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Behavioral, metabolic, and lipidomic characterization of the 5xFADxTg30 mouse model of Alzheimer's disease.
Marshall JPS, Huynh K, Lancaster GI, Ng J, Collins JM, Pernes G, Liang A, Featherby T, Mellet NA, Drew BG, Calkin AC, King AE, Meikle PJ, Febbraio MA, Adlard PA, Henstridge DC. Marshall JPS, et al. Among authors: febbraio ma. iScience. 2024 Jan 4;27(2):108800. doi: 10.1016/j.isci.2024.108800. eCollection 2024 Feb 16. iScience. 2024. PMID: 38292430 Free PMC article.
Class IIa HDACs inhibit cell death pathways and protect muscle integrity in response to lipotoxicity.
Martin SD, Connor T, Sanigorski A, McEwen KA, Henstridge DC, Nijagal B, De Souza D, Tull DL, Meikle PJ, Kowalski GM, Bruce CR, Gregorevic P, Febbraio MA, Collier FM, Walder KR, McGee SL. Martin SD, et al. Among authors: febbraio ma. Cell Death Dis. 2023 Dec 1;14(12):787. doi: 10.1038/s41419-023-06319-5. Cell Death Dis. 2023. PMID: 38040704 Free PMC article.
ACAD10 is not required for metformin's metabolic actions or for maintenance of whole-body metabolism in C57BL/6J mice.
Yew MJ, Heywood SE, Ng J, West OM, Pal M, Kueh A, Lancaster GI, Myers S, Yang C, Liu Y, Reibe S, Mellett NA, Meikle PJ, Febbraio MA, Greening DW, Drew BG, Henstridge DC. Yew MJ, et al. Among authors: febbraio ma. Diabetes Obes Metab. 2024 May;26(5):1731-1745. doi: 10.1111/dom.15484. Epub 2024 Feb 13. Diabetes Obes Metab. 2024. PMID: 38351663
CaMKK2 as an emerging treatment target for bipolar disorder.
Kaiser J, Nay K, Horne CR, McAloon LM, Fuller OK, Muller AG, Whyte DG, Means AR, Walder K, Berk M, Hannan AJ, Murphy JM, Febbraio MA, Gundlach AL, Scott JW. Kaiser J, et al. Among authors: febbraio ma. Mol Psychiatry. 2023 Nov;28(11):4500-4511. doi: 10.1038/s41380-023-02260-3. Epub 2023 Sep 20. Mol Psychiatry. 2023. PMID: 37730845 Free PMC article. Review.
CaMKK2: bridging the gap between Ca2+ signaling and energy-sensing.
McAloon LM, Muller AG, Nay K, Lu EL, Smeuninx B, Means AR, Febbraio MA, Scott JW. McAloon LM, et al. Among authors: febbraio ma. Essays Biochem. 2024 Sep 13:EBC20240011. doi: 10.1042/EBC20240011. Online ahead of print. Essays Biochem. 2024. PMID: 39268917
Embracing cancer complexity: Hallmarks of systemic disease.
Swanton C, Bernard E, Abbosh C, André F, Auwerx J, Balmain A, Bar-Sagi D, Bernards R, Bullman S, DeGregori J, Elliott C, Erez A, Evan G, Febbraio MA, Hidalgo A, Jamal-Hanjani M, Joyce JA, Kaiser M, Lamia K, Locasale JW, Loi S, Malanchi I, Merad M, Musgrave K, Patel KJ, Quezada S, Wargo JA, Weeraratna A, White E, Winkler F, Wood JN, Vousden KH, Hanahan D. Swanton C, et al. Among authors: febbraio ma. Cell. 2024 Mar 28;187(7):1589-1616. doi: 10.1016/j.cell.2024.02.009. Cell. 2024. PMID: 38552609 Review.
Therapeutic blockade of ER stress and inflammation prevents NASH and progression to HCC.
Boslem E, Reibe S, Carlessi R, Smeuninx B, Tegegne S, Egan CL, McLennan E, Terry LV, Nobis M, Mu A, Nowell C, Horadagoda N, Henstridge DC, Mellett NA, Timpson P, Jones M, Denisenko E, Forrest ARR, Tirnitz-Parker JEE, Meikle PJ, Rose-John S, Karin M, Febbraio MA. Boslem E, et al. Among authors: febbraio ma. Sci Adv. 2023 Sep 15;9(37):eadh0831. doi: 10.1126/sciadv.adh0831. Epub 2023 Sep 13. Sci Adv. 2023. PMID: 37703359 Free PMC article.
280 results