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Page 1
Induction of durable remission by dual immunotherapy in SHIV-infected ART-suppressed macaques.
Lim SY, Lee J, Osuna CE, Vikhe P, Schalk DR, Chen E, Fray E, Kumar M, Schultz-Darken N, Rakasz E, Capuano S, Ladd RA, Gil HM, Evans DT, Jeng EK, Seaman M, Martin M, Van Dorp C, Perelson AS, Wong HC, Siliciano JD, Siliciano R, Safrit JT, Nixon DF, Soon-Shiong P, Nussenzweig M, Whitney JB. Lim SY, et al. Among authors: safrit jt. Science. 2024 Mar 8;383(6687):1104-1111. doi: 10.1126/science.adf7966. Epub 2024 Feb 29. Science. 2024. PMID: 38422185 Free PMC article.
Biotech's role in advancing HIV vaccine development.
Tatoud R, Brander C, Hwang C, Kennelly J, Lu S, O'Neil K, Safrit JT, Benhayoun I, Firmat J, Barriere N. Tatoud R, et al. Among authors: safrit jt. Emerg Microbes Infect. 2024 Dec;13(1):2384460. doi: 10.1080/22221751.2024.2384460. Epub 2024 Aug 12. Emerg Microbes Infect. 2024. PMID: 39042015 Free PMC article. Review.
AZD5582 plus SIV-specific antibodies reduce lymph node viral reservoirs in antiretroviral therapy-suppressed macaques.
Dashti A, Sukkestad S, Horner AM, Neja M, Siddiqi Z, Waller C, Goldy J, Monroe D, Lin A, Schoof N, Singh V, Mavigner M, Lifson JD, Deleage C, Tuyishime M, Falcinelli SD, King HAD, Ke R, Mason RD, Archin NM, Dunham RM, Safrit JT, Jean S, Perelson AS, Margolis DM, Ferrari G, Roederer M, Silvestri G, Chahroudi A. Dashti A, et al. Among authors: safrit jt. Nat Med. 2023 Oct;29(10):2535-2546. doi: 10.1038/s41591-023-02570-7. Epub 2023 Oct 2. Nat Med. 2023. PMID: 37783968 Free PMC article.
Transient T Cell Expansion, Activation, and Proliferation in Therapeutically Vaccinated Simian Immunodeficiency Virus-Positive Macaques Treated with N-803.
Harwood OE, Balgeman AJ, Weaver AJ, Ellis-Connell AL, Weiler AM, Erickson KN, Matschke LM, Golfinos AE, Vezys V, Skinner PJ, Safrit JT, Edlefsen PT, Reynolds MR, Friedrich TC, O'Connor SL. Harwood OE, et al. Among authors: safrit jt. J Virol. 2022 Dec 14;96(23):e0142422. doi: 10.1128/jvi.01424-22. Epub 2022 Nov 15. J Virol. 2022. PMID: 36377872 Free PMC article.
Control of Simian Immunodeficiency Virus Infection in Prophylactically Vaccinated, Antiretroviral Treatment-Naive Macaques Is Required for the Most Efficacious CD8 T Cell Response during Treatment with the Interleukin-15 Superagonist N-803.
Ellis-Connell AL, Balgeman AJ, Harwood OE, Moriarty RV, Safrit JT, Weiler AM, Friedrich TC, O'Connor SL. Ellis-Connell AL, et al. Among authors: safrit jt. J Virol. 2022 Oct 26;96(20):e0118522. doi: 10.1128/jvi.01185-22. Epub 2022 Oct 3. J Virol. 2022. PMID: 36190241 Free PMC article.
Heterologous saRNA Prime, DNA Dual-Antigen Boost SARS-CoV-2 Vaccination Elicits Robust Cellular Immunogenicity and Cross-Variant Neutralizing Antibodies.
Rice A, Verma M, Voigt E, Battisti P, Beaver S, Reed S, Dinkins K, Mody S, Zakin L, Tanaka S, Morimoto B, Olson CA, Gabitzsch E, Safrit JT, Spilman P, Casper C, Soon-Shiong P. Rice A, et al. Among authors: safrit jt. Front Immunol. 2022 Jul 15;13:910136. doi: 10.3389/fimmu.2022.910136. eCollection 2022. Front Immunol. 2022. PMID: 35911728 Free PMC article.
Safety and virologic impact of the IL-15 superagonist N-803 in people living with HIV: a phase 1 trial.
Miller JS, Davis ZB, Helgeson E, Reilly C, Thorkelson A, Anderson J, Lima NS, Jorstad S, Hart GT, Lee JH, Safrit JT, Wong H, Cooley S, Gharu L, Chung H, Soon-Shiong P, Dobrowolski C, Fletcher CV, Karn J, Douek DC, Schacker TW. Miller JS, et al. Among authors: safrit jt. Nat Med. 2022 Feb;28(2):392-400. doi: 10.1038/s41591-021-01651-9. Epub 2022 Jan 31. Nat Med. 2022. PMID: 35102335 Clinical Trial.
Dual-Antigen COVID-19 Vaccine Subcutaneous Prime Delivery With Oral Boosts Protects NHP Against SARS-CoV-2 Challenge.
Gabitzsch E, Safrit JT, Verma M, Rice A, Sieling P, Zakin L, Shin A, Morimoto B, Adisetiyo H, Wong R, Bezawada A, Dinkins K, Balint J, Peykov V, Garban H, Liu P, Bacon A, Bone P, Drew J, Sanford DC, Spilman P, Sender L, Rabizadeh S, Niazi K, Soon-Shiong P. Gabitzsch E, et al. Among authors: safrit jt. Front Immunol. 2021 Sep 16;12:729837. doi: 10.3389/fimmu.2021.729837. eCollection 2021. Front Immunol. 2021. PMID: 34603305 Free PMC article.
61 results