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P7C3-A20 alleviates fatty liver by shaping gut microbiota and inducing FGF21/FGF1, via the AMP-activated protein kinase/CREB regulated transcription coactivator 2 pathway.
Hua X, Sun DY, Zhang WJ, Fu JT, Tong J, Sun SJ, Zeng FY, Ouyang SX, Zhang GY, Wang SN, Li DJ, Miao CY, Wang P. Hua X, et al. Among authors: ouyang sx. Br J Pharmacol. 2021 May;178(10):2111-2130. doi: 10.1111/bph.15008. Epub 2020 Mar 24. Br J Pharmacol. 2021. PMID: 32037512 Free article.
Targeting a novel inducible GPX4 alternative isoform to alleviate ferroptosis and treat metabolic-associated fatty liver disease.
Tong J, Li D, Meng H, Sun D, Lan X, Ni M, Ma J, Zeng F, Sun S, Fu J, Li G, Ji Q, Zhang G, Shen Q, Wang Y, Zhu J, Zhao Y, Wang X, Liu Y, Ouyang S, Sheng C, Shen F, Wang P. Tong J, et al. Acta Pharm Sin B. 2022 Sep;12(9):3650-3666. doi: 10.1016/j.apsb.2022.02.003. Epub 2022 Feb 12. Acta Pharm Sin B. 2022. PMID: 36176906 Free PMC article.
GSDME promotes MASLD by regulating pyroptosis, Drp1 citrullination-dependent mitochondrial dynamic, and energy balance in intestine and liver.
Zhu JH, Ouyang SX, Zhang GY, Cao Q, Xin R, Yin H, Wu JW, Zhang Y, Zhang Z, Liu Y, Fu JT, Chen YT, Tong J, Zhang JB, Liu J, Shen FM, Li DJ, Wang P. Zhu JH, et al. Among authors: ouyang sx. Cell Death Differ. 2024 Nov;31(11):1467-1486. doi: 10.1038/s41418-024-01343-0. Epub 2024 Jul 16. Cell Death Differ. 2024. PMID: 39009654
20 results