub 2021 Jun 23. Nature. 2021. PMID: 34163070 Free PMC article.
Single-cell genomic variation induced by mutational processes in cancer.
Funnell T, O'Flanagan CH, Williams MJ, McPherson A, McKinney S, Kabeer F, Lee H, Salehi S, Vázquez-García I, Shi H, Leventhal E, Masud T, Eirew P, Yap D, Zhang AW, Lim JLP, Wang B, Brimhall J, Biele J, Ting J, Au V, Van Vliet M, Liu YF, Beatty S, Lai D, Pham J, Grewal D, Abrams D, Havasov E, Leung S, Bojilova V, Moore RA, Rusk N, Uhlitz F, Ceglia N, Weiner AC, Zaikova E, Douglas JM, Zamarin D, Weigelt B, Kim SH, Da Cruz Paula A, Reis-Filho JS, Martin SD, Li Y, Xu H, de Algara TR, Lee SR, Llanos VC, Huntsman DG, McAlpine JN; IMAXT Consortium; Shah SP, Aparicio S. Funnell T, et al. Nature. 2022 Dec;612(7938):106-115. doi: 10.1038/s41586-022-05249-0. Epub 2022 Oct 26. Nature. 2022. PMID: 36289342 Free PMC article.
The dawn of spatial omics.
Bressan D, Battistoni G, Hannon GJ. Bressan D, et al. Science. 2023 Aug 4;381(6657):eabq4964. doi: 10.1126/science.abq4964. Epub 2023 Aug 4. Science. 2023. PMID: 37535749 Free PMC article. Review.
FOXC2 promotes vasculogenic mimicry and resistance to anti-angiogenic therapy.
Cannell IG, Sawicka K, Pearsall I, Wild SA, Deighton L, Pearsall SM, Lerda G, Joud F, Khan S, Bruna A, Simpson KL, Mulvey CM, Nugent F, Qosaj F, Bressan D; CRUK IMAXT Grand Challenge Team; Dive C, Caldas C, Hannon GJ. Cannell IG, et al. Among authors: bressan d. Cell Rep. 2023 Aug 29;42(8):112791. doi: 10.1016/j.celrep.2023.112791. Epub 2023 Jul 26. Cell Rep. 2023. PMID: 37499655 Free article.
Dual-modality imaging of immunofluorescence and imaging mass cytometry for whole slide imaging with accurate single-cell segmentation.
Kim EN, Chen PZ, Bressan D, Tripathi M, Miremadi A, di Pietro M, Coussens LM, Hannon GJ, Fitzgerald RC, Zhuang L, Chang YH. Kim EN, et al. Among authors: bressan d. bioRxiv [Preprint]. 2023 Feb 23:2023.02.23.529718. doi: 10.1101/2023.02.23.529718. bioRxiv. 2023. Update in: Cell Rep Methods. 2023 Oct 23;3(10):100595. doi: 10.1016/j.crmeth.2023.100595. PMID: 36865274 Free PMC article. Updated. Preprint.
Genome wide screen of RNAi molecules against SARS-CoV-2 creates a broadly potent prophylaxis.
Yogev O, Weissbrod O, Battistoni G, Bressan D, Naamti A, Falciatori I, Berkyurek AC, Rasnic R, Hosmillo M, Ilan S, Grossman I, McCormick L, Honeycutt CC, Johnston T, Gagne M, Douek DC, Goodfellow I, Hannon GJ, Erlich Y. Yogev O, et al. Among authors: bressan d. bioRxiv [Preprint]. 2022 Apr 12:2022.04.12.488010. doi: 10.1101/2022.04.12.488010. bioRxiv. 2022. Update in: Commun Biol. 2023 Mar 16;6(1):277. doi: 10.1038/s42003-023-04589-5. PMID: 35441162 Free PMC article. Updated. Preprint.
43 results