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Page 1
Drp1 splice variants regulate ovarian cancer mitochondrial dynamics and tumor progression.
Javed Z, Shin DH, Pan W, White SR, Elhaw AT, Kim YS, Kamlapurkar S, Cheng YY, Benson JC, Abdelnaby AE, Phaëton R, Wang HG, Yang S, Sullivan MLG, St Croix CM, Watkins SC, Mullett SJ, Gelhaus SL, Lee N, Coffman LG, Aird KM, Trebak M, Mythreye K, Walter V, Hempel N. Javed Z, et al. Among authors: phaeton r. EMBO Rep. 2024 Oct;25(10):4281-4310. doi: 10.1038/s44319-024-00232-4. Epub 2024 Aug 27. EMBO Rep. 2024. PMID: 39191946 Free PMC article.
Glycosaminoglycan modifications of betaglycan regulate ectodomain shedding to fine-tune TGF-β signaling responses in ovarian cancer.
Choi AS, Jenkins-Lane LM, Barton W, Kumari A, Lancaster C, Raulerson C, Ji H, Altomare D, Starr MD, Whitaker R, Phaeton R, Arend R, Shtutman M, Nixon AB, Hempel N, Lee NY, Mythreye K. Choi AS, et al. Among authors: phaeton r. Cell Commun Signal. 2024 Feb 15;22(1):128. doi: 10.1186/s12964-024-01496-y. Cell Commun Signal. 2024. PMID: 38360757 Free PMC article.
GPX3 supports ovarian cancer tumor progression in vivo and promotes expression of GDF15.
Chang C, Cheng YY, Kamlapurkar S, White SR, Tang PW, Elhaw AT, Javed Z, Aird KM, Mythreye K, Phaëton R, Hempel N. Chang C, et al. Among authors: phaeton r. bioRxiv [Preprint]. 2024 Jan 29:2024.01.24.577037. doi: 10.1101/2024.01.24.577037. bioRxiv. 2024. Update in: Gynecol Oncol. 2024 Jun;185:8-16. doi: 10.1016/j.ygyno.2024.02.004 PMID: 38352432 Free PMC article. Updated. Preprint.
Alternative splice variants of the mitochondrial fission protein DNM1L/Drp1 regulate mitochondrial dynamics and tumor progression in ovarian cancer.
Javed Z, Shin DH, Pan W, White SR, Kim YS, Elhaw AT, Kamlapurkar S, Cheng YY, Benson JC, Abdelnaby AE, Phaëton R, Wang HG, Yang S, Sullivan MLG, St Croix CM, Watkins SC, Mullett SJ, Gelhaus SL, Lee N, Coffman LG, Aird KM, Trebak M, Mythreye K, Walter V, Hempel N. Javed Z, et al. Among authors: phaeton r. bioRxiv [Preprint]. 2024 Jan 24:2023.09.20.558501. doi: 10.1101/2023.09.20.558501. bioRxiv. 2024. Update in: EMBO Rep. 2024 Oct;25(10):4281-4310. doi: 10.1038/s44319-024-00232-4 PMID: 37790404 Free PMC article. Updated. Preprint.
Heparan sulfate modifications of betaglycan promote TIMP3-dependent ectodomain shedding to fine-tune TGF-β signaling.
Choi AS, Jenkins-Lane LM, Barton W, Kumari A, Lancaster C, Raulerson C, Ji H, Altomare D, Starr MD, Whitaker R, Phaeton R, Arend R, Shtutman M, Nixon AB, Hempel N, Lee NY, Mythreye K. Choi AS, et al. Among authors: phaeton r. bioRxiv [Preprint]. 2023 Aug 29:2023.08.29.555364. doi: 10.1101/2023.08.29.555364. bioRxiv. 2023. Update in: Cell Commun Signal. 2024 Feb 15;22(1):128. doi: 10.1186/s12964-024-01496-y PMID: 37693479 Free PMC article. Updated. Preprint.
Reciprocal SOX2 regulation by SMAD1-SMAD3 is critical for anoikis resistance and metastasis in cancer.
Shonibare Z, Monavarian M, O'Connell K, Altomare D, Shelton A, Mehta S, Jaskula-Sztul R, Phaeton R, Starr MD, Whitaker R, Berchuck A, Nixon AB, Arend RC, Lee NY, Miller CR, Hempel N, Mythreye K. Shonibare Z, et al. Among authors: phaeton r. Cell Rep. 2022 Jul 26;40(4):111066. doi: 10.1016/j.celrep.2022.111066. Cell Rep. 2022. PMID: 35905726 Free PMC article.
Context-dependent activation of SIRT3 is necessary for anchorage-independent survival and metastasis of ovarian cancer cells.
Kim YS, Gupta Vallur P, Jones VM, Worley BL, Shimko S, Shin DH, Crawford LC, Chen CW, Aird KM, Abraham T, Shepherd TG, Warrick JI, Lee NY, Phaeton R, Mythreye K, Hempel N. Kim YS, et al. Among authors: phaeton r. Oncogene. 2020 Feb;39(8):1619-1633. doi: 10.1038/s41388-019-1097-7. Epub 2019 Nov 13. Oncogene. 2020. PMID: 31723239 Free PMC article.
24 results