Kuwahara Y - Search Results

1

Overcoming Clinical Resistance to EZH2 Inhibition Using Rational Epigenetic Combination Therapy.

Kazansky Y, Cameron D, Mueller HS, Demarest P, Zaffaroni N, Arrighetti N, Zuco V, Kuwahara Y, Somwar R, Ladanyi M, Qu R, de Stanchina E, Dela Cruz FS, Kung AL, Gounder MM, Kentsis A. Kazansky Y, et al. Among authors: kuwahara y. Cancer Discov. 2024 Jun 3;14(6):965-981. doi: 10.1158/2159-8290.CD-23-0110. Cancer Discov. 2024. PMID: 38315003

2

Therapeutic targeting of PGBD5-induced DNA repair dependency in pediatric solid tumors.

Henssen AG, Reed C, Jiang E, Garcia HD, von Stebut J, MacArthur IC, Hundsdoerfer P, Kim JH, de Stanchina E, Kuwahara Y, Hosoi H, Ganem NJ, Dela Cruz F, Kung AL, Schulte JH, Petrini JH, Kentsis A. Henssen AG, et al. Among authors: kuwahara y. Sci Transl Med. 2017 Nov 1;9(414):eaam9078. doi: 10.1126/scitranslmed.aam9078. Sci Transl Med. 2017. PMID: 29093183 Free PMC article.

3

Recent insights into the SWI/SNF complex and the molecular mechanism of hSNF5 deficiency in rhabdoid tumors.

Kuwahara Y, Iehara T, Matsumoto A, Okuda T. Kuwahara Y, et al. Cancer Med. 2023 Aug;12(15):16323-16336. doi: 10.1002/cam4.6255. Epub 2023 Jun 14. Cancer Med. 2023. PMID: 37317642 Free PMC article. Review.

4

The Novel Histone Deacetylase Inhibitor, OBP-801, Induces Apoptosis in Rhabdoid Tumors by Releasing the Silencing of NOXA.

Sugimoto Y, Katsumi Y, Iehara T, Kaneda D, Tomoyasu C, Ouchi K, Yoshida H, Miyachi M, Yagyu S, Kikuchi K, Tsuchiya K, Kuwahara Y, Sakai T, Hosoi H. Sugimoto Y, et al. Among authors: kuwahara y. Mol Cancer Ther. 2020 Oct;19(10):1992-2000. doi: 10.1158/1535-7163.MCT-20-0243. Epub 2020 Aug 26. Mol Cancer Ther. 2020. PMID: 32847975

5

A NOXA/MCL-1 Imbalance Underlies Chemoresistance of Malignant Rhabdoid Tumor Cells.

Ouchi K, Kuwahara Y, Iehara T, Miyachi M, Katsumi Y, Tsuchiya K, Konishi E, Yanagisawa A, Hosoi H. Ouchi K, et al. Among authors: kuwahara y. J Cell Physiol. 2016 Sep;231(9):1932-40. doi: 10.1002/jcp.25293. Epub 2016 Jan 14. J Cell Physiol. 2016. PMID: 26680268

6

Dual targeting of EZH1 and EZH2 for the treatment of malignant rhabdoid tumors.

Shinohara H, Sawado R, Nakagawa M, Hattori A, Yamagata K, Tauchi K, Ito J, Kuwahara Y, Okuda T, Ogawa C, Kitabayashi I. Shinohara H, et al. Among authors: kuwahara y. Mol Ther Oncolytics. 2022 Sep 19;27:14-25. doi: 10.1016/j.omto.2022.09.006. eCollection 2022 Dec 15. Mol Ther Oncolytics. 2022. PMID: 36212776 Free PMC article.

7

Oncogenic role of HMGA2 in fusion-negative rhabdomyosarcoma cells.

Ouchi K, Miyachi M, Yagyu S, Kikuchi K, Kuwahara Y, Tsuchiya K, Iehara T, Hosoi H. Ouchi K, et al. Among authors: kuwahara y. Cancer Cell Int. 2020 May 24;20:192. doi: 10.1186/s12935-020-01282-z. eCollection 2020. Cancer Cell Int. 2020. PMID: 32489328 Free PMC article.

8

Reexpression of hSNF5 in malignant rhabdoid tumor cell lines causes cell cycle arrest through a p21(CIP1/WAF1)-dependent mechanism.

Kuwahara Y, Charboneau A, Knudsen ES, Weissman BE. Kuwahara Y, et al. Cancer Res. 2010 Mar 1;70(5):1854-65. doi: 10.1158/0008-5472.CAN-09-1922. Epub 2010 Feb 23. Cancer Res. 2010. PMID: 20179200 Free PMC article.

9

Identification of COL3A1 and RAB2A as novel translocation partner genes of PLAG1 in lipoblastoma.

Yoshida H, Miyachi M, Ouchi K, Kuwahara Y, Tsuchiya K, Iehara T, Konishi E, Yanagisawa A, Hosoi H. Yoshida H, et al. Among authors: kuwahara y. Genes Chromosomes Cancer. 2014 Jul;53(7):606-11. doi: 10.1002/gcc.22170. Epub 2014 Apr 4. Genes Chromosomes Cancer. 2014. PMID: 24700772

10

Establishment and characterization of MRT cell lines from genetically engineered mouse models and the influence of genetic background on their development.

Kuwahara Y, Mora-Blanco EL, Banine F, Rogers AB, Fletcher C, Sherman LS, Roberts CW, Weissman BE. Kuwahara Y, et al. Int J Cancer. 2013 Jun 15;132(12):2767-77. doi: 10.1002/ijc.27976. Epub 2012 Dec 27. Int J Cancer. 2013. PMID: 23197309 Free PMC article.

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