Gershengorn MC - Search Results

1

An Orally Efficacious Thyrotropin Receptor Ligand Inhibits Growth and Metastatic Activity of Thyroid Cancers.

Sarkar R, Bolel P, Kapoor A, Eliseeva E, Dulcey AE, Templin JS, Wang AQ, Xu X, Southall N, Klubo-Gwiezdzinska J, Neumann S, Marugan JJ, Gershengorn MC. Sarkar R, et al. Among authors: gershengorn mc. J Clin Endocrinol Metab. 2024 Aug 13;109(9):2306-2316. doi: 10.1210/clinem/dgae114. J Clin Endocrinol Metab. 2024. PMID: 38421044 Free PMC article.

2

A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.

Neumann S, Huang W, Eliseeva E, Titus S, Thomas CJ, Gershengorn MC. Neumann S, et al. Among authors: gershengorn mc. Endocrinology. 2010 Jul;151(7):3454-9. doi: 10.1210/en.2010-0199. Epub 2010 Apr 28. Endocrinology. 2010. PMID: 20427476 Free PMC article.

3

A new small-molecule antagonist inhibits Graves' disease antibody activation of the TSH receptor.

Neumann S, Eliseeva E, McCoy JG, Napolitano G, Giuliani C, Monaco F, Huang W, Gershengorn MC. Neumann S, et al. Among authors: gershengorn mc. J Clin Endocrinol Metab. 2011 Feb;96(2):548-54. doi: 10.1210/jc.2010-1935. Epub 2010 Dec 1. J Clin Endocrinol Metab. 2011. PMID: 21123444 Free PMC article.

4

Update in TSH receptor agonists and antagonists.

Gershengorn MC, Neumann S. Gershengorn MC, et al. J Clin Endocrinol Metab. 2012 Dec;97(12):4287-92. doi: 10.1210/jc.2012-3080. Epub 2012 Sep 27. J Clin Endocrinol Metab. 2012. PMID: 23019348 Free PMC article. Review.

5

A selective TSH receptor antagonist inhibits stimulation of thyroid function in female mice.

Neumann S, Nir EA, Eliseeva E, Huang W, Marugan J, Xiao J, Dulcey AE, Gershengorn MC. Neumann S, et al. Among authors: gershengorn mc. Endocrinology. 2014 Jan;155(1):310-4. doi: 10.1210/en.2013-1835. Epub 2013 Dec 4. Endocrinology. 2014. PMID: 24169564 Free PMC article.

6

A low-molecular-weight antagonist for the human thyrotropin receptor with therapeutic potential for hyperthyroidism.

Neumann S, Kleinau G, Costanzi S, Moore S, Jiang JK, Raaka BM, Thomas CJ, Krause G, Gershengorn MC. Neumann S, et al. Among authors: gershengorn mc. Endocrinology. 2008 Dec;149(12):5945-50. doi: 10.1210/en.2008-0836. Epub 2008 Jul 31. Endocrinology. 2008. PMID: 18669595 Free PMC article.

7

β-Arrestin-1 mediates thyrotropin-enhanced osteoblast differentiation.

Boutin A, Eliseeva E, Gershengorn MC, Neumann S. Boutin A, et al. Among authors: gershengorn mc. FASEB J. 2014 Aug;28(8):3446-55. doi: 10.1096/fj.14-251124. Epub 2014 Apr 10. FASEB J. 2014. PMID: 24723693 Free PMC article.

8

Bidirectional TSH and IGF-1 receptor cross talk mediates stimulation of hyaluronan secretion by Graves' disease immunoglobins.

Krieger CC, Neumann S, Place RF, Marcus-Samuels B, Gershengorn MC. Krieger CC, et al. Among authors: gershengorn mc. J Clin Endocrinol Metab. 2015 Mar;100(3):1071-7. doi: 10.1210/jc.2014-3566. Epub 2014 Dec 8. J Clin Endocrinol Metab. 2015. PMID: 25485727 Free PMC article.

9

Multiple Transduction Pathways Mediate Thyrotropin Receptor Signaling in Preosteoblast-Like Cells.

Boutin A, Neumann S, Gershengorn MC. Boutin A, et al. Among authors: gershengorn mc. Endocrinology. 2016 May;157(5):2173-81. doi: 10.1210/en.2015-2040. Epub 2016 Mar 7. Endocrinology. 2016. PMID: 26950201 Free PMC article.

10

An Enantiomer of an Oral Small-Molecule TSH Receptor Agonist Exhibits Improved Pharmacologic Properties.

Neumann S, Padia U, Cullen MJ, Eliseeva E, Nir EA, Place RF, Morgan SJ, Gershengorn MC. Neumann S, et al. Among authors: gershengorn mc. Front Endocrinol (Lausanne). 2016 Jul 27;7:105. doi: 10.3389/fendo.2016.00105. eCollection 2016. Front Endocrinol (Lausanne). 2016. PMID: 27512388 Free PMC article.

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