Longhurst HJ - Search Results

1

The autoimmune rheumatological presentation of Common Variable Immunodeficiency Disorders with an overview of genetic testing.

Ameratunga R, Woon ST, Leung E, Lea E, Chan L, Mehrtens J, Longhurst HJ, Steele R, Lehnert K, Lindsay K. Ameratunga R, et al. Among authors: longhurst hj. Semin Arthritis Rheum. 2024 Apr;65:152387. doi: 10.1016/j.semarthrit.2024.152387. Epub 2024 Jan 17. Semin Arthritis Rheum. 2024. PMID: 38330740 Review.

2

The Rapidly Expanding Genetic Spectrum of Common Variable Immunodeficiency-Like Disorders.

Ameratunga R, Edwards ESJ, Lehnert K, Leung E, Woon ST, Lea E, Allan C, Chan L, Steele R, Longhurst H, Bryant VL. Ameratunga R, et al. J Allergy Clin Immunol Pract. 2023 Jun;11(6):1646-1664. doi: 10.1016/j.jaip.2023.01.048. Epub 2023 Feb 14. J Allergy Clin Immunol Pract. 2023. PMID: 36796510 Review.

3

Soluble wild-type ACE2 molecules inhibit newer SARS-CoV-2 variants and are a potential antiviral strategy to mitigate disease severity in COVID-19.

Ameratunga R, Mears E, Leung E, Snell R, Woon ST, Kelton W, Medlicott N, Jordan A, Abbott W, Steele R, Rolleston W, Longhurst H, Lehnert K. Ameratunga R, et al. Clin Exp Immunol. 2023 Dec 13;214(3):289-295. doi: 10.1093/cei/uxad096. Clin Exp Immunol. 2023. PMID: 37565297 Free PMC article.

4

Challenges for gene editing in common variable immunodeficiency disorders: Current and future prospects.

Ameratunga R, Leung E, Woon ST, Lea E, Allan C, Chan L, Longhurst H, Steele R, Snell R, Lehnert K. Ameratunga R, et al. Clin Immunol. 2024 Jan;258:109854. doi: 10.1016/j.clim.2023.109854. Epub 2023 Nov 25. Clin Immunol. 2024. PMID: 38013164 Review.

5

Limitations in the clinical utility of vaccine challenge responses in the evaluation of primary antibody deficiency including Common Variable Immunodeficiency Disorders.

Ameratunga R, Longhurst H, Leung E, Steele R, Lehnert K, Woon ST. Ameratunga R, et al. Clin Immunol. 2024 Sep;266:110320. doi: 10.1016/j.clim.2024.110320. Epub 2024 Jul 25. Clin Immunol. 2024. PMID: 39025346

6

Loss-of-function nuclear factor κB subunit 1 (NFKB1) variants are the most common monogenic cause of common variable immunodeficiency in Europeans.

Tuijnenburg P, Lango Allen H, Burns SO, Greene D, Jansen MH, Staples E, Stephens J, Carss KJ, Biasci D, Baxendale H, Thomas M, Chandra A, Kiani-Alikhan S, Longhurst HJ, Seneviratne SL, Oksenhendler E, Simeoni I, de Bree GJ, Tool ATJ, van Leeuwen EMM, Ebberink EHTM, Meijer AB, Tuna S, Whitehorn D, Brown M, Turro E, Thrasher AJ, Smith KGC, Thaventhiran JE, Kuijpers TW; NIHR BioResource–Rare Diseases Consortium. Tuijnenburg P, et al. Among authors: longhurst hj. J Allergy Clin Immunol. 2018 Oct;142(4):1285-1296. doi: 10.1016/j.jaci.2018.01.039. Epub 2018 Mar 2. J Allergy Clin Immunol. 2018. PMID: 29477724 Free PMC article.

7

A Review of Randomized Controlled Trials of Hereditary Angioedema Long-Term Prophylaxis with C1 Inhibitor Replacement Therapy: Alleviation of Disease Symptoms Is Achievable.

Longhurst HJ, Valerieva A. Longhurst HJ, et al. J Asthma Allergy. 2023 Mar 9;16:269-277. doi: 10.2147/JAA.S396338. eCollection 2023. J Asthma Allergy. 2023. PMID: 36922963 Free PMC article. Review.

8

Different phenotypes with different endings-Telomere biology disorders and cancer predisposition with long telomeres.

Savage SA, Bertuch AA; Team Telomere and the Clinical Care Consortium for Telomere‐Associated Ailments (CCCTAA). Savage SA, et al. Br J Haematol. 2024 Oct 27. doi: 10.1111/bjh.19851. Online ahead of print. Br J Haematol. 2024. PMID: 39462986 Review.

9

CRISPR-Based Therapy for Hereditary Angioedema.

Cohn DM, Gurugama P, Magerl M, Katelaris CH, Launay D, Bouillet L, Petersen RS, Lindsay K, Aygören-Pürsün E, Maag D, Butler JS, Shah MY, Golden A, Xu Y, Abdelhady AM, Lebwohl D, Longhurst HJ. Cohn DM, et al. Among authors: longhurst hj. N Engl J Med. 2024 Oct 24. doi: 10.1056/NEJMoa2405734. Online ahead of print. N Engl J Med. 2024. PMID: 39445704

10

The complexities of decision-making associated with on-demand treatment of hereditary angioedema (HAE) attacks.

Betschel SD, Caballero T, Jones DH, Longhurst HJ, Manning M, van Kooten S, Heckmann M, Danese S, Goga L, Burnette AF. Betschel SD, et al. Among authors: longhurst hj. Allergy Asthma Clin Immunol. 2024 Jul 25;20(1):43. doi: 10.1186/s13223-024-00903-w. Allergy Asthma Clin Immunol. 2024. PMID: 39049074 Free PMC article.

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