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Whole genome-wide sequence analysis of long-lived families (Long-Life Family Study) identifies MTUS2 gene associated with late-onset Alzheimer's disease.
Xicota L, Cosentino S, Vardarajan B, Mayeux R, Perls TT, Andersen SL, Zmuda JM, Thyagarajan B, Yashin A, Wojczynski MK, Krinsky-McHale S, Handen BL, Christian BT, Head E, Mapstone ME, Schupf N, Lee JH, Barral S; Long‐Life Family Study (LLFS); Alzheimer's Disease Genetic Consortium (ADGC); Alzheimer's Biomarkers Consortium‐Down Syndrome (ABC‐DS). Xicota L, et al. Among authors: thyagarajan b. Alzheimers Dement. 2024 Apr;20(4):2670-2679. doi: 10.1002/alz.13718. Epub 2024 Feb 21. Alzheimers Dement. 2024. PMID: 38380866 Free PMC article.
Apolipoprotein E and familial longevity.
Schupf N, Barral S, Perls T, Newman A, Christensen K, Thyagarajan B, Province M, Rossi WK, Mayeux R. Schupf N, et al. Among authors: thyagarajan b. Neurobiol Aging. 2013 Apr;34(4):1287-91. doi: 10.1016/j.neurobiolaging.2012.08.019. Epub 2012 Oct 5. Neurobiol Aging. 2013. PMID: 23040522 Free PMC article.
Genome-wide association study identifies common loci influencing circulating glycated hemoglobin (HbA1c) levels in non-diabetic subjects: the Long Life Family Study (LLFS).
An P, Miljkovic I, Thyagarajan B, Kraja AT, Daw EW, Pankow JS, Selvin E, Kao WH, Maruthur NM, Nalls MA, Liu Y, Harris TB, Lee JH, Borecki IB, Christensen K, Eckfeldt JH, Mayeux R, Perls TT, Newman AB, Province MA. An P, et al. Among authors: thyagarajan b. Metabolism. 2014 Apr;63(4):461-8. doi: 10.1016/j.metabol.2013.11.018. Epub 2013 Dec 4. Metabolism. 2014. PMID: 24405752 Free PMC article.
Genetic variants associated with lung function: the long life family study.
Thyagarajan B, Wojczynski M, Minster RL, Sanders J, Barral S, Christiansen L, Barr RG, Newman A; CHARGE consortium, SpiroMeta consortium. Thyagarajan B, et al. Respir Res. 2014 Nov 1;15(1):134. doi: 10.1186/s12931-014-0134-x. Respir Res. 2014. PMID: 25409777 Free PMC article.
Heritability of telomere length in a study of long-lived families.
Honig LS, Kang MS, Cheng R, Eckfeldt JH, Thyagarajan B, Leiendecker-Foster C, Province MA, Sanders JL, Perls T, Christensen K, Lee JH, Mayeux R, Schupf N. Honig LS, et al. Among authors: thyagarajan b. Neurobiol Aging. 2015 Oct;36(10):2785-90. doi: 10.1016/j.neurobiolaging.2015.06.017. Epub 2015 Jun 18. Neurobiol Aging. 2015. PMID: 26239175 Free PMC article.
Candidate gene resequencing to identify rare, pedigree-specific variants influencing healthy aging phenotypes in the long life family study.
Druley TE, Wang L, Lin SJ, Lee JH, Zhang Q, Daw EW, Abel HJ, Chasnoff SE, Ramos EI, Levinson BT, Thyagarajan B, Newman AB, Christensen K, Mayeux R, Province MA. Druley TE, et al. Among authors: thyagarajan b. BMC Geriatr. 2016 Apr 9;16:80. doi: 10.1186/s12877-016-0253-y. BMC Geriatr. 2016. PMID: 27060904 Free PMC article.
Telomere length is longer in women with late maternal age.
Fagan E, Sun F, Bae H, Elo I, Andersen SL, Lee J, Christensen K, Thyagarajan B, Sebastiani P, Perls T, Honig LS, Schupf N; Long Life Family Study. Fagan E, et al. Among authors: thyagarajan b. Menopause. 2017 May;24(5):497-501. doi: 10.1097/GME.0000000000000795. Menopause. 2017. PMID: 27922939 Free PMC article.
Biomarker signatures of aging.
Sebastiani P, Thyagarajan B, Sun F, Schupf N, Newman AB, Montano M, Perls TT. Sebastiani P, et al. Among authors: thyagarajan b. Aging Cell. 2017 Apr;16(2):329-338. doi: 10.1111/acel.12557. Epub 2017 Jan 6. Aging Cell. 2017. PMID: 28058805 Free PMC article.
The APOE ε4 allele is associated with a reduction in FEV1/FVC in women: A cross-sectional analysis of the Long Life Family Study.
Kulminski AM, Barochia AV, Loika Y, Raghavachari N, Arbeev KG, Wojczynski MK, Thyagarajan B, Vardarajan BN, Christensen K, Yashin AI, Levine SJ. Kulminski AM, et al. Among authors: thyagarajan b. PLoS One. 2018 Nov 9;13(11):e0206873. doi: 10.1371/journal.pone.0206873. eCollection 2018. PLoS One. 2018. PMID: 30412599 Free PMC article.
360 results