Kirschner D - Search Results

1

Forum on immune digital twins: a meeting report.

Laubenbacher R, Adler F, An G, Castiglione F, Eubank S, Fonseca LL, Glazier J, Helikar T, Jett-Tilton M, Kirschner D, Macklin P, Mehrad B, Moore B, Pasour V, Shmulevich I, Smith A, Voigt I, Yankeelov TE, Ziemssen T. Laubenbacher R, et al. Among authors: kirschner d. NPJ Syst Biol Appl. 2024 Feb 16;10(1):19. doi: 10.1038/s41540-024-00345-5. NPJ Syst Biol Appl. 2024. PMID: 38365857 Free PMC article. Review.

2

Toward mechanistic medical digital twins: some use cases in immunology.

Laubenbacher R, Adler F, An G, Castiglione F, Eubank S, Fonseca LL, Glazier J, Helikar T, Jett-Tilton M, Kirschner D, Macklin P, Mehrad B, Moore B, Pasour V, Shmulevich I, Smith A, Voigt I, Yankeelov TE, Ziemssen T. Laubenbacher R, et al. Among authors: kirschner d. Front Digit Health. 2024 Mar 7;6:1349595. doi: 10.3389/fdgth.2024.1349595. eCollection 2024. Front Digit Health. 2024. PMID: 38515550 Free PMC article. Review.

3

A multifaceted approach to modeling the immune response in tuberculosis.

Marino S, Linderman JJ, Kirschner DE. Marino S, et al. Wiley Interdiscip Rev Syst Biol Med. 2011 Jul-Aug;3(4):479-89. doi: 10.1002/wsbm.131. Epub 2010 Dec 31. Wiley Interdiscip Rev Syst Biol Med. 2011. PMID: 21197656 Free PMC article. Review.

4

A framework for multi-scale intervention modeling: virtual cohorts, virtual clinical trials, and model-to-model comparisons.

Michael CT, Almohri SA, Linderman JJ, Kirschner DE. Michael CT, et al. Front Syst Biol. 2023;3:1283341. doi: 10.3389/fsysb.2023.1283341. Epub 2024 Jan 21. Front Syst Biol. 2023. PMID: 39310676 Free PMC article.

5

Modeling immunotherapy of the tumor-immune interaction.

Kirschner D, Panetta JC. Kirschner D, et al. J Math Biol. 1998 Sep;37(3):235-52. doi: 10.1007/s002850050127. J Math Biol. 1998. PMID: 9785481 Free article.

6

Tuneable resolution as a systems biology approach for multi-scale, multi-compartment computational models.

Kirschner DE, Hunt CA, Marino S, Fallahi-Sichani M, Linderman JJ. Kirschner DE, et al. Wiley Interdiscip Rev Syst Biol Med. 2014 Jul-Aug;6(4):289-309. doi: 10.1002/wsbm.1270. Epub 2014 May 9. Wiley Interdiscip Rev Syst Biol Med. 2014. PMID: 24810243 Free PMC article. Review.

7

A review of computational and mathematical modeling contributions to our understanding of Mycobacterium tuberculosis within-host infection and treatment.

Kirschner D, Pienaar E, Marino S, Linderman JJ. Kirschner D, et al. Curr Opin Syst Biol. 2017 Jun;3:170-185. doi: 10.1016/j.coisb.2017.05.014. Epub 2017 May 22. Curr Opin Syst Biol. 2017. PMID: 30714019 Free PMC article.

8

Identifying DNA splice sites using hypernetworks with artificial molecular evolution.

Segovia-Juarez JL, Colombano S, Kirschner D. Segovia-Juarez JL, et al. Among authors: kirschner d. Biosystems. 2007 Feb;87(2-3):117-24. doi: 10.1016/j.biosystems.2006.09.004. Epub 2006 Sep 7. Biosystems. 2007. PMID: 17116361

9

In silico models of M. tuberculosis infection provide a route to new therapies.

Linderman JJ, Kirschner DE. Linderman JJ, et al. Drug Discov Today Dis Models. 2015 Spring;15:37-41. doi: 10.1016/j.ddmod.2014.02.006. Epub 2014 May 9. Drug Discov Today Dis Models. 2015. PMID: 26904139 Free PMC article.

10

Data-Driven Model Validation Across Dimensions.

Renardy M, Wessler T, Blemker S, Linderman J, Peirce S, Kirschner D. Renardy M, et al. Among authors: kirschner d. Bull Math Biol. 2019 Jun;81(6):1853-1866. doi: 10.1007/s11538-019-00590-4. Epub 2019 Mar 4. Bull Math Biol. 2019. PMID: 30830675 Free PMC article.

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