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Regulatory T cells use heparanase to access IL-2 bound to extracellular matrix in inflamed tissue.
Martinez HA, Koliesnik I, Kaber G, Reid JK, Nagy N, Barlow G, Falk BA, Medina CO, Hargil A, Zihsler S, Vlodavsky I, Li JP, Pérez-Cruz M, Tang SW, Meyer EH, Wrenshall LE, Lord JD, Garcia KC, Palmer TD, Steinman L, Nepom GT, Wight TN, Bollyky PL, Kuipers HF. Martinez HA, et al. Among authors: koliesnik i. Nat Commun. 2024 Feb 20;15(1):1564. doi: 10.1038/s41467-024-45012-9. Nat Commun. 2024. PMID: 38378682 Free PMC article.
FOXP3+ regulatory T cells use heparanase to access IL-2 bound to ECM in inflamed tissues.
Martinez HA, Koliesnik I, Kaber G, Reid JK, Nagy N, Barlow G, Falk BA, Medina CO, Hargil A, Vlodavsky I, Li JP, Pérez-Cruz M, Tang SW, Meyer EH, Wrenshall LE, Lord JD, Garcia KC, Palmer TD, Steinman L, Nepom GT, Wight TN, Bollyky PL, Kuipers HF. Martinez HA, et al. Among authors: koliesnik i. bioRxiv [Preprint]. 2023 Feb 27:2023.02.26.529772. doi: 10.1101/2023.02.26.529772. bioRxiv. 2023. Update in: Nat Commun. 2024 Feb 20;15(1):1564. doi: 10.1038/s41467-024-45012-9. PMID: 36909599 Free PMC article. Updated. Preprint.
Calibration of cell-intrinsic interleukin-2 response thresholds guides design of a regulatory T cell biased agonist.
Glassman CR, Su L, Majri-Morrison SS, Winkelmann H, Mo F, Li P, Pérez-Cruz M, Ho PP, Koliesnik I, Nagy N, Hnizdilova T, Picton LK, Kovar M, Bollyky P, Steinman L, Meyer E, Piehler J, Leonard WJ, Garcia KC. Glassman CR, et al. Among authors: koliesnik i. Elife. 2021 May 18;10:e65777. doi: 10.7554/eLife.65777. Elife. 2021. PMID: 34003116 Free PMC article.
Correction: Dietary restriction improves repopulation but impairs lymphoid differentiation capacity of hematopoietic stem cells in early aging.
Tang D, Tao S, Chen Z, Koliesnik IO, Calmes PG, Hoerr V, Han B, Gebert N, Zörnig M, Löffler B, Morita Y, Rudolph KL. Tang D, et al. Among authors: koliesnik io. J Exp Med. 2021 Jan 4;218(1):jem.2015110012042020C. doi: 10.1084/jem.2015110012042020C. J Exp Med. 2021. PMID: 33331868 Free PMC article. No abstract available.
Quantitative assessment of bacterial growth phase utilizing flow cytometry.
Khomtchouk KM, Weglarz M, Bekale LA, Koliesnik I, Bollyky PL, Santa Maria PL. Khomtchouk KM, et al. Among authors: koliesnik i. J Microbiol Methods. 2019 Dec;167:105760. doi: 10.1016/j.mimet.2019.105760. Epub 2019 Oct 31. J Microbiol Methods. 2019. PMID: 31678132 Free PMC article.
Natural Tr1-like cells do not confer long-term tolerogenic memory.
Yadava K, Medina CO, Ishak H, Gurevich I, Kuipers H, Shamskhou EA, Koliesnik IO, Moon JJ, Weaver C, Nadeau KC, Bollyky PL. Yadava K, et al. Among authors: koliesnik io. Elife. 2019 Oct 11;8:e44821. doi: 10.7554/eLife.44821. Elife. 2019. PMID: 31603425 Free PMC article.
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