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Decoding a cryptic mechanism of metronidazole resistance among globally disseminated fluoroquinolone-resistant Clostridioides difficile.
Olaitan AO, Dureja C, Youngblom MA, Topf MA, Shen WJ, Gonzales-Luna AJ, Deshpande A, Hevener KE, Freeman J, Wilcox MH, Palmer KL, Garey KW, Pepperell CS, Hurdle JG. Olaitan AO, et al. Among authors: dureja c. Nat Commun. 2023 Jul 12;14(1):4130. doi: 10.1038/s41467-023-39429-x. Nat Commun. 2023. PMID: 37438331 Free PMC article.
In vivo evaluation of Clostridioides difficile enoyl-ACP reductase II (FabK) Inhibition by phenylimidazole unveils a promising narrow-spectrum antimicrobial strategy.
Dureja C, Rutherford JT, Pavel FBA, Norseeda K, Prah I, Sun D, Hevener KE, Hurdle JG. Dureja C, et al. bioRxiv [Preprint]. 2023 Sep 22:2023.09.22.559005. doi: 10.1101/2023.09.22.559005. bioRxiv. 2023. Update in: Antimicrob Agents Chemother. 2024 Mar 6;68(3):e0122223. doi: 10.1128/aac.01222-23. PMID: 37790427 Free PMC article. Updated. Preprint.
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