Zhang Q - Search Results

1

Potentiating the radiation-induced type I interferon antitumoral immune response by ATM inhibition in pancreatic cancer.

Zhang Q, Jiang L, Wang W, Huber AK, Valvo VM, Jungles KM, Holcomb EA, Pearson AN, The S, Wang Z, Parsels LA, Parsels JD, Wahl DR, Rao A, Sahai V, Lawrence TS, Green MD, Morgan MA. Zhang Q, et al. JCI Insight. 2024 Feb 20;9(6):e168824. doi: 10.1172/jci.insight.168824. JCI Insight. 2024. PMID: 38376927 Free PMC article.

2

Inhibition of ATM Increases Interferon Signaling and Sensitizes Pancreatic Cancer to Immune Checkpoint Blockade Therapy.

Zhang Q, Green MD, Lang X, Lazarus J, Parsels JD, Wei S, Parsels LA, Shi J, Ramnath N, Wahl DR, Pasca di Magliano M, Frankel TL, Kryczek I, Lei YL, Lawrence TS, Zou W, Morgan MA. Zhang Q, et al. Cancer Res. 2019 Aug 1;79(15):3940-3951. doi: 10.1158/0008-5472.CAN-19-0761. Epub 2019 May 17. Cancer Res. 2019. PMID: 31101760 Free PMC article.

3

Sensitization of pancreatic cancer to chemoradiation by the Chk1 inhibitor MK8776.

Engelke CG, Parsels LA, Qian Y, Zhang Q, Karnak D, Robertson JR, Tanska DM, Wei D, Davis MA, Parsels JD, Zhao L, Greenson JK, Lawrence TS, Maybaum J, Morgan MA. Engelke CG, et al. Among authors: zhang q. Clin Cancer Res. 2013 Aug 15;19(16):4412-21. doi: 10.1158/1078-0432.CCR-12-3748. Epub 2013 Jun 26. Clin Cancer Res. 2013. PMID: 23804422 Free PMC article.

4

PARP1 Trapping and DNA Replication Stress Enhance Radiosensitization with Combined WEE1 and PARP Inhibitors.

Parsels LA, Karnak D, Parsels JD, Zhang Q, Vélez-Padilla J, Reichert ZR, Wahl DR, Maybaum J, O'Connor MJ, Lawrence TS, Morgan MA. Parsels LA, et al. Among authors: zhang q. Mol Cancer Res. 2018 Feb;16(2):222-232. doi: 10.1158/1541-7786.MCR-17-0455. Epub 2017 Nov 13. Mol Cancer Res. 2018. PMID: 29133592 Free PMC article.

5

Combinatorial Efficacy of Olaparib with Radiation and ATR Inhibitor Requires PARP1 Protein in Homologous Recombination-Proficient Pancreatic Cancer.

Parsels LA, Engelke CG, Parsels J, Flanagan SA, Zhang Q, Tanska D, Wahl DR, Canman CE, Lawrence TS, Morgan MA. Parsels LA, et al. Among authors: zhang q. Mol Cancer Ther. 2021 Feb;20(2):263-273. doi: 10.1158/1535-7163.MCT-20-0365. Epub 2020 Dec 2. Mol Cancer Ther. 2021. PMID: 33268569 Free PMC article.

6

Cytidine Deaminase APOBEC3A Regulates PD-L1 Expression in Cancer Cells in a JNK/c-JUN-Dependent Manner.

Zhao K, Zhang Q, Flanagan SA, Lang X, Jiang L, Parsels LA, Parsels JD, Zou W, Lawrence TS, Buisson R, Green MD, Morgan MA. Zhao K, et al. Among authors: zhang q. Mol Cancer Res. 2021 Sep;19(9):1571-1582. doi: 10.1158/1541-7786.MCR-21-0219. Epub 2021 May 27. Mol Cancer Res. 2021. PMID: 34045311 Free PMC article.

7

Translation of DNA Damage Response Inhibitors as Chemoradiation Sensitizers From the Laboratory to the Clinic.

Parsels LA, Zhang Q, Karnak D, Parsels JD, Lam K, Willers H, Green MD, Rehemtulla A, Lawrence TS, Morgan MA. Parsels LA, et al. Among authors: zhang q. Int J Radiat Oncol Biol Phys. 2021 Dec 1;111(5):e38-e53. doi: 10.1016/j.ijrobp.2021.07.1708. Epub 2021 Aug 1. Int J Radiat Oncol Biol Phys. 2021. PMID: 34348175 Free PMC article.

8

DNA-PK Inhibition and Radiation Promote Antitumoral Immunity through RNA Polymerase III in Pancreatic Cancer.

Wang W, McMillan MT, Zhao X, Wang Z, Jiang L, Karnak D, Lima F, Parsels JD, Parsels LA, Lawrence TS, Frankel TL, Morgan MA, Green MD, Zhang Q. Wang W, et al. Among authors: zhang q. Mol Cancer Res. 2022 Jul 6;20(7):1137-1150. doi: 10.1158/1541-7786.MCR-21-0725. Mol Cancer Res. 2022. PMID: 35348737 Free PMC article.

9

Targeting mcl-1 for radiosensitization of pancreatic cancers.

Wei D, Zhang Q, Schreiber JS, Parsels LA, Abulwerdi FA, Kausar T, Lawrence TS, Sun Y, Nikolovska-Coleska Z, Morgan MA. Wei D, et al. Among authors: zhang q. Transl Oncol. 2015 Feb;8(1):47-54. doi: 10.1016/j.tranon.2014.12.004. Transl Oncol. 2015. PMID: 25749177 Free PMC article.

10

FBXW7 Facilitates Nonhomologous End-Joining via K63-Linked Polyubiquitylation of XRCC4.

Zhang Q, Karnak D, Tan M, Lawrence TS, Morgan MA, Sun Y. Zhang Q, et al. Mol Cell. 2016 Feb 4;61(3):419-433. doi: 10.1016/j.molcel.2015.12.010. Epub 2016 Jan 7. Mol Cell. 2016. PMID: 26774286 Free PMC article.

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