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Hepatic malonyl-CoA synthesis restrains gluconeogenesis by suppressing fat oxidation, pyruvate carboxylation, and amino acid availability.
Deja S, Fletcher JA, Kim CW, Kucejova B, Fu X, Mizerska M, Villegas M, Pudelko-Malik N, Browder N, Inigo-Vollmer M, Menezes CJ, Mishra P, Berglund ED, Browning JD, Thyfault JP, Young JD, Horton JD, Burgess SC. Deja S, et al. Cell Metab. 2024 May 7;36(5):1088-1104.e12. doi: 10.1016/j.cmet.2024.02.004. Epub 2024 Mar 5. Cell Metab. 2024. PMID: 38447582 Free article.
Endogenous renal adiponectin drives gluconeogenesis through enhancing pyruvate and fatty acid utilization.
Onodera T, Wang MY, Rutkowski JM, Deja S, Chen S, Balzer MS, Kim DS, Sun X, An YA, Field BC, Lee C, Matsuo EI, Mizerska M, Sanjana I, Fujiwara N, Kusminski CM, Gordillo R, Gautron L, Marciano DK, Hu MC, Burgess SC, Susztak K, Moe OW, Scherer PE. Onodera T, et al. Among authors: deja s. Nat Commun. 2023 Oct 17;14(1):6531. doi: 10.1038/s41467-023-42188-4. Nat Commun. 2023. PMID: 37848446 Free PMC article.
Effects of hepatic mitochondrial pyruvate carrier deficiency on de novo lipogenesis and glycerol-mediated gluconeogenesis in mice.
Yiew NKH, Deja S, Ferguson D, Cho K, Jarasvaraparn C, Jacome-Sosa M, Lutkewitte AJ, Mukherjee S, Fu X, Singer JM, Patti GJ, Burgess SC, Finck BN. Yiew NKH, et al. Among authors: deja s. bioRxiv [Preprint]. 2023 Aug 24:2023.02.17.528992. doi: 10.1101/2023.02.17.528992. bioRxiv. 2023. Update in: iScience. 2023 Oct 12;26(11):108196. doi: 10.1016/j.isci.2023.108196 PMID: 36824879 Free PMC article. Updated. Preprint.
Krebs takes a turn at cell differentiation.
Deja S, Crawford PA, Burgess SC. Deja S, et al. Cell Metab. 2022 May 3;34(5):658-660. doi: 10.1016/j.cmet.2022.04.005. Cell Metab. 2022. PMID: 35508108 Free article.
Gender-Specific Metabolomics Approach to Kidney Cancer.
Deja S, Litarski A, Mielko KA, Pudełko-Malik N, Wojtowicz W, Zabek A, Szydełko T, Młynarz P. Deja S, et al. Metabolites. 2021 Nov 10;11(11):767. doi: 10.3390/metabo11110767. Metabolites. 2021. PMID: 34822425 Free PMC article.
36 results